P21700 (NCAP_RVFVZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoprotein

Alternative name(s):
Nucleocapsid protein
Short name=Protein N

Gene names

Name:

N

Organism

Rift valley fever virus (strain ZH-548 M12) (RVFV) [Reference proteome]

Taxonomic identifier

11589 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Phlebovirus › Rift valley fever virus

Virus host

Aedes [TaxID: 7158]
Bos taurus (Bovine) [TaxID: 9913]
Bos taurus x Bison bison (beefalo) [TaxID: 297284]
Camelus bactrianus (Bactrian camel) [TaxID: 9837]
Capra hircus (Goat) [TaxID: 9925]
Homo sapiens (Human) [TaxID: 9606]
Ovis aries (Sheep) [TaxID: 9940]
Phlebotomus papatasi (Sandfly) [TaxID: 29031]

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Virion. Note: Internal protein of virus particle.
Sequence similarities	Belongs to the phlebovirus nucleocapsid protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding Viral nucleoprotein
Molecular function	Ribonucleoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	ribonucleoprotein complex Inferred from electronic annotation. Source: UniProtKB-KW viral nucleocapsid Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 245

245

Nucleoprotein

PRO_0000221995

Secondary structure

1

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245

Helix Strand Turn

Details...

Helix

4 – 13

10

Helix

18 – 28

11

Helix

35 – 46

12

Helix

47 – 49

3

Helix

50 – 63

14

Helix

68 – 71

4

Helix

72 – 74

3

Helix

77 – 90

14

Beta strand

94 – 96

3

Helix

104 – 110

7

Helix

112 – 122

11

Helix

123 – 125

3

Beta strand

126 – 128

3

Helix

130 – 136

7

Helix

142 – 144

3

Helix

147 – 152

6

Helix

159 – 180

22

Helix

182 – 184

3

Helix

189 – 204

16

Beta strand

207 – 209

3

Helix

211 – 220

10

Helix

232 – 243

12

Sequences

	Sequence		Length	Mass (Da)
	P21700 [UniParc]. Last modified May 1, 1991. Version 1. Checksum: 8B6190549F4A6FF5	FASTA	245	27,431
	10 20 30 40 50 60 MDNYQELRVQ FAAQAVDRNE IEQWVREFAY QGFDARRVIE LLKQYGGADW EKDAKKMIVL 70 80 90 100 110 120 ALTRGNKPRR MMMKMSKEGK ATVEALINKY KLKEGNPSRD ELTLSRVAAA LAGWTCQALV 130 140 150 160 170 180 VLSEWLPVTG TTMDGLSPAY PRHMMHPSFA GMVDPSLPGD YLRAILDAHS LYLLQFSRVI 190 200 210 220 230 240 NPNLRGRTKE EVAATFTQPM NAAVNSNFIS HEKRREFLKA FGLVDSNGKP SAAVMAAAQA YKTAA

References

[1]

"Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses." Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L. Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X53771 Genomic RNA. Translation: CAA37789.1.

PIR

VHVURV. D38552.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3OUO	X-ray	2.30	A/B/C	1-245	[»]
3OV9	X-ray	1.60	A/B/C	1-245	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR009522. Capsid_Phlebovir/Tenuivir.
IPR015971. Nucleocapsid_Phlebovirus.
[Graphical view]

Pfam

PF05733. Tenui_N. 1 hit.
[Graphical view]

PIRSF

PIRSF003953. N_PhelboV. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

P21700.

Entry information

Entry name

NCAP_RVFVZ

Accession

Primary (citable) accession number: P21700

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1991
Last sequence update:	May 1, 1991
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program