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P21992 (FLAB3_TREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Flagellar filament 31 kDa core protein
Alternative name(s):
Class B
Gene names
Name:flaB3
Ordered Locus Names:TP_0870
OrganismTreponema pallidum (strain Nichols) [Complete proteome] [HAMAP]
Taxonomic identifier243276 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Component of the core of the flagella.

Subunit structure

The flagellum consists of an outer layer composed of repeating units of flaA around a core that contains several antigenically related polypeptides.

Subcellular location

Periplasmic flagellum. Periplasm.

Sequence similarities

Belongs to the bacterial flagellin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 285285Flagellar filament 31 kDa core protein
PRO_0000182636

Experimental info

Sequence conflict251 – 2522QQ → HE in CAA45382. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P21992 [UniParc].

Last modified December 15, 1998. Version 3.
Checksum: CB75EBCFDE8B1244

FASTA28531,055
        10         20         30         40         50         60 
MIINHNMSAM FAQRQGGING LAIAKNIEKL SSGYRINRAG DDASGLAVSE KMRSQIRGLN 

        70         80         90        100        110        120 
QAGQNIQNGI SFIQATEGYL AETTEIVQRL RELAIQAANG IYSAEDRMQI QVEVSQLVDE 

       130        140        150        160        170        180 
VDRIASQAQF NGMNLLTGRF SRESALGPMQ LHVGANMDQN EKIFINTMTA SALGFFSDEG 

       190        200        210        220        230        240 
TDGSRSISIA TVDGANKVIG TLDSALKEIN KQRADLGAYQ NRFETAYQGI AIAAENLQAA 

       250        260        270        280 
ESRIRDADLA QQMVDYTKNQ ILEQSTMAML AQANTQPQAV LRLMQ

« Hide

References

« Hide 'large scale' references
[1]"Cloning, sequencing, and expression of two class B endoflagellar genes of Treponema pallidum subsp. pallidum encoding the 34.5- and 31.0-kilodalton proteins."
Champion C.I., Miller J.N., Lovett M.A., Blanco D.R.
Infect. Immun. 58:1697-1704(1990) [PubMed: 2187805] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Nichols.
[2]"Complete genome sequence of Treponema pallidum, the syphilis spirochete."
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. expand/collapse author list , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C.
Science 281:375-388(1998) [PubMed: 9665876] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols.
[3]"Antigenic relatedness and N-terminal sequence homology define two classes of periplasmic flagellar proteins of Treponema pallidum subsp. pallidum and Treponema phagedenis."
Norris S.J., Charon N.W., Cook R.G., Fuentes M.D., Limberger R.J.
J. Bacteriol. 170:4072-4082(1988) [PubMed: 3045083] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-30.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X63965 Genomic DNA. Translation: CAA45382.1.
AE000520 Genomic DNA. Translation: AAC65835.1.
PIRA41489.
RefSeqNP_219305.1. NC_000919.1.

3D structure databases

ProteinModelPortalP21992.
SMRP21992. Positions 246-284.
ModBaseSearch...

Protein-protein interaction databases

IntActP21992. 102 interactions.
MINTMINT-6480802.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2611107.
GenomeReviewsGene locus TP_0870 in contig AE000520_GR.
KEGGtpa:TP0870.
NMPDRfig|243276.1.peg.864.
PATRIC20531851. VBITrePal57110_0923.
TIGRTP_0870.

Phylogenomic databases

HOGENOMHBG758847.
OMAGHQNGED.
ProtClustDBCLSK2749656.

Enzyme and pathway databases

BioCycTPAL243276:TP_0870-MONOMER.

Family and domain databases

InterProIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
[Graphical view]
KOK02406.
PfamPF00700. Flagellin_C. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSPR00207. FLAGELLIN.
ProtoNetSearch...

Entry information

Entry nameFLAB3_TREPA
AccessionPrimary (citable) accession number: P21992
Secondary accession number(s): O83840
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: December 15, 1998
Last modified: January 25, 2012
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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