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Protein

Sucrose porin

Gene

scrY

Organism
Salmonella typhimurium
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Porin for sucrose uptake.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Porin

Keywords - Biological processi

Ion transport, Sugar transport, Transport

Protein family/group databases

TCDBi1.B.3.1.2. the sugar porin (sp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sucrose porin
Gene namesi
Name:scrY
Encoded oniPlasmid pUR4000 Publication
OrganismiSalmonella typhimurium
Taxonomic identifieri90371 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 22221 PublicationAdd
BLAST
Chaini23 – 505483Sucrose porinPRO_0000025187Add
BLAST

Interactioni

Subunit structurei

Homotrimer.

Structurei

Secondary structure

1
505
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi95 – 10814Combined sources
Helixi122 – 1265Combined sources
Beta strandi138 – 15013Combined sources
Beta strandi156 – 16712Combined sources
Helixi175 – 1773Combined sources
Beta strandi181 – 19111Combined sources
Helixi197 – 1993Combined sources
Beta strandi203 – 2108Combined sources
Beta strandi215 – 2173Combined sources
Helixi218 – 2203Combined sources
Beta strandi222 – 2265Combined sources
Beta strandi228 – 23912Combined sources
Turni240 – 2423Combined sources
Beta strandi243 – 25513Combined sources
Beta strandi262 – 27514Combined sources
Beta strandi278 – 2869Combined sources
Helixi290 – 2923Combined sources
Beta strandi296 – 3016Combined sources
Beta strandi307 – 32115Combined sources
Beta strandi324 – 33815Combined sources
Helixi339 – 3413Combined sources
Beta strandi357 – 38933Combined sources
Beta strandi393 – 40614Combined sources
Beta strandi408 – 42518Combined sources
Helixi429 – 4313Combined sources
Beta strandi435 – 45117Combined sources
Beta strandi461 – 47111Combined sources
Helixi473 – 4775Combined sources
Beta strandi480 – 4834Combined sources
Beta strandi494 – 50411Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1A0SX-ray2.40P/Q/R93-505[»]
1A0TX-ray2.40P/Q/R93-505[»]
1OH2X-ray2.40P/R93-505[»]
Q93-503[»]
ProteinModelPortaliP22340.
SMRiP22340. Positions 93-505.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP22340.

Family & Domainsi

Domaini

The C-terminus helps to anchor the porin to the outer membrane.

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Family and domain databases

Gene3Di2.40.170.10. 1 hit.
InterProiIPR021570. LamB-type_porin_N_dom.
IPR003192. Porin_LamB.
[Graphical view]
PfamiPF02264. LamB. 1 hit.
PF11471. Sugarporin_N. 1 hit.
[Graphical view]
ProDomiPD008788. Porin_LamB. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P22340-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRKSTLAML IALLTSAASA HAQTDISTIE ARLNALEKRL QEAENRAQTA
60 70 80 90 100
ENRAGAAEKK VQQLTAQQQK NQNSTQEVAQ RTARLEKKAD DKSGFEFHGY
110 120 130 140 150
ARSGVIMNDS GASTKSGAYI TPAGETGGAI GRLGNQADTY VEMNLEHKQT
160 170 180 190 200
LDNGATTRFK VMVADGQTSY NDWTASTSDL NVRQAFVELG NLPTFAGPFK
210 220 230 240 250
GSTLWAGKRF DRDNFDIHWI DSDVVFLAGT GGGIYDVKWN DGLRSNFSLY
260 270 280 290 300
GRNFGDIDDS SNSVQNYILT MNHFAGPLQM MVSGLRAKDN DERKDSNGNL
310 320 330 340 350
AKGDAANTGV HALLGLHNDS FYGLRDGSSK TALLYGHGLG AEVKGIGSDG
360 370 380 390 400
ALRPGADTWR IASYGTTPLS ENWSVAPAML AQRSKDRYAD GDSYQWATFN
410 420 430 440 450
LRLIQAINQN FALAYEGSYQ YMDLKPEGYN DRQAVNGSFY KLTFAPTFKV
460 470 480 490 500
GSIGDFFSRP EIRFYTSWMD WSKKLNNYAS DDALGSDGFN SGGEWSFGVQ

METWF
Length:505
Mass (Da):55,467
Last modified:August 1, 1991 - v1
Checksum:iDD37733EC22A2135
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38416 Genomic DNA. Translation: AAA98417.1.
X57400 Genomic DNA. Translation: CAA40656.1.
PIRiA39127.
S15193.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M38416 Genomic DNA. Translation: AAA98417.1.
X57400 Genomic DNA. Translation: CAA40656.1.
PIRiA39127.
S15193.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1A0SX-ray2.40P/Q/R93-505[»]
1A0TX-ray2.40P/Q/R93-505[»]
1OH2X-ray2.40P/R93-505[»]
Q93-503[»]
ProteinModelPortaliP22340.
SMRiP22340. Positions 93-505.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi1.B.3.1.2. the sugar porin (sp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP22340.

Family and domain databases

Gene3Di2.40.170.10. 1 hit.
InterProiIPR021570. LamB-type_porin_N_dom.
IPR003192. Porin_LamB.
[Graphical view]
PfamiPF02264. LamB. 1 hit.
PF11471. Sugarporin_N. 1 hit.
[Graphical view]
ProDomiPD008788. Porin_LamB. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Plasmid-mediated sucrose metabolism in Escherichia coli: characterization of scrY, the structural gene for a phosphoenolpyruvate-dependent sucrose phosphotransferase system outer membrane porin."
    Hardesty C., Ferran C., DiRienzo J.M.
    J. Bacteriol. 173:449-456(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 23-33.
    Strain: 6153-62.
  2. "A sugar-specific porin, ScrY, is involved in sucrose uptake in enteric bacteria."
    Schmid K., Ebner R., Jahreis K., Lengeler J.W., Titgemeyer F.
    Mol. Microbiol. 5:941-950(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose."
    Forst D., Welte W., Wacker T., Diederichs K.
    Nat. Struct. Biol. 5:37-46(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).

Entry informationi

Entry nameiSCRY_SALTM
AccessioniPrimary (citable) accession number: P22340
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Plasmid

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.