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P21701

- NCAP_TOSV

UniProt

P21701 - NCAP_TOSV

Protein

Nucleoprotein

Gene

N

Organism
Toscana virus (Tos)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (01 May 1991)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ribonucleoprotein

    Keywords - Ligandi

    RNA-binding, Viral nucleoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleoprotein
    Alternative name(s):
    Nucleocapsid protein
    Short name:
    Protein N
    Gene namesi
    Name:N
    OrganismiToscana virus (Tos)
    Taxonomic identifieri11590 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaePhlebovirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    Phlebotomus perniciosus [TaxID: 13204]

    Subcellular locationi

    Virion
    Note: Internal protein of virus particle.

    GO - Cellular componenti

    1. helical viral capsid Source: UniProtKB-KW
    2. ribonucleoprotein complex Source: UniProtKB-KW
    3. viral nucleocapsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Helical capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 253253NucleoproteinPRO_0000221997Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-60331N.

    Structurei

    Secondary structure

    1
    253
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi6 – 116
    Helixi12 – 154
    Helixi20 – 3011
    Helixi37 – 5014
    Helixi55 – 6915
    Helixi73 – 764
    Helixi77 – 793
    Helixi82 – 9514
    Beta strandi99 – 1013
    Beta strandi104 – 1063
    Helixi109 – 1157
    Helixi117 – 12711
    Helixi128 – 1303
    Beta strandi131 – 1333
    Helixi135 – 1417
    Beta strandi142 – 1443
    Helixi148 – 1503
    Helixi153 – 1586
    Helixi164 – 1663
    Helixi167 – 18620
    Helixi188 – 1925
    Helixi195 – 21016
    Beta strandi213 – 2153
    Helixi217 – 22610
    Helixi238 – 25114

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4CSFX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-253[»]
    4CSGX-ray3.32A/B/C/D/E/F/G/H/I/J/K/L1-253[»]
    4H5LX-ray2.75A/B/C/D/E/F1-253[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR009522. Capsid_Phlebovir/Tenuivir.
    IPR015971. Nucleocapsid_Phlebovirus.
    [Graphical view]
    PfamiPF05733. Tenui_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003953. N_PhelboV. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P21701-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDENYRDIA LAFLDESADS GTINAWVNEF AYQGFDPKRI VQLVKERGTA    50
    KGRDWKKDVK MMIVLNLVRG NKPEAMMKKM SEKGASIVAN LISVYQLKEG 100
    NPGRDTITLS RVSAAFVPWT VQALRVLSES LPVSGTTMDA IAGVTYPRAM 150
    MHPSFAGIID LDLPNGAGAT IADAHGLFMI EFSKTINPSL RTKQANEVAA 200
    TFEKPNMAAM SGRFFTREDK KKLLIAVGII DEDLVLASAV VRSAEKYRAK 250
    VGK 253
    Length:253
    Mass (Da):27,704
    Last modified:May 1, 1991 - v1
    Checksum:i33ECBA8444A612D1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X53794 Genomic RNA. Translation: CAA37803.1.
    PIRiB38552. VHVUTV.
    RefSeqiYP_089668.1. NC_006318.1.

    Genome annotation databases

    GeneIDi3077270.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X53794 Genomic RNA. Translation: CAA37803.1 .
    PIRi B38552. VHVUTV.
    RefSeqi YP_089668.1. NC_006318.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4CSF X-ray 2.60 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X 1-253 [» ]
    4CSG X-ray 3.32 A/B/C/D/E/F/G/H/I/J/K/L 1-253 [» ]
    4H5L X-ray 2.75 A/B/C/D/E/F 1-253 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-60331N.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3077270.

    Family and domain databases

    InterProi IPR009522. Capsid_Phlebovir/Tenuivir.
    IPR015971. Nucleocapsid_Phlebovirus.
    [Graphical view ]
    Pfami PF05733. Tenui_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003953. N_PhelboV. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses."
      Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L.
      Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNCAP_TOSV
    AccessioniPrimary (citable) accession number: P21701
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1991
    Last sequence update: May 1, 1991
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3