P22166 (MCP_IRV22) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Major capsid protein
Short name=MCP

Alternative name(s):
P50

Gene names

Name:

MCP

Organism

Simulium iridescent virus (IIV-22) (Insect iridescent virus type 22)

Taxonomic identifier

10489 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Iridoviridae › Iridovirus › unclassified Iridovirus › Invertebrate iridescent virus 22

Virus host

Simulium [TaxID: 7191]

Protein attributes

Sequence length	472 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass By similarity.
Subunit structure	Homotrimer By similarity.
Subcellular location	Virion Potential.
Post-translational modification	The N-terminus is blocked.
Sequence similarities	Belongs to the NCLDV major capsid protein family.

Ontologies

Keywords
Cellular component	Virion
Developmental stage	Late protein
Molecular function	Capsid protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 472	472	Major capsid protein		PRO_0000222384

Sequences

	Sequence		Length	Mass (Da)
	P22166 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: B3D81F790AE9EFE9	FASTA	472	51,993
	10 20 30 40 50 60 MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV PLSRNTGNAA 70 80 90 100 110 120 FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL RWTKNLMHNL IREATITFND 130 140 150 160 170 180 LVAARFDNYH LDFWSAFTVP ASKRNGYDNM IGNVSSLINP VAPGGTLGSV GGINLNLPLP 190 200 210 220 230 240 FFFSRDTGVA LPTAALPYNE MQINFNFRDW HELLILTNSA LVPPASSYVS IVVGTHISAA 250 260 270 280 290 300 PVLGPVQVWA NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA 310 320 330 340 350 360 IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY ENTNRLGAMG 370 380 390 400 410 420 SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST NYGKLTNVFV VPAASSAAIS 430 440 450 460 470 AAGGTGGQAG SDYAQSYEFV IVAVNNNIVR IENSLVRNRR RWSREGPMVM VC

References

[1]	"Identification and characterization of the gene encoding the major structural protein of insect iridescent virus type 22." Cameron I.R. Virology 178:35-42(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M32799 Genomic DNA. Translation: AAA66585.1.
PIR	VCXFSI. B37075.
3D structure databases
ProteinModelPortal	P22166.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.70.9.10. 1 hit. 2.70.9.20. 1 hit.
InterPro	IPR016114. ASFV_p72. IPR016111. Hexon_subdom4. IPR016112. Virus_hexon. IPR007542. Virus_major_coat_C. [Graphical view]
Pfam	PF04451. Capsid_NCLDV. 1 hit. [Graphical view]
SUPFAM	SSF49749. Coat_hexon/vp54/p3_dsDNA-vir. 2 hits.
ProtoNet	Search...

Entry information

Entry name

MCP_IRV22

Accession

Primary (citable) accession number: P22166

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program