P22047 (NCAP_PHV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoprotein

Alternative name(s):
Nucleocapsid protein
Short name=Protein N

Gene names

Name:

N

Organism

Prospect Hill virus (PHV)

Taxonomic identifier

11603 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Hantavirus

Virus host

Microtus pennsylvanicus (Meadow vole) [TaxID: 10058]

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Virion. Note: Internal protein of virus particle.
Sequence similarities	Belongs to the hantavirus nucleocapsid protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding Viral nucleoprotein
Molecular function	Ribonucleoprotein
Gene Ontology (GO)
Cellular_component	ribonucleoprotein complex Inferred from electronic annotation. Source: UniProtKB-KW viral nucleocapsid Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Nucleoprotein		PRO_0000222010
Experimental info
	Sequence conflict	7	1	I → T in AAA47086. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P22047 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: EBBD8161AD32A0CD	FASTA	433	49,005
	10 20 30 40 50 60 MSQLREIQEE ITRHEQQLVI ARQKLKEAER TVEVDPDDVN KSTLQSRRSA VSTLEDKLAE 70 80 90 100 110 120 FKRQLADVIS RQKMDEKPVD PTGIELDDHL KERSSLQYGN VLDVNSIDIE EPSGQTADWL 130 140 150 160 170 180 KIGSYIIEFA LPIILKALHM LSTRGRQTVK ENKGTRIRFK DDSSYEDVNG IRRPKHLYVS 190 200 210 220 230 240 MPTAQSTMKA EELTPGRFRT IVCGLFPAQI MARNIISPVM GVIGFAFFVK DWADKVKAFL 250 260 270 280 290 300 DQKCPFLKAE PRPGQPAGEA EFLSSIRAYL MNRQAVLDET HLPDIDALVE LAASGDPTLP 310 320 330 340 350 360 DSLENPHAAW VFACAPDRCP PTCIYIAGMA ELGAFFAILQ DMRNTIMASK TVGTAEEKLK 370 380 390 400 410 420 KKSAFYQSYL RRTQSMGIQL DQRIILMYMI EWGNEVVNHF HLGDDMDPEL RQLAQALIDQ 430 KVKEISNQEP LKI

References

[1]	"Nucleotide sequence analysis of the S genomic segment of Prospect Hill virus: comparison with the prototype Hantavirus." Parrington M.A., Kang C.Y. Virology 175:167-175(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: PHV-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M34011 Genomic RNA. Translation: AAA47086.1.
PIR	VHVUPH. A34681.
3D structure databases
ProteinModelPortal	P22047.
SMR	P22047. Positions 1-74.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002214. Hanta_nucleocap. [Graphical view]
Pfam	PF00846. Hanta_nucleocap. 1 hit. [Graphical view]
PIRSF	PIRSF003949. N_HantaV. 1 hit.
ProDom	PD001501. Hanta_nucleocap. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

NCAP_PHV

Accession

Primary (citable) accession number: P22047

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program