Reviewed, UniProtKB/Swiss-Prot P21824 (CHER_ENTAE)

Names and origin

Protein names

Recommended name:
    Chemotaxis protein methyltransferase
    EC=2.1.1.80

Gene names

Name:

cheR

Organism

Enterobacter aerogenes (Aerobacter aerogenes)

Taxonomic identifier

548 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length	100 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
Catalytic activity	S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.
Sequence similarities	Contains 1 cheR-type methyltransferase domain.

Ontologies

Keywords
Biological process	Chemotaxis
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Gene Ontology (GO)
Biological process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein-glutamate O-methyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›100	›100	Chemotaxis protein methyltransferase		PRO_0000176034
Regions
	Domain	18 – ›100	›83	CheR-type methyltransferase
Sites
	Binding site	95	1	S-adenosyl-L-methionine By similarity
	Binding site	97	1	S-adenosyl-L-methionine By similarity
Experimental info
	Non-terminal residue	100	1

Sequences

	Sequence		Length	Mass (Da)
	P21824-1 [UniParc]. Last modified May 1, 1991. Version 1. Checksum: C352DD9CDB959F68	FASTA	100	11,438
	10 20 30 40 50 60 MKQDDINAAR ESGSAVAQMA QRLPLSDAHF RRISQLIYQR AGIVLAPHKR EMVYNRLVRR 70 80 90 100 LRLLGIHDFG DYLALLESDP HSAEWQAFIN ALTTNLTAFF

References

[1]	"Evolution of chemotactic-signal transducers in enteric bacteria." Dahl M.K., Boos W., Manson M.D. J. Bacteriol. 171:2361-2371(1989) [PubMed: 2496104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 13048 / DSM 30053 / IFO 13534 / JCM 1235 / NCTC 10006.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M26411 Genomic DNA. Translation: AAA24799.1.
PIR	E32302.
3D structure databases
HSSP	HSSP built from PDB template 1BC5 based on UniProtKB P07801.
SMR	P21824. Positions 14-100.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.1.1.80. 759.
Family and domain databases
InterPro	IPR000780. CheR_MeTrfase. [Graphical view]
Pfam	PF03705. CheR_N. 1 hit. [Graphical view]
PRINTS	PR00996. CHERMTFRASE.
PROSITE	PS50123. CHER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CHER_ENTAE

Accession

Primary (citable) accession number: P21824

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1991
Last sequence update:	May 1, 1991
Last modified:	January 20, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)