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P21701

- NCAP_TOSV

UniProt

P21701 - NCAP_TOSV

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Protein

Nucleoprotein

Gene

N

Organism
Toscana virus (Tos)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding, Viral nucleoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name:
Protein N
Gene namesi
Name:N
OrganismiToscana virus (Tos)
Taxonomic identifieri11590 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaePhlebovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Phlebotomus perniciosus [TaxID: 13204]

Subcellular locationi

Virion
Note: Internal protein of virus particle.

GO - Cellular componenti

  1. helical viral capsid Source: UniProtKB-KW
  2. ribonucleoprotein complex Source: UniProtKB-KW
  3. viral nucleocapsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 253253NucleoproteinPRO_0000221997Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-60331N.

Structurei

Secondary structure

1
253
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 116
Helixi12 – 154
Helixi20 – 3011
Helixi37 – 5014
Helixi55 – 6915
Helixi73 – 764
Helixi77 – 793
Helixi82 – 9514
Beta strandi99 – 1013
Beta strandi104 – 1063
Helixi109 – 1157
Helixi117 – 12711
Helixi128 – 1303
Beta strandi131 – 1333
Helixi135 – 1417
Beta strandi142 – 1443
Helixi148 – 1503
Helixi153 – 1586
Helixi164 – 1663
Helixi167 – 18620
Helixi188 – 1925
Helixi195 – 21016
Beta strandi213 – 2153
Helixi217 – 22610
Helixi238 – 25114

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4CSFX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X1-253[»]
4CSGX-ray3.32A/B/C/D/E/F/G/H/I/J/K/L1-253[»]
4H5LX-ray2.75A/B/C/D/E/F1-253[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view]
PfamiPF05733. Tenui_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003953. N_PhelboV. 1 hit.

Sequencei

Sequence statusi: Complete.

P21701-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDENYRDIA LAFLDESADS GTINAWVNEF AYQGFDPKRI VQLVKERGTA
60 70 80 90 100
KGRDWKKDVK MMIVLNLVRG NKPEAMMKKM SEKGASIVAN LISVYQLKEG
110 120 130 140 150
NPGRDTITLS RVSAAFVPWT VQALRVLSES LPVSGTTMDA IAGVTYPRAM
160 170 180 190 200
MHPSFAGIID LDLPNGAGAT IADAHGLFMI EFSKTINPSL RTKQANEVAA
210 220 230 240 250
TFEKPNMAAM SGRFFTREDK KKLLIAVGII DEDLVLASAV VRSAEKYRAK

VGK
Length:253
Mass (Da):27,704
Last modified:May 1, 1991 - v1
Checksum:i33ECBA8444A612D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1.
PIRiB38552. VHVUTV.
RefSeqiYP_089668.1. NC_006318.1.

Genome annotation databases

GeneIDi3077270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X53794 Genomic RNA. Translation: CAA37803.1 .
PIRi B38552. VHVUTV.
RefSeqi YP_089668.1. NC_006318.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4CSF X-ray 2.60 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X 1-253 [» ]
4CSG X-ray 3.32 A/B/C/D/E/F/G/H/I/J/K/L 1-253 [» ]
4H5L X-ray 2.75 A/B/C/D/E/F 1-253 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60331N.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3077270.

Family and domain databases

InterProi IPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view ]
Pfami PF05733. Tenui_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF003953. N_PhelboV. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses."
    Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L.
    Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNCAP_TOSV
AccessioniPrimary (citable) accession number: P21701
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: October 1, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3