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P22505

- BGLB_PAEPO

UniProt

P22505 - BGLB_PAEPO

Protein

Beta-glucosidase B

Gene

bglB

Organism
Paenibacillus polymyxa (Bacillus polymyxa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Aug 1991)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei167 – 1671Proton donorSequence Analysis
    Active sitei356 – 3561NucleophilePROSITE-ProRule annotation

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-glucosidase B (EC:3.2.1.21)
    Alternative name(s):
    Amygdalase
    Beta-D-glucoside glucohydrolase
    Cellobiase
    Gentiobiase
    Gene namesi
    Name:bglB
    OrganismiPaenibacillus polymyxa (Bacillus polymyxa)
    Taxonomic identifieri1406 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 448448Beta-glucosidase BPRO_0000063872Add
    BLAST

    Structurei

    Secondary structure

    1
    448
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi13 – 175
    Helixi20 – 234
    Helixi36 – 405
    Helixi48 – 503
    Beta strandi53 – 553
    Helixi59 – 7113
    Turni72 – 743
    Beta strandi77 – 815
    Helixi84 – 874
    Helixi96 – 11217
    Beta strandi115 – 1239
    Helixi127 – 1315
    Helixi134 – 1363
    Helixi139 – 15416
    Beta strandi155 – 1584
    Beta strandi160 – 1667
    Helixi168 – 1769
    Beta strandi178 – 1814
    Helixi188 – 21124
    Beta strandi216 – 2238
    Beta strandi226 – 2327
    Helixi234 – 24714
    Helixi249 – 2579
    Helixi262 – 2687
    Helixi269 – 2757
    Helixi282 – 2865
    Beta strandi292 – 2965
    Beta strandi300 – 3056
    Beta strandi308 – 3125
    Beta strandi314 – 3163
    Beta strandi321 – 3233
    Helixi332 – 34413
    Turni345 – 3495
    Beta strandi352 – 3576
    Helixi373 – 38917
    Turni390 – 3934
    Beta strandi396 – 4027
    Helixi410 – 4156
    Beta strandi420 – 4234
    Turni425 – 4273
    Beta strandi430 – 4323
    Helixi434 – 44512

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2JIEX-ray2.30A2-448[»]
    2O9PX-ray2.10A2-448[»]
    2O9RX-ray2.30A4-448[»]
    2O9TX-ray2.15A2-448[»]
    2Z1SX-ray2.46A2-448[»]
    ProteinModelPortaliP22505.
    SMRiP22505. Positions 4-448.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP22505.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.Curated

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR017736. Glyco_hydro_1_beta-glucosidase.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    TIGRFAMsiTIGR03356. BGL. 1 hit.
    PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P22505-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSENTFIFPA TFMWGTSTSS YQIEGGTDEG GRTPSIWDTF CQIPGKVIGG    50
    DCGDVACDHF HHFKEDVQLM KQLGFLHYRF SVAWPRIMPA AGIINEEGLL 100
    FYEHLLDEIE LAGLIPMLTL YHWDLPQWIE DEGGWTQRET IQHFKTYASV 150
    IMDRFGERIN WWNTINEPYC ASILGYGTGE HAPGHENWRE AFTAAHHILM 200
    CHGIASNLHK EKGLTGKIGI TLNMEHVDAA SERPEDVAAA IRRDGFINRW 250
    FAEPLFNGKY PEDMVEWYGT YLNGLDFVQP GDMELIQQPG DFLGINYYTR 300
    SIIRSTNDAS LLQVEQVHME EPVTDMGWEI HPESFYKLLT RIEKDFSKGL 350
    PILITENGAA MRDELVNGQI EDTGRHGYIE EHLKACHRFI EEGGQLKGYF 400
    VWSFLDNFEW AWGYSKRFGI VHINYETQER TPKQSALWFK QMMAKNGF 448
    Length:448
    Mass (Da):51,573
    Last modified:August 1, 1991 - v1
    Checksum:i628F44507C21EF1F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60211 Genomic DNA. Translation: AAA22264.1.
    PIRiJW0038.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60211 Genomic DNA. Translation: AAA22264.1 .
    PIRi JW0038.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2JIE X-ray 2.30 A 2-448 [» ]
    2O9P X-ray 2.10 A 2-448 [» ]
    2O9R X-ray 2.30 A 4-448 [» ]
    2O9T X-ray 2.15 A 2-448 [» ]
    2Z1S X-ray 2.46 A 2-448 [» ]
    ProteinModelPortali P22505.
    SMRi P22505. Positions 4-448.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P22505.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR017736. Glyco_hydro_1_beta-glucosidase.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    TIGRFAMsi TIGR03356. BGL. 1 hit.
    PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequences and homology analysis of two genes encoding beta-glucosidases from Bacillus polymyxa."
      Gonzalez-Candelas L., Ramon D., Polaina J.
      Gene 95:31-38(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiBGLB_PAEPO
    AccessioniPrimary (citable) accession number: P22505
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1991
    Last sequence update: August 1, 1991
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3