Reviewed,
UniProtKB/Swiss-Prot P22237 (NDUS3_DICDI)
Last modified
June 16, 2009.
Version 66.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: NADH-ubiquinone oxidoreductase subunit 9 EC=1.6.5.3 EC=1.6.99.3 | ||||||
| Gene names |
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| Encoded on | Mitochondrion | ||||||
| Organism | Dictyostelium discoideum (Slime mold) [Complete proteome] | ||||||
| Taxonomic identifier | 44689 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium |
Protein attributes
| Sequence length | 209 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. |
| Catalytic activity | NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor. |
| Subunit structure | Complex I is composed of about 45 different subunits By similarity. |
| Subcellular location | Mitochondrion inner membrane By similarity. |
| Sequence similarities | Belongs to the complex I 30 kDa subunit family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Membrane Mitochondrion Mitochondrion inner membrane |
| Ligand | NAD Ubiquinone |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chainInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 209 | 209 | NADH-ubiquinone oxidoreductase subunit 9 | PRO_0000118645 | |||
Sequences
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References
| [1] | "ORF209 of Dictyostelium discoideum mitochondrial DNA has a homologue in chloroplast DNA." Tanaka Y., Kuroe K., Angata K., Yanagisawa K. Plant Mol. Biol. 15:659-660(1990) [PubMed: 2102381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization." Ogawa S., Yoshino R., Angata K., Iwamoto M., Pi M., Kuroe K., Matsuo K., Morio T., Urushihara H., Yanagisawa K., Tanaka Y. Mol. Gen. Genet. 263:514-519(2000) [PubMed: 10821186] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: AX3. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| X52680 Genomic DNA. Translation: CAA36903.1. AB000109 Genomic DNA. Translation: BAA78066.1. | |
| PIR | S12247. |
| RefSeq | NP_050084.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2193912. |
Organism-specific databases | |
| dictyBase | DDB_G0294032. nad9. |
Enzyme and pathway databases | |
| BRENDA | 1.6.5.3. 424. 1.6.99.3. 424. |
Family and domain databases | |
| InterPro | IPR001268. NADH_UbQ_OxRdtase_30kDa_su. [Graphical view] |
| Pfam | PF00329. Complex1_30kDa. 1 hit. [Graphical view] |
| ProDom | PD001581. Complex1_30K. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| PROSITE | PS00542. COMPLEX1_30K. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NDUS3_DICDI | ||||||||
| Accession | Primary (citable) accession number: P22237 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Dictyostelium discoideum Dictyostelium discoideum: entries, gene names and cross-references to dictyBase |
| SIMILARITY comments Index of protein domains and families |

Clusters with


