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Protein

Serine/threonine-protein phosphatase PP1

Gene

PP1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611Manganese 1By similarity
Metal bindingi63 – 631Manganese 1By similarity
Metal bindingi89 – 891Manganese 1By similarity
Metal bindingi89 – 891Manganese 2By similarity
Metal bindingi121 – 1211Manganese 2By similarity
Active sitei122 – 1221Proton donorBy similarity
Metal bindingi170 – 1701Manganese 2By similarity
Metal bindingi245 – 2451Manganese 2By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
Gene namesi
Name:PP1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea
ProteomesiUP000007305 Componenti: Chromosome 4

Organism-specific databases

GrameneiP22198.
MaizeGDBi30136.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316Serine/threonine-protein phosphatase PP1PRO_0000058808Add
BLAST

Proteomic databases

PRIDEiP22198.

Expressioni

Gene expression databases

ExpressionAtlasiP22198. baseline.

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G112240_P02.

Structurei

3D structure databases

ProteinModelPortaliP22198.
SMRiP22198. Positions 6-298.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

HOGENOMiHOG000172697.
KOiK06269.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22198-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPALLDDVI RRLLEVKNLK PGKNAQLSES EIKQLCAAAK EIFLQQPNLL
60 70 80 90 100
ELEAPIKICG DVHGQYSDLL RLFDYGGYPP QANYLFLGDY VDRGKQSLET
110 120 130 140 150
ICLLLAYKVK YPENFFLLRG NHECASVNRI YGFYDECKRR FSVKLWKTFT
160 170 180 190 200
DCFNCLPVSA LIDEKILCMH GGLSPELNKL EQILNLNRPT DVPDTGLLCD
210 220 230 240 250
LLWSDPSNEA TGWAINDRGV SFTFGPDKVS EFLEKHDLDL ICRAHQVVED
260 270 280 290 300
GYEFFASRQL VTIFSAPNYC GEFDNAGAMM SVDDTLMCSF QILKPARKMM
310
GGSTNNKSGF KSFRGW
Length:316
Mass (Da):35,763
Last modified:August 1, 1991 - v1
Checksum:iED71EB1ABF308680
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60215 mRNA. Translation: AAA33545.1.
PIRiS29317.
RefSeqiNP_001105341.1. NM_001111871.1.
UniGeneiZm.93920.

Genome annotation databases

EnsemblPlantsiGRMZM2G112240_T01; GRMZM2G112240_P01; GRMZM2G112240.
GeneIDi542269.
KEGGizma:542269.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60215 mRNA. Translation: AAA33545.1.
PIRiS29317.
RefSeqiNP_001105341.1. NM_001111871.1.
UniGeneiZm.93920.

3D structure databases

ProteinModelPortaliP22198.
SMRiP22198. Positions 6-298.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4577.GRMZM2G112240_P02.

Proteomic databases

PRIDEiP22198.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiGRMZM2G112240_T01; GRMZM2G112240_P01; GRMZM2G112240.
GeneIDi542269.
KEGGizma:542269.

Organism-specific databases

GrameneiP22198.
MaizeGDBi30136.

Phylogenomic databases

HOGENOMiHOG000172697.
KOiK06269.

Gene expression databases

ExpressionAtlasiP22198. baseline.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Smith R.D., Walker J.C.
    Submitted (AUG-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiPP1_MAIZE
AccessioniPrimary (citable) accession number: P22198
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: June 24, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.