P22025 (NCAP_UUKS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoprotein

Alternative name(s):
Nucleocapsid protein
Short name=Protein N

Gene names

Name:

N

Organism

Uukuniemi virus (strain S23) (Uuk) [Reference proteome]

Taxonomic identifier

487099 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Phlebovirus › Uukuniemi virus

Virus host

Homo sapiens (Human) [TaxID: 9606]
Ixodes ricinus (Common tick) [TaxID: 34613]

Protein attributes

Sequence length	254 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Virion Potential.
Sequence similarities	Belongs to the phlebovirus nucleocapsid protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding Viral nucleoprotein
Molecular function	Ribonucleoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	ribonucleoprotein complex Inferred from electronic annotation. Source: UniProtKB-KW viral nucleocapsid Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 254	254	Nucleoprotein		PRO_0000221998

Sequences

	Sequence		Length	Mass (Da)
	P22025 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: 922CBA7CDD7C6B12	FASTA	254	28,508
	10 20 30 40 50 60 MAMPENWVRF AIEISDAQWE EEEIREFINL FQYQGFDAAV VLSRIFELAK KADLSRDQML 70 80 90 100 110 120 RDIRALITLH LTRGNKLSSI EKRLSEEGKK EFALLKARYQ LVDKAKEAAD LTLSRIAIAN 130 140 150 160 170 180 AGLTCRILPQ VVAHTAVTRS RMESLSADYP VCMMHNAFAG LIDETLPEDS IKALVDAHRL 190 200 210 220 230 240 YLLEFSRTIN VKHRGMEAKE ILDANDSALQ AGLASSFLTP SQKRAYLLSF KLVDGNGKVN 250 KAVQQAATVL RSLI

References

[1]

"Uukuniemi virus S RNA segment: ambisense coding strategy, packaging of complementary strands into virions, and homology to members of the genus Phlebovirus." Simons J.F., Hellman U., Pettersson R.F. J. Virol. 64:247-255(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M33551 Genomic RNA. Translation: AAA47958.1.
PIR	VHVUUU. A33559.
RefSeq	NP_941980.1. NC_005221.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6457835.
Family and domain databases
InterPro	IPR009522. Capsid_Phlebovir/Tenuivir. IPR015971. Nucleocapsid_Phlebovirus. [Graphical view]
Pfam	PF05733. Tenui_N. 1 hit. [Graphical view]
PIRSF	PIRSF003953. N_PhelboV. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NCAP_UUKS

Accession

Primary (citable) accession number: P22025

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program