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Protein

Chaperone protein dnaK2

Gene

dnaK2

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein dnaK2
Alternative name(s):
HSP70-2
Heat shock 70 kDa protein 2
Heat shock protein 70-2
Gene namesi
Name:dnaK2
Synonyms:dnaK
Ordered Locus Names:sll0170
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 636636Chaperone protein dnaK2PRO_0000078569Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei198 – 1981Phosphothreonine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP22358.

Expressioni

Inductioni

By stress conditions e.g. heat shock.

Interactioni

Protein-protein interaction databases

IntActiP22358. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP22358.
SMRiP22358. Positions 1-526.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

HOGENOMiHOG000228135.
InParanoidiP22358.
KOiK04043.
OMAiKLDCPAQ.
OrthoDBiEOG6JMMSV.
PhylomeDBiP22358.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22358-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVVGIDLG TTNSCVAVME GGKPTVIANA EGFRTTPSVV GYAKNGDRLV
60 70 80 90 100
GQIAKRQAVM NPGNTFYSVK RFIGRKFDEI TNEATEVAYS VVKDGNGNVK
110 120 130 140 150
LDCPAQGKQF APEEISAQVL RKLVDDASKY LGETVTQAVI TVPAYFNDSQ
160 170 180 190 200
RQATKDAGKI AGIEVLRIIN EPTAASLAYG LDKKDNETIL VFDLGGGTFD
210 220 230 240 250
VSILEVGEGV FEVLATSGDT HLGGDDFDKK IVDFLAGEFQ KAEGIDLRKD
260 270 280 290 300
KQALQRLTEA AEKAKIELSG VSQTEINLPF ITATQDGPKH LDTTLSRAKF
310 320 330 340 350
EEICSDLIDR CGIPVENAIR DAKIDKSALD EIVLVGGSTR IPAVQEVVKK
360 370 380 390 400
ILGKDPNQGV NPDEVVAVGA AIQGGVLSGE VKDILLLDVS PLSLGVETLG
410 420 430 440 450
GVMTKIIPRN TTIPTKKSET FSTAVDGQSN VEIHVLQGER EMANDNKSLG
460 470 480 490 500
TFRLDGIPPA PRGVPQIEVT FDIDANGILN VTAKDRGTGK EQSISITGAS
510 520 530 540 550
TLPDTEVDRM VKEAESNAAA DKERREKIDR KNQADSLVYQ AEKQITELGD
560 570 580 590 600
KVPAADKIKA EGLIKDLKEA VAQEDDAKIQ TVMPELQQVL YSIGSNMYQQ
610 620 630
AGAEAGVGAP GAGPEAGTSS GGGDDVIDAE FSEPEK
Length:636
Mass (Da):67,614
Last modified:August 1, 1991 - v1
Checksum:i33AE4CECBA28F40A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M57518 Genomic DNA. Translation: AAA27287.1.
BA000022 Genomic DNA. Translation: BAA10059.1.
PIRiC39025.

Genome annotation databases

EnsemblBacteriaiBAA10059; BAA10059; BAA10059.
KEGGisyn:sll0170.
PATRICi23841544. VBISynSp132158_2320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M57518 Genomic DNA. Translation: AAA27287.1.
BA000022 Genomic DNA. Translation: BAA10059.1.
PIRiC39025.

3D structure databases

ProteinModelPortaliP22358.
SMRiP22358. Positions 1-526.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP22358. 1 interaction.

Proteomic databases

PRIDEiP22358.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA10059; BAA10059; BAA10059.
KEGGisyn:sll0170.
PATRICi23841544. VBISynSp132158_2320.

Phylogenomic databases

HOGENOMiHOG000228135.
InParanoidiP22358.
KOiK04043.
OMAiKLDCPAQ.
OrthoDBiEOG6JMMSV.
PhylomeDBiP22358.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of the genes encoding two chaperone proteins of the cyanobacterium Synechocystis sp. PCC 6803."
    Chitnis P.R., Nelson N.
    J. Biol. Chem. 266:58-65(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome."
    Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S.
    DNA Res. 2:153-166(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27184 / PCC 6803 / N-1.
  3. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiDNAK2_SYNY3
AccessioniPrimary (citable) accession number: P22358
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: March 16, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.