P22416 (GST_SERMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Glutathione S-transferase GST-7.3 EC=2.5.1.18
Organism	Serratia marcescens
Taxonomic identifier	615 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length	31 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subunit structure	Homodimer.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the GST superfamily. Beta family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›31	›31	Glutathione S-transferase GST-7.3		PRO_0000185975
Experimental info
	Non-terminal residue	31	1

Sequences

	Sequence		Length	Mass (Da)
	P22416 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: AD993D56CD9AB0D5	FASTA	31	3,435
	10 20 30 MKLFYKAGAC SLSPHIVLRE LGLDFTAXKV D

References

[1]

"Purification and characterization of a novel glutathione transferase from Serratia marcescens." di Ilio C., Aceto A., Piccolomini R., Allocati N., Faraone A., Bucciarelli T., Barra D., Feferici G. Biochim. Biophys. Acta 1077:141-146(1991) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: CIP 6755.

Cross-references

Sequence databases
PIR	S14727.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
InterPro	IPR012336. Thioredoxin-like_fold. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GST_SERMA

Accession

Primary (citable) accession number: P22416

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	April 3, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program