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P21698 (NSS_RVFVZ) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Inhibits host general transcription by inhibiting host basal transcription factor TFIIH. Ref.2

Sequence similarities

Belongs to the phlebovirus NS-S protein family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Non-structural protein NS-S
PRO_0000221979

Sequences

Sequence LengthMass (Da)Tools
P21698 [UniParc].

Last modified May 1, 1991. Version 1.
Checksum: EF2608D29CEB6C84

FASTA26529,903
        10         20         30         40         50         60 
MDYFPVISVD LQSGRRVVSV EYFRGDGPPR IPYSMVGPCC VFLMHHRPSH EVRLRFSDFY 

        70         80         90        100        110        120 
NVGEFPYRVG LGDFASNVAP PPAKPFQRLI DLIGHMTLSD FTRFPNLKEA ISWPLGEPSL 

       130        140        150        160        170        180 
AFFDLSSTRV HRNDDIRRDQ IATLAMRSCK ITNDLEDSFA GLHRMIATEA ILRGIDLCLL 

       190        200        210        220        230        240 
PGFDLMYEVA HVQCVRLLQA AKEDISNAVV PNSALIVLME ESLMLRSSLP SMMGRNNWIP 

       250        260 
VIPPIPDVEM ESEEESDDDG FVEVD 

« Hide

References

[1]"Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses."
Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L.
Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62."
Kalveram B., Lihoradova O., Ikegami T.
J. Virol. 85:6234-6243(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X53771 Genomic RNA. Translation: CAA37788.1.
PIRMNVURV. C38552.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP21698. 26 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR024376. RVFV_non-structural.
[Graphical view]
PfamPF11073. NSs. 1 hit.
[Graphical view]
PIRSFPIRSF003956. NS-S_PhleboV. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNSS_RVFVZ
AccessionPrimary (citable) accession number: P21698
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families