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Protein

Nucleoprotein

Gene

N

Organism
Toscana virus (Tos)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiToscana virus (Tos)
Taxonomic identifieri11590 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA negative-strand virusesBunyaviridaePhlebovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Phlebotomus perniciosus [TaxID: 13204]

Subcellular locationi

  • Virion

  • Note: Internal protein of virus particle.

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002219971 – 253NucleoproteinAdd BLAST253

Interactioni

Protein-protein interaction databases

DIPiDIP-60331N.

Structurei

Secondary structure

1253
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 11Combined sources6
Helixi12 – 15Combined sources4
Helixi20 – 30Combined sources11
Helixi37 – 50Combined sources14
Helixi55 – 69Combined sources15
Helixi73 – 76Combined sources4
Helixi77 – 79Combined sources3
Helixi82 – 95Combined sources14
Beta strandi99 – 101Combined sources3
Beta strandi104 – 106Combined sources3
Helixi109 – 115Combined sources7
Helixi117 – 127Combined sources11
Helixi128 – 130Combined sources3
Beta strandi131 – 133Combined sources3
Helixi135 – 141Combined sources7
Beta strandi142 – 144Combined sources3
Helixi148 – 150Combined sources3
Helixi153 – 158Combined sources6
Helixi164 – 166Combined sources3
Helixi167 – 186Combined sources20
Helixi188 – 192Combined sources5
Helixi195 – 210Combined sources16
Beta strandi213 – 215Combined sources3
Helixi217 – 226Combined sources10
Helixi238 – 251Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4CSFX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-253[»]
4CSGX-ray3.32A/B/C/D/E/F/G/H/I/J/K/L1-253[»]
4H5LX-ray2.75A/B/C/D/E/F1-253[»]
5FVAX-ray3.70A/B/C/D/E/F2-253[»]
SMRiP21701.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view]
PfamiPF05733. Tenui_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003953. N_PhelboV. 1 hit.

Sequencei

Sequence statusi: Complete.

P21701-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDENYRDIA LAFLDESADS GTINAWVNEF AYQGFDPKRI VQLVKERGTA
60 70 80 90 100
KGRDWKKDVK MMIVLNLVRG NKPEAMMKKM SEKGASIVAN LISVYQLKEG
110 120 130 140 150
NPGRDTITLS RVSAAFVPWT VQALRVLSES LPVSGTTMDA IAGVTYPRAM
160 170 180 190 200
MHPSFAGIID LDLPNGAGAT IADAHGLFMI EFSKTINPSL RTKQANEVAA
210 220 230 240 250
TFEKPNMAAM SGRFFTREDK KKLLIAVGII DEDLVLASAV VRSAEKYRAK

VGK
Length:253
Mass (Da):27,704
Last modified:May 1, 1991 - v1
Checksum:i33ECBA8444A612D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1.
PIRiB38552. VHVUTV.
RefSeqiYP_089668.1. NC_006318.1.

Genome annotation databases

GeneIDi3077270.
KEGGivg:3077270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1.
PIRiB38552. VHVUTV.
RefSeqiYP_089668.1. NC_006318.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4CSFX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-253[»]
4CSGX-ray3.32A/B/C/D/E/F/G/H/I/J/K/L1-253[»]
4H5LX-ray2.75A/B/C/D/E/F1-253[»]
5FVAX-ray3.70A/B/C/D/E/F2-253[»]
SMRiP21701.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60331N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3077270.
KEGGivg:3077270.

Family and domain databases

InterProiIPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view]
PfamiPF05733. Tenui_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003953. N_PhelboV. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNCAP_TOSV
AccessioniPrimary (citable) accession number: P21701
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: November 30, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.