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P22166

- MCP_IRV22

UniProt

P22166 - MCP_IRV22

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Protein
Major capsid protein
Gene
MCP
Organism
Simulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass By similarity.

GO - Molecular functioni

  1. structural molecule activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein
Short name:
MCP
Alternative name(s):
P50
Gene namesi
Name:MCP
OrganismiSimulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Taxonomic identifieri10489 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiSimulium [TaxID: 7191]

Subcellular locationi

Virion Reviewed prediction

GO - Cellular componenti

  1. viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 472472Major capsid protein
PRO_0000222384Add
BLAST

Post-translational modificationi

The N-terminus is blocked.

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Homotrimer By similarity.

Structurei

3D structure databases

ProteinModelPortaliP22166.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.

Sequencei

Sequence statusi: Complete.

P22166-1 [UniParc]FASTAAdd to Basket

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MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV    50
PLSRNTGNAA FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL 100
RWTKNLMHNL IREATITFND LVAARFDNYH LDFWSAFTVP ASKRNGYDNM 150
IGNVSSLINP VAPGGTLGSV GGINLNLPLP FFFSRDTGVA LPTAALPYNE 200
MQINFNFRDW HELLILTNSA LVPPASSYVS IVVGTHISAA PVLGPVQVWA 250
NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA 300
IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY 350
ENTNRLGAMG SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST 400
NYGKLTNVFV VPAASSAAIS AAGGTGGQAG SDYAQSYEFV IVAVNNNIVR 450
IENSLVRNRR RWSREGPMVM VC 472
Length:472
Mass (Da):51,993
Last modified:August 1, 1991 - v1
Checksum:iB3D81F790AE9EFE9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M32799 Genomic DNA. Translation: AAA66585.1.
PIRiB37075. VCXFSI.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M32799 Genomic DNA. Translation: AAA66585.1 .
PIRi B37075. VCXFSI.

3D structure databases

ProteinModelPortali P22166.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProi IPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view ]
Pfami PF04451. Capsid_NCLDV. 1 hit.
[Graphical view ]
SUPFAMi SSF49749. SSF49749. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of the gene encoding the major structural protein of insect iridescent virus type 22."
    Cameron I.R.
    Virology 178:35-42(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Entry informationi

Entry nameiMCP_IRV22
AccessioniPrimary (citable) accession number: P22166
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 16, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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