##gff-version 3 P21691 UniProtKB Chain 1 654 . . . ID=PRO_0000097767;Note=Regulatory protein SIR1 P21691 UniProtKB Region 322 654 . . . Note=Sufficient for interaction with SIR4;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Region 449 587 . . . Note=ORC interacting region (OIR) P21691 UniProtKB Mutagenesis 462 464 . . . Note=No effect. EEE->AAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 466 466 . . . Note=Abolishes interaction with ORC1. V->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 469 469 . . . Note=Abolishes interaction with ORC1. R->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 470 470 . . . Note=Abolishes interaction with ORC1 and SIR4. F->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 477 477 . . . Note=Abolishes interaction with ORC1 and SIR4. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 479 479 . . . Note=Abolishes interaction with ORC1. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 480 480 . . . Note=Abolishes interaction with ORC1. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 482 483 . . . Note=No effect. EE->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 489 490 . . . Note=No effect. KD->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 498 499 . . . Note=No effect. KD->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 513 513 . . . Note=Abolishes interaction with ORC1 and SIR4. W->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 517 518 . . . Note=No effect. KK->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 534 534 . . . Note=No effect. C->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 538 540 . . . Note=Abolishes interaction with SIR4. KKK->AAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 569 569 . . . Note=No effect. C->A P21691 UniProtKB Mutagenesis 571 571 . . . Note=Abolishes interaction with ORC1 and SIR4. C->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 572 572 . . . Note=No effect. V->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 573 573 . . . Note=No effect. P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 577 578 . . . Note=Abolishes interaction with SIR4. DD->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 584 584 . . . Note=Abolishes interaction with ORC1 and SIR4. L->P%2CQ;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Mutagenesis 586 587 . . . Note=Abolishes interaction with SIR4. DD->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14701749;Dbxref=PMID:14701749 P21691 UniProtKB Beta strand 464 473 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 476 479 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Turn 480 483 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 484 486 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Helix 493 496 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Helix 499 506 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Helix 513 516 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 523 525 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Helix 530 533 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 537 543 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 547 550 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 566 575 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A P21691 UniProtKB Beta strand 577 579 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1ZBX P21691 UniProtKB Beta strand 581 586 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1Z1A