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P22505 (BGLB_PAEPO) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase B

EC=3.2.1.21
Alternative name(s):
Amygdalase
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene names
Name:bglB
OrganismPaenibacillus polymyxa (Bacillus polymyxa)
Taxonomic identifier1406 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Molecular functionGlycosidase
Hydrolase
   Technical term3D-structure
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Beta-glucosidase B
PRO_0000063872

Sites

Active site1671Proton donor Potential
Active site3561Nucleophile By similarity

Secondary structure

................................................................................ 448
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P22505 [UniParc].

Last modified August 1, 1991. Version 1.
Checksum: 628F44507C21EF1F

FASTA44851,573
        10         20         30         40         50         60 
MSENTFIFPA TFMWGTSTSS YQIEGGTDEG GRTPSIWDTF CQIPGKVIGG DCGDVACDHF 

        70         80         90        100        110        120 
HHFKEDVQLM KQLGFLHYRF SVAWPRIMPA AGIINEEGLL FYEHLLDEIE LAGLIPMLTL 

       130        140        150        160        170        180 
YHWDLPQWIE DEGGWTQRET IQHFKTYASV IMDRFGERIN WWNTINEPYC ASILGYGTGE 

       190        200        210        220        230        240 
HAPGHENWRE AFTAAHHILM CHGIASNLHK EKGLTGKIGI TLNMEHVDAA SERPEDVAAA 

       250        260        270        280        290        300 
IRRDGFINRW FAEPLFNGKY PEDMVEWYGT YLNGLDFVQP GDMELIQQPG DFLGINYYTR 

       310        320        330        340        350        360 
SIIRSTNDAS LLQVEQVHME EPVTDMGWEI HPESFYKLLT RIEKDFSKGL PILITENGAA 

       370        380        390        400        410        420 
MRDELVNGQI EDTGRHGYIE EHLKACHRFI EEGGQLKGYF VWSFLDNFEW AWGYSKRFGI 

       430        440 
VHINYETQER TPKQSALWFK QMMAKNGF 

« Hide

References

[1]"Sequences and homology analysis of two genes encoding beta-glucosidases from Bacillus polymyxa."
Gonzalez-Candelas L., Ramon D., Polaina J.
Gene 95:31-38(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M60211 Genomic DNA. Translation: AAA22264.1.
PIRJW0038.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2JIEX-ray2.30A2-448[»]
2O9PX-ray2.10A2-448[»]
2O9RX-ray2.30A4-448[»]
2O9TX-ray2.15A2-448[»]
2Z1SX-ray2.46A2-448[»]
ProteinModelPortalP22505.
SMRP22505. Positions 4-448.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR017736. Glyco_hydro_1_beta-glucosidase.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
TIGRFAMsTIGR03356. BGL. 1 hit.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP22505.

Entry information

Entry nameBGLB_PAEPO
AccessionPrimary (citable) accession number: P22505
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 16, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries