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P22506 (BGL1_SACFI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase 1

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene names
Name:BGL1
OrganismSaccharomycopsis fibuligera (Yeast)
Taxonomic identifier4944 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycopsidaceaeSaccharomycopsis

Protein attributes

Sequence length876 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717
Chain18 – 876859Beta-glucosidase 1
PRO_0000011779

Sites

Active site2951 By similarity

Amino acid modifications

Glycosylation221N-linked (GlcNAc...) Potential
Glycosylation751N-linked (GlcNAc...) Potential
Glycosylation2241N-linked (GlcNAc...) Potential
Glycosylation2671N-linked (GlcNAc...) Potential
Glycosylation3321N-linked (GlcNAc...) Potential
Glycosylation3391N-linked (GlcNAc...) Potential
Glycosylation3721N-linked (GlcNAc...) Potential
Glycosylation3891N-linked (GlcNAc...) Potential
Glycosylation4261N-linked (GlcNAc...) Potential
Glycosylation5441N-linked (GlcNAc...) Potential
Glycosylation5851N-linked (GlcNAc...) Potential
Glycosylation7391N-linked (GlcNAc...) Potential
Glycosylation7801N-linked (GlcNAc...) Potential
Glycosylation7901N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P22506 [UniParc].

Last modified August 1, 1991. Version 1.
Checksum: DBB4ABB9E4A32F1E

FASTA87696,231
        10         20         30         40         50         60 
MLMIVQLLVF ALGLAVAVPI QNYTQSPSQR DESSQWVSPH YYPTPQGGRL QDVWQEAYAR 

        70         80         90        100        110        120 
AKAIVGQMTI VEKVNLTTGT GWQLDPCVGN TGSVPRFGIP NLCLQDGPLG VRFADFVTGY 

       130        140        150        160        170        180 
PSGLATGATF NKDLFLQRGQ ALGHEFNSKG VHIALGPAVG PLGVKARGGR NFEAFGSDPY 

       190        200        210        220        230        240 
LQGTAAAATI KGLQENNVMA CVKHFIGNEQ EKYRQPDDIN PATNQTTKEA ISANIPDRAM 

       250        260        270        280        290        300 
HALYLWPFAD SVRAGVGSVM CSYNRVNNTY ACENSYMMNH LLKEELGFQG FVVSDWGAQL 

       310        320        330        340        350        360 
SGVYSAISGL DMSMPGEVYG GWNTGTSFWG QNLTKAIYNE TVPIERLDDM ATRILAALYA 

       370        380        390        400        410        420 
TNSFPTEDHL PNFSSWTTKE YGNKYYADNT TEIVKVNYNV DPSNDFTEDT ALKVAEESIV 

       430        440        450        460        470        480 
LLKNENNTLP ISPEKAKRLL LSGIAAGPDP IGYQCEDQSC TNGALFQGWG SGSVGSPKYQ 

       490        500        510        520        530        540 
VTPFEEISYL ARKNKMQFDY IRESYDLAQV TKVASDAHLS IVVVSAASGE GYITVDGNQG 

       550        560        570        580        590        600 
DRKNLTLWNN GDKLIETVAE NCANTVVVVT STGQINFEGF ADHPNVTAIV WAGPLGDRSG 

       610        620        630        640        650        660 
TAIANILFGK ANPSGHLPFT IAKTDDDYIP IETYSPSSGE PEDNHLVEND LLVDYRYFEE 

       670        680        690        700        710        720 
KNIEPRYAFG YGLSYNEYEV SNAKVSAAKK VDEELPEPAT YLSEFSYQNA KDSKNPSDAF 

       730        740        750        760        770        780 
APADLNRVNE YLYPYLDSNV TLKDGNYEYP DGYSTEQRTT PNQPGGGLGG NDALWEVAYN 

       790        800        810        820        830        840 
STDKFVPQGN STDKFVPQLY LKHPEDGKFE TPIQLRGFEK VELSPGEKKT VDLRLLRRDL 

       850        860        870 
SVWDTTRQSW IVESGTYEAL IGVAVNDIKT SVLFTI 

« Hide

References

[1]"Nucleotide sequences of Saccharomycopsis fibuligera genes for extracellular beta-glucosidases as expressed in Saccharomyces cerevisiae."
Machida M., Ohtsuki I., Fukui S., Yamashita I.
Appl. Environ. Microbiol. 54:3147-3155(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M22475 Genomic DNA. Translation: AAA34314.1.
PIRA45956.

3D structure databases

ProteinModelPortalP22506.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.
mycoCLAPBGL3A_SACFI.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGL1_SACFI
AccessionPrimary (citable) accession number: P22506
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 16, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries