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Protein

Myb-like DNA-binding protein BAS1

Gene

BAS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Activates HIS4 transcription only in combination with PHO2/BAS2. BAS1 is also involved in the regulation of the purine biosynthesis pathway.1 Publication

Miscellaneous

Present with 861 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi138 – 161H-T-H motifPROSITE-ProRule annotationAdd BLAST24
DNA bindingi191 – 214H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-32061-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Myb-like DNA-binding protein BAS1
Gene namesi
Name:BAS1
Ordered Locus Names:YKR099W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XI

Organism-specific databases

EuPathDBiFungiDB:YKR099W.
SGDiS000001807. BAS1.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: SGD

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001970851 – 811Myb-like DNA-binding protein BAS1Add BLAST811

Proteomic databases

MaxQBiP22035.
PRIDEiP22035.

PTM databases

iPTMnetiP22035.

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

BioGridi34230. 257 interactors.
DIPiDIP-142N.
IntActiP22035. 8 interactors.
MINTiMINT-407810.
STRINGi4932.YKR099W.

Structurei

3D structure databases

ProteinModelPortaliP22035.
SMRiP22035.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 110Myb-likePROSITE-ProRule annotationAdd BLAST77
Domaini111 – 165HTH myb-type 1PROSITE-ProRule annotationAdd BLAST55
Domaini166 – 218HTH myb-type 2PROSITE-ProRule annotationAdd BLAST53

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00390000001038.
HOGENOMiHOG000001098.
InParanoidiP22035.
KOiK09423.
OMAiKISIHQH.
OrthoDBiEOG092C436P.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017877. Myb-like_dom.
IPR017930. Myb_dom.
IPR001005. SANT/Myb.
PfamiView protein in Pfam
PF00249. Myb_DNA-binding. 2 hits.
SMARTiView protein in SMART
SM00717. SANT. 3 hits.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS51294. HTH_MYB. 2 hits.
PS50090. MYB_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

P22035-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNISTKDIR KSKPKRGSGF DLLEVTESLG YQTHRKNGRN SWSKDDDNML
60 70 80 90 100
RSLVNESAKE LGYENGLEDV KTIQQSNHLS KCIAWDVLAT RFKHTVRTSK
110 120 130 140 150
DVRKRWTGSL DPNLKKGKWT QEEDEQLLKA YEEHGPHWLS ISMDIPGRTE
160 170 180 190 200
DQCAKRYIEV LGPGSKGRLR EWTLEEDLNL ISKVKAYGTK WRKISSEMEF
210 220 230 240 250
RPSLTCRNRW RKIITMVVRG QASEVITKAI KENKNIDMTD GKLRQHPIAD
260 270 280 290 300
SDIRSDSTPN KEEQLQLSQQ NNPSLIKQDI LNVKENESSK LPRLKDNDGP
310 320 330 340 350
ILNDSKPQAL PPLKEISAPP PIRMTQVGQT HTSGSIRSKV SLPIEGLSQM
360 370 380 390 400
NKQSPGGISD SPQTSLPPAF NPASLDEHMM NSNSISDSPK HAYSTVKTRE
410 420 430 440 450
PNSSSTQWKF TLKDGQGLSI SNGTIDSTKL VKELVDQAKK YSLKISIHQH
460 470 480 490 500
IHNHYVTSTD HPVSSNTGLS NIGNINGNPL LMDSFPHMGR QLGNGLPGLN
510 520 530 540 550
SNSDTFNPEY RTSLDNMDSD FLSRTPNYNA FSLEATSHNP ADNANELGSQ
560 570 580 590 600
SNRETNSPSV FYPQANTLIP TNSTATNNEI IQGNVSANSM SPNFNGTNGK
610 620 630 640 650
APSSTASYTT SGSEMPPDVG PNRIAHFNYL PPTIRPHLGS SDATRGADLN
660 670 680 690 700
KLLNPSPNSV RSNGSKTKKK EKRKSESSQH HSSSSVTTNK FNHIDQSEIS
710 720 730 740 750
RTTSRSDTPL RDEDGLDFWE TLRSLATTNP NPPVEKSAEN DGAKPQVVHQ
760 770 780 790 800
GIGSHTEDSS LGSHSGGYDF FNELLDKKAD TLHNEAKKTS EHDMTSGGST
810
DNGSVLPLNP S
Length:811
Mass (Da):89,604
Last modified:August 1, 1991 - v1
Checksum:iE874E72A3B7BDDE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M58057 Genomic DNA. Translation: AAB04030.1.
Z28324 Genomic DNA. Translation: CAA82179.1.
BK006944 Genomic DNA. Translation: DAA09250.1.
PIRiA40083.
RefSeqiNP_013025.3. NM_001179889.3.

Genome annotation databases

EnsemblFungiiYKR099W; YKR099W; YKR099W.
GeneIDi853974.
KEGGisce:YKR099W.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiBAS1_YEAST
AccessioniPrimary (citable) accession number: P22035
Secondary accession number(s): D6VXG0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: July 5, 2017
This is version 159 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XI
    Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names