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P22237 (NDUS3_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH-ubiquinone oxidoreductase subunit 9

EC=1.6.5.3
EC=1.6.99.3
Gene names
Name:nad9
Synonyms:ndufs3, noxA
ORF Names:DDB_G0294032
Encoded onMitochondrion
OrganismDictyostelium discoideum (Slime mold) [Reference proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.

Catalytic activity

NADH + ubiquinone = NAD+ + ubiquinol.

NADH + acceptor = NAD+ + reduced acceptor.

Subunit structure

Complex I is composed of about 45 different subunits By similarity.

Subcellular location

Mitochondrion inner membrane By similarity.

Sequence similarities

Belongs to the complex I 30 kDa subunit family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 209209NADH-ubiquinone oxidoreductase subunit 9
PRO_0000118645

Sequences

Sequence LengthMass (Da)Tools
P22237 [UniParc].

Last modified August 1, 1991. Version 1.
Checksum: A22D482B71B38374

FASTA20925,033
        10         20         30         40         50         60 
MKDYKNELKV KINLGEHLRL SIPGLVKKIM YKTHYLEIQV EKEKMLTVLK YLKEASKYQC 

        70         80         90        100        110        120 
NMLLDIVCVD CLNIEEIKIG RFKLIYVLNS IYNNTRVHLS TYVENNGIIE TTSGLFESSV 

       130        140        150        160        170        180 
WLEREIWDMF GIYFEKHPDL RRILTDYGFV GYPLKKDFPI TGYLEVYYDV NDKKIIYKPI 

       190        200 
ELMQEYRNYN FGAVWGDYER KVYLENIIK 

« Hide

References

« Hide 'large scale' references
[1]"ORF209 of Dictyostelium discoideum mitochondrial DNA has a homologue in chloroplast DNA."
Tanaka Y., Kuroe K., Angata K., Yanagisawa K.
Plant Mol. Biol. 15:659-660(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization."
Ogawa S., Yoshino R., Angata K., Iwamoto M., Pi M., Kuroe K., Matsuo K., Morio T., Urushihara H., Yanagisawa K., Tanaka Y.
Mol. Gen. Genet. 263:514-519(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX3.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X52680 Genomic DNA. Translation: CAA36903.1.
AB000109 Genomic DNA. Translation: BAA78066.1.
PIRS12247.
RefSeqNP_050084.1. NC_000895.1.

3D structure databases

ProteinModelPortalP22237.
ModBaseSearch...

Protein-protein interaction databases

STRING44689.DidioMp17.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2193912.
KEGGddi:DidioMp17.

Organism-specific databases

dictyBaseDDB_G0294032. nad9.

Phylogenomic databases

eggNOGCOG0852.
KOK03936.
OMAVECENHT.

Family and domain databases

InterProIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNDUS3_DICDI
AccessionPrimary (citable) accession number: P22237
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: May 1, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

SIMILARITY comments

Index of protein domains and families