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Protein

Protein SAN1

Gene

SAN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a specific role in mating-type regulation of yeast, by acting post-translationally to control the stability or activity of the SIR4 proteins.

Miscellaneous

Present with 172 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri240 – 280RING-typePROSITE-ProRule annotationAdd BLAST41

GO - Molecular functioni

GO - Biological processi

  • nuclear protein quality control by the ubiquitin-proteasome system Source: SGD
  • protein polyubiquitination Source: GO_Central
  • response to misfolded protein Source: SGD
  • ubiquitin-dependent protein catabolic process Source: SGD

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-29740-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SAN1
Gene namesi
Name:SAN1
Ordered Locus Names:YDR143C
ORF Names:YD2943.02C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR143C
SGDiS000002550 SAN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000561621 – 610Protein SAN1Add BLAST610

Proteomic databases

MaxQBiP22470
PaxDbiP22470
PRIDEiP22470

PTM databases

CarbonylDBiP22470

Interactioni

Protein-protein interaction databases

BioGridi32197, 195 interactors
DIPiDIP-6517N
IntActiP22470, 28 interactors
MINTiP22470
STRINGi4932.YDR143C

Structurei

3D structure databases

ProteinModelPortaliP22470
SMRiP22470
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri240 – 280RING-typePROSITE-ProRule annotationAdd BLAST41

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiP22470
OMAiHIFGREC
OrthoDBiEOG092C1W5D

Family and domain databases

InterProiView protein in InterPro
IPR001841 Znf_RING
PfamiView protein in Pfam
PF13639 zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

P22470-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESGQEQNR GTNTSPNNAE NNNNSNAASG PLNGGAEQTR NITVSIQYSY
60 70 80 90 100
FTPERLAHLS NISNNDNNEN NSAASGSTIA NGTGPSFGIG NGGHQPDGAL
110 120 130 140 150
VLSFRDVPAS TPQDRLNSFI SVAAQLAMER FNRLLNRPKG ISKDEFDKLP
160 170 180 190 200
VLQVSDLPKA EGPLCSICYD EYEDEVDSTK AKRKRDSENE EESEGTKKRK
210 220 230 240 250
DNEGAPLRTT ADNDSNPSIT NATVVEPPSI PLTEQQRTLN DEETNPSYKH
260 270 280 290 300
SPIKLPCGHI FGRECIYKWS RLENSCPLCR QKISESVGVQ RAAQQDTDEV
310 320 330 340 350
AANEAAFERI RRVLYDPTAV NSTNENSSAP SENTSNTTVP TIGNASSGEQ
360 370 380 390 400
MLSRTGFFLV PQNGQPLHNP VRLPPNDSDR NGVNGPSSTT QNPPSNSGGS
410 420 430 440 450
NNNQSPRWVP IPLTLFQFHS PNPNPSASDS SASPSAANGP NSNNTSSDAT
460 470 480 490 500
DPHHNRLRAV LDHIFNVAQR GTSDTSATTA PGAQTVHNQG RNDSSSSDTT
510 520 530 540 550
QGSSFLENIS RLTGHFTNGS RDNNNDNNHS NDQQRGGSTG ENNRNNLFSS
560 570 580 590 600
GVASYRNQNG DVTTVELRNN NSAAFPPTDE NPSQGQGSSS SDTTIHNDVP
610
NDNNEQRSSQ
Length:610
Mass (Da):65,618
Last modified:August 1, 1991 - v1
Checksum:i15D9B5B1A8E3594E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X90585 Genomic DNA Translation: CAA62213.1
Z54139 Genomic DNA Translation: CAA90812.1
BK006938 Genomic DNA Translation: DAA11986.1
PIRiS05807
RefSeqiNP_010427.3, NM_001180450.3

Genome annotation databases

EnsemblFungiiYDR143C; YDR143C; YDR143C
GeneIDi851721
KEGGisce:YDR143C

Similar proteinsi

Entry informationi

Entry nameiSAN1_YEAST
AccessioniPrimary (citable) accession number: P22470
Secondary accession number(s): D6VSC6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: April 25, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health