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P22166

- MCP_IRV22

UniProt

P22166 - MCP_IRV22

Protein

Major capsid protein

Gene

MCP

Organism
Simulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Aug 1991)
      Previous versions | rss
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    Functioni

    Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass By similarity.By similarity

    GO - Molecular functioni

    1. structural molecule activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Major capsid protein
    Short name:
    MCP
    Alternative name(s):
    P50
    Gene namesi
    Name:MCP
    OrganismiSimulium iridescent virus (IIV-22) (Insect iridescent virus type 22)
    Taxonomic identifieri10489 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
    Virus hostiSimulium [TaxID: 7191]

    Subcellular locationi

    Virion Curated

    GO - Cellular componenti

    1. viral capsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 472472Major capsid proteinPRO_0000222384Add
    BLAST

    Post-translational modificationi

    The N-terminus is blocked.

    Expressioni

    Keywords - Developmental stagei

    Late protein

    Interactioni

    Subunit structurei

    Homotrimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP22166.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NCLDV major capsid protein family.Curated

    Family and domain databases

    Gene3Di2.70.9.10. 1 hit.
    2.70.9.20. 1 hit.
    InterProiIPR016114. ASFV_p72.
    IPR016111. Hexon_subdom4.
    IPR007542. Virus_major_coat_C.
    IPR016112. VP_dsDNA_II.
    [Graphical view]
    PfamiPF04451. Capsid_NCLDV. 1 hit.
    [Graphical view]
    SUPFAMiSSF49749. SSF49749. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    P22166-1 [UniParc]FASTAAdd to Basket

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    MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV    50
    PLSRNTGNAA FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL 100
    RWTKNLMHNL IREATITFND LVAARFDNYH LDFWSAFTVP ASKRNGYDNM 150
    IGNVSSLINP VAPGGTLGSV GGINLNLPLP FFFSRDTGVA LPTAALPYNE 200
    MQINFNFRDW HELLILTNSA LVPPASSYVS IVVGTHISAA PVLGPVQVWA 250
    NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA 300
    IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY 350
    ENTNRLGAMG SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST 400
    NYGKLTNVFV VPAASSAAIS AAGGTGGQAG SDYAQSYEFV IVAVNNNIVR 450
    IENSLVRNRR RWSREGPMVM VC 472
    Length:472
    Mass (Da):51,993
    Last modified:August 1, 1991 - v1
    Checksum:iB3D81F790AE9EFE9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M32799 Genomic DNA. Translation: AAA66585.1.
    PIRiB37075. VCXFSI.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M32799 Genomic DNA. Translation: AAA66585.1 .
    PIRi B37075. VCXFSI.

    3D structure databases

    ProteinModelPortali P22166.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.70.9.10. 1 hit.
    2.70.9.20. 1 hit.
    InterProi IPR016114. ASFV_p72.
    IPR016111. Hexon_subdom4.
    IPR007542. Virus_major_coat_C.
    IPR016112. VP_dsDNA_II.
    [Graphical view ]
    Pfami PF04451. Capsid_NCLDV. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49749. SSF49749. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Identification and characterization of the gene encoding the major structural protein of insect iridescent virus type 22."
      Cameron I.R.
      Virology 178:35-42(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiMCP_IRV22
    AccessioniPrimary (citable) accession number: P22166
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1991
    Last sequence update: August 1, 1991
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3