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P21701

- NCAP_TOSV

UniProt

P21701 - NCAP_TOSV

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Protein

Nucleoprotein

Gene

N

Organism
Toscana virus (Tos)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiToscana virus (Tos)
Taxonomic identifieri11590 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaePhlebovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Phlebotomus perniciosus [TaxID: 13204]

Subcellular locationi

Virion
Note: Internal protein of virus particle.

GO - Cellular componenti

  1. helical viral capsid Source: UniProtKB-KW
  2. ribonucleoprotein complex Source: UniProtKB-KW
  3. viral nucleocapsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 253253NucleoproteinPRO_0000221997Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-60331N.

Structurei

Secondary structure

1
253
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 116Combined sources
Helixi12 – 154Combined sources
Helixi20 – 3011Combined sources
Helixi37 – 5014Combined sources
Helixi55 – 6915Combined sources
Helixi73 – 764Combined sources
Helixi77 – 793Combined sources
Helixi82 – 9514Combined sources
Beta strandi99 – 1013Combined sources
Beta strandi104 – 1063Combined sources
Helixi109 – 1157Combined sources
Helixi117 – 12711Combined sources
Helixi128 – 1303Combined sources
Beta strandi131 – 1333Combined sources
Helixi135 – 1417Combined sources
Beta strandi142 – 1443Combined sources
Helixi148 – 1503Combined sources
Helixi153 – 1586Combined sources
Helixi164 – 1663Combined sources
Helixi167 – 18620Combined sources
Helixi188 – 1925Combined sources
Helixi195 – 21016Combined sources
Beta strandi213 – 2153Combined sources
Helixi217 – 22610Combined sources
Helixi238 – 25114Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4CSFX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-253[»]
4CSGX-ray3.32A/B/C/D/E/F/G/H/I/J/K/L1-253[»]
4H5LX-ray2.75A/B/C/D/E/F1-253[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view]
PfamiPF05733. Tenui_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003953. N_PhelboV. 1 hit.

Sequencei

Sequence statusi: Complete.

P21701-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDENYRDIA LAFLDESADS GTINAWVNEF AYQGFDPKRI VQLVKERGTA
60 70 80 90 100
KGRDWKKDVK MMIVLNLVRG NKPEAMMKKM SEKGASIVAN LISVYQLKEG
110 120 130 140 150
NPGRDTITLS RVSAAFVPWT VQALRVLSES LPVSGTTMDA IAGVTYPRAM
160 170 180 190 200
MHPSFAGIID LDLPNGAGAT IADAHGLFMI EFSKTINPSL RTKQANEVAA
210 220 230 240 250
TFEKPNMAAM SGRFFTREDK KKLLIAVGII DEDLVLASAV VRSAEKYRAK

VGK
Length:253
Mass (Da):27,704
Last modified:May 1, 1991 - v1
Checksum:i33ECBA8444A612D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1.
PIRiB38552. VHVUTV.
RefSeqiYP_089668.1. NC_006318.1.

Genome annotation databases

GeneIDi3077270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1 .
PIRi B38552. VHVUTV.
RefSeqi YP_089668.1. NC_006318.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4CSF X-ray 2.60 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X 1-253 [» ]
4CSG X-ray 3.32 A/B/C/D/E/F/G/H/I/J/K/L 1-253 [» ]
4H5L X-ray 2.75 A/B/C/D/E/F 1-253 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60331N.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3077270.

Family and domain databases

InterProi IPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view ]
Pfami PF05733. Tenui_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF003953. N_PhelboV. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses."
    Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L.
    Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNCAP_TOSV
AccessioniPrimary (citable) accession number: P21701
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: November 26, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3