Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

nad9

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Gene namesi
Name:nad9
Synonyms:ndufs3, noxA
ORF Names:DDB_G0294032
Encoded oniMitochondrion
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195 Componenti: Mitochondrion

Organism-specific databases

dictyBaseiDDB_G0294032. nad9.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209NADH-ubiquinone oxidoreductase subunit 9PRO_0000118645Add
BLAST

Interactioni

Subunit structurei

Complex I is composed of about 45 different subunits.By similarity

Protein-protein interaction databases

STRINGi44689.DidioMp17.

Structurei

3D structure databases

ProteinModelPortaliP22237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Phylogenomic databases

eggNOGiCOG0852.
InParanoidiP22237.
KOiK03936.
OMAiYEPVEYA.
PhylomeDBiP22237.

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDYKNELKV KINLGEHLRL SIPGLVKKIM YKTHYLEIQV EKEKMLTVLK
60 70 80 90 100
YLKEASKYQC NMLLDIVCVD CLNIEEIKIG RFKLIYVLNS IYNNTRVHLS
110 120 130 140 150
TYVENNGIIE TTSGLFESSV WLEREIWDMF GIYFEKHPDL RRILTDYGFV
160 170 180 190 200
GYPLKKDFPI TGYLEVYYDV NDKKIIYKPI ELMQEYRNYN FGAVWGDYER

KVYLENIIK
Length:209
Mass (Da):25,033
Last modified:August 1, 1991 - v1
Checksum:iA22D482B71B38374
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52680 Genomic DNA. Translation: CAA36903.1.
AB000109 Genomic DNA. Translation: BAA78066.1.
PIRiS12247.
RefSeqiNP_050084.1. NC_000895.1.

Genome annotation databases

GeneIDi2193912.
KEGGiddi:DidioMp17.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52680 Genomic DNA. Translation: CAA36903.1.
AB000109 Genomic DNA. Translation: BAA78066.1.
PIRiS12247.
RefSeqiNP_050084.1. NC_000895.1.

3D structure databases

ProteinModelPortaliP22237.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DidioMp17.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2193912.
KEGGiddi:DidioMp17.

Organism-specific databases

dictyBaseiDDB_G0294032. nad9.

Phylogenomic databases

eggNOGiCOG0852.
InParanoidiP22237.
KOiK03936.
OMAiYEPVEYA.
PhylomeDBiP22237.

Miscellaneous databases

PROiP22237.

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "ORF209 of Dictyostelium discoideum mitochondrial DNA has a homologue in chloroplast DNA."
    Tanaka Y., Kuroe K., Angata K., Yanagisawa K.
    Plant Mol. Biol. 15:659-660(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The mitochondrial DNA of Dictyostelium discoideum: complete sequence, gene content and genome organization."
    Ogawa S., Yoshino R., Angata K., Iwamoto M., Pi M., Kuroe K., Matsuo K., Morio T., Urushihara H., Yanagisawa K., Tanaka Y.
    Mol. Gen. Genet. 263:514-519(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX3.

Entry informationi

Entry nameiNDUS3_DICDI
AccessioniPrimary (citable) accession number: P22237
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: May 27, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.