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P22166

- MCP_IRV22

UniProt

P22166 - MCP_IRV22

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Protein

Major capsid protein

Gene

MCP

Organism
Simulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass (By similarity).By similarity

GO - Molecular functioni

  1. structural molecule activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein
Short name:
MCP
Alternative name(s):
P50
Gene namesi
Name:MCP
OrganismiSimulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Taxonomic identifieri10489 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiSimulium [TaxID: 7191]

Subcellular locationi

Virion Curated

GO - Cellular componenti

  1. viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 472472Major capsid proteinPRO_0000222384Add
BLAST

Post-translational modificationi

The N-terminus is blocked.

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Homotrimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP22166.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NCLDV major capsid protein family.Curated

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.

Sequencei

Sequence statusi: Complete.

P22166-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV
60 70 80 90 100
PLSRNTGNAA FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL
110 120 130 140 150
RWTKNLMHNL IREATITFND LVAARFDNYH LDFWSAFTVP ASKRNGYDNM
160 170 180 190 200
IGNVSSLINP VAPGGTLGSV GGINLNLPLP FFFSRDTGVA LPTAALPYNE
210 220 230 240 250
MQINFNFRDW HELLILTNSA LVPPASSYVS IVVGTHISAA PVLGPVQVWA
260 270 280 290 300
NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA
310 320 330 340 350
IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY
360 370 380 390 400
ENTNRLGAMG SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST
410 420 430 440 450
NYGKLTNVFV VPAASSAAIS AAGGTGGQAG SDYAQSYEFV IVAVNNNIVR
460 470
IENSLVRNRR RWSREGPMVM VC
Length:472
Mass (Da):51,993
Last modified:August 1, 1991 - v1
Checksum:iB3D81F790AE9EFE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32799 Genomic DNA. Translation: AAA66585.1.
PIRiB37075. VCXFSI.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32799 Genomic DNA. Translation: AAA66585.1 .
PIRi B37075. VCXFSI.

3D structure databases

ProteinModelPortali P22166.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProi IPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view ]
Pfami PF04451. Capsid_NCLDV. 1 hit.
[Graphical view ]
SUPFAMi SSF49749. SSF49749. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of the gene encoding the major structural protein of insect iridescent virus type 22."
    Cameron I.R.
    Virology 178:35-42(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Entry informationi

Entry nameiMCP_IRV22
AccessioniPrimary (citable) accession number: P22166
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 1, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3