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Protein

Serine/threonine-protein phosphatase PP1

Gene

PP1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Manganese 1By similarity1
Metal bindingi63Manganese 1By similarity1
Metal bindingi89Manganese 1By similarity1
Metal bindingi89Manganese 2By similarity1
Metal bindingi121Manganese 2By similarity1
Active sitei122Proton donorBy similarity1
Metal bindingi170Manganese 2By similarity1
Metal bindingi245Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
Gene namesi
Name:PP1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi30136

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000588081 – 316Serine/threonine-protein phosphatase PP1Add BLAST316

Proteomic databases

PaxDbiP22198
PRIDEiP22198

Expressioni

Gene expression databases

ExpressionAtlasiP22198 baseline and differential
GenevisibleiP22198 ZM

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G112240_P02

Structurei

3D structure databases

ProteinModelPortaliP22198
SMRiP22198
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Phylogenomic databases

eggNOGiENOG410IN85 Eukaryota
ENOG410XPVF LUCA
HOGENOMiHOG000172697
KOiK06269

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
IPR031675 STPPase_N
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF16891 STPPase_N, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P22198-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPALLDDVI RRLLEVKNLK PGKNAQLSES EIKQLCAAAK EIFLQQPNLL
60 70 80 90 100
ELEAPIKICG DVHGQYSDLL RLFDYGGYPP QANYLFLGDY VDRGKQSLET
110 120 130 140 150
ICLLLAYKVK YPENFFLLRG NHECASVNRI YGFYDECKRR FSVKLWKTFT
160 170 180 190 200
DCFNCLPVSA LIDEKILCMH GGLSPELNKL EQILNLNRPT DVPDTGLLCD
210 220 230 240 250
LLWSDPSNEA TGWAINDRGV SFTFGPDKVS EFLEKHDLDL ICRAHQVVED
260 270 280 290 300
GYEFFASRQL VTIFSAPNYC GEFDNAGAMM SVDDTLMCSF QILKPARKMM
310
GGSTNNKSGF KSFRGW
Length:316
Mass (Da):35,763
Last modified:August 1, 1991 - v1
Checksum:iED71EB1ABF308680
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60215 mRNA Translation: AAA33545.1
PIRiS29317
RefSeqiNP_001105341.1, NM_001111871.1
UniGeneiZm.93920

Genome annotation databases

GeneIDi542269
KEGGizma:542269

Similar proteinsi

Entry informationi

Entry nameiPP1_MAIZE
AccessioniPrimary (citable) accession number: P22198
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health