P22039 (Y191_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized PKHD-type hydroxylase sll0191
EC=1.14.11.-

Alternative name(s):
ORF60-3

Gene names

Ordered Locus Names:

sll0191

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 Fe2+ ion per subunit By similarity. Ascorbate By similarity.
Sequence similarities	Contains 1 Fe2OG dioxygenase domain.

Ontologies

Keywords
Ligand	Iron Metal-binding Vitamin C
Molecular function	Dioxygenase Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	L-ascorbic acid binding Inferred from electronic annotation. Source: UniProtKB-KW iron ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Uncharacterized PKHD-type hydroxylase sll0191		PRO_0000206689
Regions
	Domain	173 – 300	128	Fe2OG dioxygenase
Experimental info
	Sequence conflict	216	1	A → S in AAA27285. Ref.3
	Sequence conflict	245 – 303	59	LKNNT…RKKMN → A in AAA27285. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	P22039 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 0B91B8587842F037	FASTA	303	34,819
	10 20 30 40 50 60 MNRGAKVKTN GDNLALSTRA KKLLTKSIDT LETIIDNDQC SPQEKATIAL KILEMAGIFT 70 80 90 100 110 120 EFKHHSVDKL VAKAEEKIRR LQSQYPQINL SLSEPTLHQQ SESIFLPGTY GEIKNFLSPE 130 140 150 160 170 180 ENQKIITEAI DKKEEYIKSN TTTKANQYRQ SYVLFSQKIP ALSALIRERI KQKLPELLGQ 190 200 210 220 230 240 LNFSPFEVAE IELQLTAHND GCYYRIHNDA GSEKTASRQI TYVYYFYQEP KAFSGGELRL 250 260 270 280 290 300 YDTELKNNTI TTHPKFQTIT PINNSIIFFN SRCRHEVMSV VCPSREFAHS RFTVNGWIRK KMN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region from map positions 64% to 92% of the genome." Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N., Sugiura M., Tabata S. DNA Res. 2:153-166(1995) [PubMed: 8590279] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[3]	"Molecular cloning of the genes encoding two chaperone proteins of the cyanobacterium Synechocystis sp. PCC 6803." Chitnis P.R., Nelson N. J. Biol. Chem. 266:58-65(1991) [PubMed: 1670771] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA10239.1. M57517 Genomic DNA. Translation: AAA27285.1.
PIR	S76387.
RefSeq	NP_442169.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P22039.
ModBase	Search...
Protein-protein interaction databases
IntAct	P22039. 3 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	952622.
GenomeReviews	Gene locus sll0191 in contig BA000022_GR.
KEGG	syn:sll0191.
NMPDR	fig|1148.1.peg.2270.
PATRIC	23841958. VBISynSp132158_2521.
Phylogenomic databases
eggNOG	COG3751.
HOGENOM	HBG708523.
OMA	YVYYFYQ.
ProtClustDB	CLSK515824.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0191-MONOMER.
Family and domain databases
InterPro	IPR005123. Oxoglutarate/Fe-dep_oxygenase. IPR006620. Pro_4_hyd_alph. [Graphical view]
SMART	SM00702. P4Hc. 1 hit. [Graphical view]
PROSITE	PS51471. FE2OG_OXY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y191_SYNY3

Accession

Primary (citable) accession number: P22039
Secondary accession number(s): Q55706

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 74 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program