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Protein

Beta-glucosidase B

Gene

bglB

Organism
Paenibacillus polymyxa (Bacillus polymyxa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei167Proton donorSequence analysis1
Active sitei356NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase B (EC:3.2.1.21)
Alternative name(s):
Amygdalase
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene namesi
Name:bglB
OrganismiPaenibacillus polymyxa (Bacillus polymyxa)
Taxonomic identifieri1406 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000638721 – 448Beta-glucosidase BAdd BLAST448

Structurei

Secondary structure

1448
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi13 – 17Combined sources5
Helixi20 – 23Combined sources4
Helixi36 – 40Combined sources5
Helixi48 – 50Combined sources3
Beta strandi53 – 55Combined sources3
Helixi59 – 71Combined sources13
Turni72 – 74Combined sources3
Beta strandi77 – 81Combined sources5
Helixi84 – 87Combined sources4
Helixi96 – 112Combined sources17
Beta strandi115 – 123Combined sources9
Helixi127 – 131Combined sources5
Helixi134 – 136Combined sources3
Helixi139 – 154Combined sources16
Beta strandi155 – 158Combined sources4
Beta strandi160 – 166Combined sources7
Helixi168 – 176Combined sources9
Beta strandi178 – 181Combined sources4
Helixi188 – 211Combined sources24
Beta strandi216 – 223Combined sources8
Beta strandi226 – 232Combined sources7
Helixi234 – 247Combined sources14
Helixi249 – 257Combined sources9
Helixi262 – 268Combined sources7
Helixi269 – 275Combined sources7
Helixi282 – 286Combined sources5
Beta strandi292 – 296Combined sources5
Beta strandi300 – 305Combined sources6
Beta strandi308 – 312Combined sources5
Beta strandi314 – 316Combined sources3
Beta strandi321 – 323Combined sources3
Helixi332 – 344Combined sources13
Turni345 – 349Combined sources5
Beta strandi352 – 357Combined sources6
Helixi373 – 389Combined sources17
Turni390 – 393Combined sources4
Beta strandi396 – 402Combined sources7
Helixi410 – 415Combined sources6
Beta strandi420 – 423Combined sources4
Turni425 – 427Combined sources3
Beta strandi430 – 432Combined sources3
Helixi434 – 445Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JIEX-ray2.30A2-448[»]
2O9PX-ray2.10A2-448[»]
2O9RX-ray2.30A4-448[»]
2O9TX-ray2.15A2-448[»]
2Z1SX-ray2.46A2-448[»]
ProteinModelPortaliP22505.
SMRiP22505.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP22505.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.Curated

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR03356. BGL. 1 hit.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22505-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENTFIFPA TFMWGTSTSS YQIEGGTDEG GRTPSIWDTF CQIPGKVIGG
60 70 80 90 100
DCGDVACDHF HHFKEDVQLM KQLGFLHYRF SVAWPRIMPA AGIINEEGLL
110 120 130 140 150
FYEHLLDEIE LAGLIPMLTL YHWDLPQWIE DEGGWTQRET IQHFKTYASV
160 170 180 190 200
IMDRFGERIN WWNTINEPYC ASILGYGTGE HAPGHENWRE AFTAAHHILM
210 220 230 240 250
CHGIASNLHK EKGLTGKIGI TLNMEHVDAA SERPEDVAAA IRRDGFINRW
260 270 280 290 300
FAEPLFNGKY PEDMVEWYGT YLNGLDFVQP GDMELIQQPG DFLGINYYTR
310 320 330 340 350
SIIRSTNDAS LLQVEQVHME EPVTDMGWEI HPESFYKLLT RIEKDFSKGL
360 370 380 390 400
PILITENGAA MRDELVNGQI EDTGRHGYIE EHLKACHRFI EEGGQLKGYF
410 420 430 440
VWSFLDNFEW AWGYSKRFGI VHINYETQER TPKQSALWFK QMMAKNGF
Length:448
Mass (Da):51,573
Last modified:August 1, 1991 - v1
Checksum:i628F44507C21EF1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60211 Genomic DNA. Translation: AAA22264.1.
PIRiJW0038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60211 Genomic DNA. Translation: AAA22264.1.
PIRiJW0038.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2JIEX-ray2.30A2-448[»]
2O9PX-ray2.10A2-448[»]
2O9RX-ray2.30A4-448[»]
2O9TX-ray2.15A2-448[»]
2Z1SX-ray2.46A2-448[»]
ProteinModelPortaliP22505.
SMRiP22505.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP22505.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR033132. Glyco_hydro_1_N_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR03356. BGL. 1 hit.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBGLB_PAEPO
AccessioniPrimary (citable) accession number: P22505
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: November 2, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.