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P21908 (GLK_ZYMMO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:ZMO0369
OrganismZymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) [Complete proteome] [HAMAP]
Taxonomic identifier264203 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 324324Glucokinase HAMAP-Rule MF_00524
PRO_0000215147

Regions

Nucleotide binding6 – 116ATP Potential

Experimental info

Sequence conflict2581A → R Ref.1
Sequence conflict2581A → R Ref.2
Sequence conflict313 – 32412AAAYA…YSEVE → QLPMPTNILKLNNIF Ref.1
Sequence conflict313 – 32412AAAYA…YSEVE → QLPMPTNILKLNNIF Ref.2

Sequences

Sequence LengthMass (Da)Tools
P21908 [UniParc].

Last modified February 15, 2005. Version 2.
Checksum: BAAC13AAB6DB8716

FASTA32434,897
        10         20         30         40         50         60 
MEIVAIDIGG THARFSIAEV SNGRVLSLGE ETTFKTAEHA SLQLAWERFG EKLGRPLPRA 

        70         80         90        100        110        120 
AAIAWAGPVH GEVLKLTNNP WVLRPATLNE KLDIDTHVLI NDFGAVAHAV AHMDSSYLDH 

       130        140        150        160        170        180 
ICGPDEALPS DGVITILGPG TGLGVAHLLR TEGRYFVIET EGGHIDFAPL DRLEDKILAR 

       190        200        210        220        230        240 
LRERFRRVSI ERIISGPGLG NIYEALAAIE GVPFSLLDDI KLWQMALEGK DNLAEAALDR 

       250        260        270        280        290        300 
FCLSLGAIAG DLALAQGATS VVIGGGVGLR IASHLPESGF RQRFVSKGRF ERVMSKIPVK 

       310        320 
LITYPQPGLL GAAAAYANKY SEVE 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and genetic organization of a Zymomonas mobilis gene cluster that encodes several enzymes of glucose metabolism."
Barnell W.O., Yi K.C., Conway T.
J. Bacteriol. 172:7227-7240(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 31821 / ZM4 / CP4.
[2]Ahn J.Y., Kang H.S.
Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 31821 / ZM4 / CP4.
[3]"The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4."
Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y. expand/collapse author list , Kang H.L., Lee S.Y., Lee K.J., Kang H.S.
Nat. Biotechnol. 23:63-68(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31821 / ZM4 / CP4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M60615 Genomic DNA. Translation: AAA27694.1.
AF313764 Genomic DNA. Translation: AAG29867.1.
AE008692 Genomic DNA. Translation: AAV88993.1.
PIRD37855.
RefSeqYP_162104.1. NC_006526.2.

3D structure databases

ProteinModelPortalP21908.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264203.ZMO0369.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV88993; AAV88993; ZMO0369.
GeneID3188599.
KEGGzmo:ZMO0369.
PATRIC32566072. VBIZymMob102260_0350.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_ZYMMO
AccessionPrimary (citable) accession number: P21908
Secondary accession number(s): Q5NQL1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: February 15, 2005
Last modified: June 11, 2014
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families