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Protein

Single-stranded-DNA-specific exonuclease RecJ

Gene

recJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available.1 Publication

GO - Molecular functioni

GO - Biological processi

  • DNA recombination Source: EcoCyc
  • DNA repair Source: EcoCyc
  • response to X-ray Source: EcoCyc

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciEcoCyc:EG10830-MONOMER
MetaCyc:EG10830-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded-DNA-specific exonuclease RecJ (EC:3.1.-.-)
Gene namesi
Name:recJ
Ordered Locus Names:b2892, JW2860
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10830 recJ

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000972281 – 577Single-stranded-DNA-specific exonuclease RecJAdd BLAST577

Proteomic databases

PaxDbiP21893
PRIDEiP21893

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
topBP142944EBI-556893,EBI-552080

Protein-protein interaction databases

BioGridi4262338, 178 interactors
DIPiDIP-10654N
IntActiP21893, 26 interactors
STRINGi316385.ECDH10B_3066

Structurei

3D structure databases

ProteinModelPortaliP21893
SMRiP21893
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecJ family.Curated

Phylogenomic databases

eggNOGiENOG4105C2R Bacteria
COG0608 LUCA
HOGENOMiHOG000018414
InParanoidiP21893
KOiK07462
OMAiFIICDHH
PhylomeDBiP21893

Family and domain databases

InterProiView protein in InterPro
IPR001667 DDH_dom
IPR038763 DHH_sf
IPR003156 DHHA1_dom
IPR004610 RecJ
PfamiView protein in Pfam
PF01368 DHH, 1 hit
PF02272 DHHA1, 1 hit
SUPFAMiSSF64182 SSF64182, 1 hit
TIGRFAMsiTIGR00644 recJ, 1 hit

Sequencei

Sequence statusi: Complete.

P21893-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQQIQLRRR EVDETADLPA ELPPLLRRLY ASRGVRSAQE LERSVKGMLP
60 70 80 90 100
WQQLSGVEKA VEILYNAFRE GTRIIVVGDF DADGATSTAL SVLAMRSLGC
110 120 130 140 150
SNIDYLVPNR FEDGYGLSPE VVDQAHARGA QLIVTVDNGI SSHAGVEHAR
160 170 180 190 200
SLGIPVIVTD HHLPGDTLPA AEAIINPNLR DCNFPSKSLA GVGVAFYLML
210 220 230 240 250
ALRTFLRDQG WFDERNIAIP NLAELLDLVA LGTVADVVPL DANNRILTWQ
260 270 280 290 300
GMSRIRAGKC RPGIKALLEV ANRDAQKLAA SDLGFALGPR LNAAGRLDDM
310 320 330 340 350
SVGVALLLCD NIGEARVLAN ELDALNQTRK EIEQGMQIEA LTLCEKLERS
360 370 380 390 400
RDTLPGGLAM YHPEWHQGVV GILASRIKER FHRPVIAFAP AGDGTLKGSG
410 420 430 440 450
RSIQGLHMRD ALERLDTLYP GMMLKFGGHA MAAGLSLEED KFKLFQQRFG
460 470 480 490 500
ELVTEWLDPS LLQGEVVSDG PLSPAEMTME VAQLLRDAGP WGQMFPEPLF
510 520 530 540 550
DGHFRLLQQR LVGERHLKVM VEPVGGGPLL DGIAFNVDTA LWPDNGVREV
560 570
QLAYKLDINE FRGNRSLQII IDNIWPI
Length:577
Mass (Da):63,389
Last modified:November 1, 1997 - v2
Checksum:iCF7724B36D7701DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti6Q → H in AAA62789 (PubMed:1987126).Curated1
Sequence conflicti20A → AA in AAA62789 (PubMed:1987126).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M54884 Genomic DNA Translation: AAA62789.1
U28375 Genomic DNA Translation: AAA83073.1
U00096 Genomic DNA Translation: AAC75930.1
AP009048 Genomic DNA Translation: BAE76957.1
PIRiD65073
RefSeqiNP_417368.1, NC_000913.3
WP_000813200.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75930; AAC75930; b2892
BAE76957; BAE76957; BAE76957
GeneIDi947367
KEGGiecj:JW2860
eco:b2892
PATRICifig|1411691.4.peg.3841

Similar proteinsi

Entry informationi

Entry nameiRECJ_ECOLI
AccessioniPrimary (citable) accession number: P21893
Secondary accession number(s): Q2M9U9, Q46823
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 135 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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