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P22193 (RAD1_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA damage checkpoint control protein rad1
Gene names
Name:rad1
ORF Names:SPAC1952.07
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recombinational reparation of DNA damages induced by UV and gamma radiation.

Subcellular location

Nucleus Potential.

Sequence similarities

Belongs to the rad1 family.

Sequence caution

The sequence AAA35329.1 differs from that shown. Reason: Erroneous gene model prediction.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

myh1Q101592EBI-767637,EBI-767574

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 323323DNA damage checkpoint control protein rad1
PRO_0000097151

Regions

Compositional bias285 – 32339Asp/Glu-rich (acidic)
Compositional bias285 – 29410Glu-rich (acidic)

Sequences

Sequence LengthMass (Da)Tools
P22193 [UniParc].

Last modified June 1, 1994. Version 2.
Checksum: 1A2A4DEFC3A55EE6

FASTA32336,528
        10         20         30         40         50         60 
MFQAETVCLK QIQSTLRCID FSKECTIEIT SRGLRFAVEE SQSLQAHAFL DKSLFQTFNF 

        70         80         90        100        110        120 
QGDSDGDTYM FQTMISPLLQ SLSIYTDGKE RISTSAWDQP TVNIMHKRGV ICKVQYNGPG 

       130        140        150        160        170        180 
CPFIWEVEEM AGYATACELL TMECEDDVDI NRLASTLCTK IIMKSNWLYD ALVELDNNMG 

       190        200        210        220        230        240 
ENLIIHTSSQ KSTFLLRCVG ALSTTEIEYP NEKSVLESFE TDSENTYSYR FSLIRHALKA 

       250        260        270        280        290        300 
LQVGSKVNLR IDENGTLSIQ IMLVGQEGLC TFVDFCIVPL DLVSEDEEED EEEEPAESNQ 

       310        320 
SDNNVLRNDP NYRGDAETED EDS

« Hide

References

« Hide 'large scale' references
[1]"Cloning and analysis of a gene involved in DNA repair and recombination, the rad1 gene of Schizosaccharomyces pombe."
Sunnerhagen P., Seaton B.L., Nasim A., Subramani S.
Mol. Cell. Biol. 10:3750-3760(1990) [PubMed: 2355921] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Fission yeast gene structure and recognition."
Zhang M.Q., Marr T.G.
Nucleic Acids Res. 22:1750-1759(1994) [PubMed: 8202381] [Abstract]
Cited for: SEQUENCE REVISION.
[3]"The Schizosaccharomyces pombe rad1 gene consists of three exons and the cDNA sequence is partially homologous to the Ustilago maydis REC1 cDNA."
Long K.E., Sunnerhagen P., Subramani S.
Gene 148:155-159(1994) [PubMed: 7926829] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: 972 / ATCC 24843.
[4]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M38132 Genomic DNA. Translation: AAA35329.1. Sequence problems.
Z28385 mRNA. Translation: CAA82231.1.
CU329670 Genomic DNA. Translation: CAB52571.1.
PIRJC2578.
RefSeqNP_594809.1. NM_001020238.1.

3D structure databases

ProteinModelPortalP22193.
ModBaseSearch...

Protein-protein interaction databases

IntActP22193. 1 interaction.
MINTMINT-1209745.
STRINGP22193.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC1952.07.1; SPAC1952.07.1:pep; SPAC1952.07.
GeneID2542558.
GenomeReviewsGene locus rad1 in contig CU329670_GR.
KEGGspo:SPAC1952.07.
NMPDRfig|4896.1.peg.4779.

Organism-specific databases

GeneDB_SpombeSPAC1952.07.

Phylogenomic databases

eggNOGfuNOG04822.
GeneTreeEFGT00050000003457.
OMAEIGCKEC.
OrthoDBEOG405W98.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-002883-MONOMER.

Gene expression databases

ArrayExpressP22193.

Family and domain databases

InterProIPR003021. Rad1_Rec1.
IPR003011. Rad1_repair.
[Graphical view]
KOK02830.
PANTHERPTHR10870. Rad1_Rec1. 1 hit.
PfamPF02144. Rad1. 1 hit.
[Graphical view]
PRINTSPR01245. RAD1REC1.
PR01246. RAD1REPAIR.
ProtoNetSearch...

Entry information

Entry nameRAD1_SCHPO
AccessionPrimary (citable) accession number: P22193
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: June 1, 1994
Last modified: December 14, 2011
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

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