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P22237

- NDUS3_DICDI

UniProt

P22237 - NDUS3_DICDI

Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

nad9

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Aug 1991)
      Previous versions | rss
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    Functioni

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.By similarity

    Catalytic activityi

    NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
    NADH + acceptor = NAD+ + reduced acceptor.

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
    Gene namesi
    Name:nad9
    Synonyms:ndufs3, noxA
    ORF Names:DDB_G0294032
    Encoded oniMitochondrion
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Mitochondrion

    Organism-specific databases

    dictyBaseiDDB_G0294032. nad9.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: UniProtKB-SubCell
    2. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 209209NADH-ubiquinone oxidoreductase subunit 9PRO_0000118645Add
    BLAST

    Interactioni

    Subunit structurei

    Complex I is composed of about 45 different subunits.By similarity

    Protein-protein interaction databases

    STRINGi44689.DidioMp17.

    Structurei

    3D structure databases

    ProteinModelPortaliP22237.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I 30 kDa subunit family.Curated

    Phylogenomic databases

    eggNOGiCOG0852.
    KOiK03936.
    OMAiVECENHT.
    PhylomeDBiP22237.

    Family and domain databases

    HAMAPiMF_01357. NDH1_NuoC.
    InterProiIPR010218. NADH_DH_suC.
    IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
    IPR020396. NADH_UbQ_OxRdtase_CS.
    [Graphical view]
    PfamiPF00329. Complex1_30kDa. 1 hit.
    [Graphical view]
    ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    PROSITEiPS00542. COMPLEX1_30K. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P22237-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKDYKNELKV KINLGEHLRL SIPGLVKKIM YKTHYLEIQV EKEKMLTVLK    50
    YLKEASKYQC NMLLDIVCVD CLNIEEIKIG RFKLIYVLNS IYNNTRVHLS 100
    TYVENNGIIE TTSGLFESSV WLEREIWDMF GIYFEKHPDL RRILTDYGFV 150
    GYPLKKDFPI TGYLEVYYDV NDKKIIYKPI ELMQEYRNYN FGAVWGDYER 200
    KVYLENIIK 209
    Length:209
    Mass (Da):25,033
    Last modified:August 1, 1991 - v1
    Checksum:iA22D482B71B38374
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52680 Genomic DNA. Translation: CAA36903.1.
    AB000109 Genomic DNA. Translation: BAA78066.1.
    PIRiS12247.
    RefSeqiNP_050084.1. NC_000895.1.

    Genome annotation databases

    GeneIDi2193912.
    KEGGiddi:DidioMp17.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52680 Genomic DNA. Translation: CAA36903.1 .
    AB000109 Genomic DNA. Translation: BAA78066.1 .
    PIRi S12247.
    RefSeqi NP_050084.1. NC_000895.1.

    3D structure databases

    ProteinModelPortali P22237.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 44689.DidioMp17.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2193912.
    KEGGi ddi:DidioMp17.

    Organism-specific databases

    dictyBasei DDB_G0294032. nad9.

    Phylogenomic databases

    eggNOGi COG0852.
    KOi K03936.
    OMAi VECENHT.
    PhylomeDBi P22237.

    Miscellaneous databases

    PROi P22237.

    Family and domain databases

    HAMAPi MF_01357. NDH1_NuoC.
    InterProi IPR010218. NADH_DH_suC.
    IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
    IPR020396. NADH_UbQ_OxRdtase_CS.
    [Graphical view ]
    Pfami PF00329. Complex1_30kDa. 1 hit.
    [Graphical view ]
    ProDomi PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    PROSITEi PS00542. COMPLEX1_30K. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "ORF209 of Dictyostelium discoideum mitochondrial DNA has a homologue in chloroplast DNA."
      Tanaka Y., Kuroe K., Angata K., Yanagisawa K.
      Plant Mol. Biol. 15:659-660(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization."
      Ogawa S., Yoshino R., Angata K., Iwamoto M., Pi M., Kuroe K., Matsuo K., Morio T., Urushihara H., Yanagisawa K., Tanaka Y.
      Mol. Gen. Genet. 263:514-519(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX3.

    Entry informationi

    Entry nameiNDUS3_DICDI
    AccessioniPrimary (citable) accession number: P22237
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1991
    Last sequence update: August 1, 1991
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3