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Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

nad9

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Respiratory chain, Transport
LigandNAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Gene namesi
Name:nad9
Synonyms:ndufs3, noxA
ORF Names:DDB_G0294032
Encoded oniMitochondrion
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componenti: Mitochondrion

Organism-specific databases

dictyBaseiDDB_G0294032 nad9

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001186451 – 209NADH-ubiquinone oxidoreductase subunit 9Add BLAST209

Interactioni

Subunit structurei

Complex I is composed of about 45 different subunits.By similarity

Structurei

3D structure databases

ProteinModelPortaliP22237
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Phylogenomic databases

InParanoidiP22237
KOiK03936
OMAiVFPAANW
PhylomeDBiP22237

Family and domain databases

Gene3Di3.30.460.80, 1 hit
HAMAPiMF_01357 NDH1_NuoC, 1 hit
InterProiView protein in InterPro
IPR010218 NADH_DH_suC
IPR037232 NADH_quin_OxRdtase_su_C/D-like
IPR001268 NADH_UbQ_OxRdtase_30kDa_su
IPR020396 NADH_UbQ_OxRdtase_CS
PfamiView protein in Pfam
PF00329 Complex1_30kDa, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581 NADH_UbQ_OxRdtase_30kDa_su, 1 hit
SUPFAMiSSF143243 SSF143243, 1 hit
PROSITEiView protein in PROSITE
PS00542 COMPLEX1_30K, 1 hit

Sequencei

Sequence statusi: Complete.

P22237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDYKNELKV KINLGEHLRL SIPGLVKKIM YKTHYLEIQV EKEKMLTVLK
60 70 80 90 100
YLKEASKYQC NMLLDIVCVD CLNIEEIKIG RFKLIYVLNS IYNNTRVHLS
110 120 130 140 150
TYVENNGIIE TTSGLFESSV WLEREIWDMF GIYFEKHPDL RRILTDYGFV
160 170 180 190 200
GYPLKKDFPI TGYLEVYYDV NDKKIIYKPI ELMQEYRNYN FGAVWGDYER

KVYLENIIK
Length:209
Mass (Da):25,033
Last modified:August 1, 1991 - v1
Checksum:iA22D482B71B38374
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52680 Genomic DNA Translation: CAA36903.1
AB000109 Genomic DNA Translation: BAA78066.1
PIRiS12247
RefSeqiNP_050084.1, NC_000895.1

Genome annotation databases

GeneIDi2193912
KEGGiddi:DidioMp17

Similar proteinsi

Entry informationi

Entry nameiNDUS3_DICDI
AccessioniPrimary (citable) accession number: P22237
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health