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P22166 (MCP_IRV22) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Major capsid protein

Short name=MCP
Alternative name(s):
P50
Gene names
Name:MCP
OrganismSimulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Taxonomic identifier10489 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostSimulium [TaxID: 7191]

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass By similarity.

Subunit structure

Homotrimer By similarity.

Subcellular location

Virion Potential.

Post-translational modification

The N-terminus is blocked.

Sequence similarities

Belongs to the NCLDV major capsid protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
Virion
   Developmental stageLate protein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentviral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 472472Major capsid protein
PRO_0000222384

Sequences

Sequence LengthMass (Da)Tools
P22166 [UniParc].

Last modified August 1, 1991. Version 1.
Checksum: B3D81F790AE9EFE9

FASTA47251,993
        10         20         30         40         50         60 
MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV PLSRNTGNAA 

        70         80         90        100        110        120 
FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL RWTKNLMHNL IREATITFND 

       130        140        150        160        170        180 
LVAARFDNYH LDFWSAFTVP ASKRNGYDNM IGNVSSLINP VAPGGTLGSV GGINLNLPLP 

       190        200        210        220        230        240 
FFFSRDTGVA LPTAALPYNE MQINFNFRDW HELLILTNSA LVPPASSYVS IVVGTHISAA 

       250        260        270        280        290        300 
PVLGPVQVWA NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA 

       310        320        330        340        350        360 
IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY ENTNRLGAMG 

       370        380        390        400        410        420 
SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST NYGKLTNVFV VPAASSAAIS 

       430        440        450        460        470 
AAGGTGGQAG SDYAQSYEFV IVAVNNNIVR IENSLVRNRR RWSREGPMVM VC 

« Hide

References

[1]"Identification and characterization of the gene encoding the major structural protein of insect iridescent virus type 22."
Cameron I.R.
Virology 178:35-42(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M32799 Genomic DNA. Translation: AAA66585.1.
PIRVCXFSI. B37075.

3D structure databases

ProteinModelPortalP22166.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMSSF49749. SSF49749. 2 hits.
ProtoNetSearch...

Entry information

Entry nameMCP_IRV22
AccessionPrimary (citable) accession number: P22166
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 16, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families