P21698 (NSS_RVFVZ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-structural protein NS-S

Gene names

Name:

NSS

Organism

Rift valley fever virus (strain ZH-548 M12) (RVFV) [Reference proteome]

Taxonomic identifier

11589 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Phlebovirus › Rift valley fever virus

Virus host

Aedes [TaxID: 7158]
Bos taurus (Bovine) [TaxID: 9913]
Bos taurus x Bison bison (beefalo) [TaxID: 297284]
Camelus bactrianus (Bactrian camel) [TaxID: 9837]
Capra hircus (Goat) [TaxID: 9925]
Homo sapiens (Human) [TaxID: 9606]
Ovis aries (Sheep) [TaxID: 9940]
Phlebotomus papatasi (Sandfly) [TaxID: 29031]

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the phlebovirus NS-S protein family.

Ontologies

Keywords
Biological process	Host gene expression shutoff by virus Host transcription shutoff by virus Host-virus interaction Inhibition of host transcription initiation by virus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	suppression by virus of host DNA-dependent transcription, initiation Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	Non-structural protein NS-S		PRO_0000221979

Sequences

	Sequence		Length	Mass (Da)
	P21698 [UniParc]. Last modified May 1, 1991. Version 1. Checksum: EF2608D29CEB6C84	FASTA	265	29,903
	10 20 30 40 50 60 MDYFPVISVD LQSGRRVVSV EYFRGDGPPR IPYSMVGPCC VFLMHHRPSH EVRLRFSDFY 70 80 90 100 110 120 NVGEFPYRVG LGDFASNVAP PPAKPFQRLI DLIGHMTLSD FTRFPNLKEA ISWPLGEPSL 130 140 150 160 170 180 AFFDLSSTRV HRNDDIRRDQ IATLAMRSCK ITNDLEDSFA GLHRMIATEA ILRGIDLCLL 190 200 210 220 230 240 PGFDLMYEVA HVQCVRLLQA AKEDISNAVV PNSALIVLME ESLMLRSSLP SMMGRNNWIP 250 260 VIPPIPDVEM ESEEESDDDG FVEVD

References

[1]

"Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian Sandfly fever, and Uukuniemi viruses." Giorgi C., Accardi L., Nicoletti L., Gro M.C., Takehara K., Hilditch C., Morikawa S., Bishop D.H.L. Virology 180:738-753(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X53771 Genomic RNA. Translation: CAA37788.1.
PIR	MNVURV. C38552.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P21698. 26 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR024376. RVFV_non-structural. [Graphical view]
Pfam	PF11073. NSs. 1 hit. [Graphical view]
PIRSF	PIRSF003956. NS-S_PhleboV. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NSS_RVFVZ

Accession

Primary (citable) accession number: P21698

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1991
Last sequence update:	May 1, 1991
Last modified:	April 3, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program