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Protein

Glucokinase

Gene

glk

Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 116ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:ZMO0369
OrganismiZymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Taxonomic identifieri264203 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas
ProteomesiUP000001173: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 324324GlucokinasePRO_0000215147Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264203.ZMO0369.

Structurei

3D structure databases

ProteinModelPortaliP21908.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

P21908-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIVAIDIGG THARFSIAEV SNGRVLSLGE ETTFKTAEHA SLQLAWERFG
60 70 80 90 100
EKLGRPLPRA AAIAWAGPVH GEVLKLTNNP WVLRPATLNE KLDIDTHVLI
110 120 130 140 150
NDFGAVAHAV AHMDSSYLDH ICGPDEALPS DGVITILGPG TGLGVAHLLR
160 170 180 190 200
TEGRYFVIET EGGHIDFAPL DRLEDKILAR LRERFRRVSI ERIISGPGLG
210 220 230 240 250
NIYEALAAIE GVPFSLLDDI KLWQMALEGK DNLAEAALDR FCLSLGAIAG
260 270 280 290 300
DLALAQGATS VVIGGGVGLR IASHLPESGF RQRFVSKGRF ERVMSKIPVK
310 320
LITYPQPGLL GAAAAYANKY SEVE
Length:324
Mass (Da):34,897
Last modified:February 15, 2005 - v2
Checksum:iBAAC13AAB6DB8716
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti258 – 2581A → R (PubMed:2254282).Curated
Sequence conflicti258 – 2581A → R (Ref. 2) Curated
Sequence conflicti313 – 32412AAAYA…YSEVE → QLPMPTNILKLNNIF (PubMed:2254282).CuratedAdd
BLAST
Sequence conflicti313 – 32412AAAYA…YSEVE → QLPMPTNILKLNNIF (Ref. 2) CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60615 Genomic DNA. Translation: AAA27694.1.
AF313764 Genomic DNA. Translation: AAG29867.1.
AE008692 Genomic DNA. Translation: AAV88993.1.
PIRiD37855.
RefSeqiYP_162104.1. NC_006526.2.

Genome annotation databases

EnsemblBacteriaiAAV88993; AAV88993; ZMO0369.
GeneIDi3188599.
KEGGizmo:ZMO0369.
PATRICi32566072. VBIZymMob102260_0350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60615 Genomic DNA. Translation: AAA27694.1.
AF313764 Genomic DNA. Translation: AAG29867.1.
AE008692 Genomic DNA. Translation: AAV88993.1.
PIRiD37855.
RefSeqiYP_162104.1. NC_006526.2.

3D structure databases

ProteinModelPortaliP21908.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264203.ZMO0369.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV88993; AAV88993; ZMO0369.
GeneIDi3188599.
KEGGizmo:ZMO0369.
PATRICi32566072. VBIZymMob102260_0350.

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiGHADFAP.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and genetic organization of a Zymomonas mobilis gene cluster that encodes several enzymes of glucose metabolism."
    Barnell W.O., Yi K.C., Conway T.
    J. Bacteriol. 172:7227-7240(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 31821 / ZM4 / CP4.
  2. Ahn J.Y., Kang H.S.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 31821 / ZM4 / CP4.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31821 / ZM4 / CP4.

Entry informationi

Entry nameiGLK_ZYMMO
AccessioniPrimary (citable) accession number: P21908
Secondary accession number(s): Q5NQL1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: February 15, 2005
Last modified: January 7, 2015
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.