Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transcriptional activator protein DAL81

Gene

DAL81

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Positive regulation of genes required for catabolism of GABA (UGA4, UGA1, and UGA2), urea (DUR1 and DUR2), arginine and allantoin.

Miscellaneous

Present with 704 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi150 – 179Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST30

GO - Molecular functioni

GO - Biological processi

  • nitrogen catabolite activation of transcription from RNA polymerase II promoter Source: SGD
  • positive regulation of gamma-aminobutyric acid catabolic process Source: SGD
  • positive regulation of nitrogen utilization Source: GO_Central
  • positive regulation of urea catabolic process Source: SGD

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-31442-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator protein DAL81
Alternative name(s):
Regulatory protein UGA35
Gene namesi
Name:DAL81
Synonyms:DURL, UGA35
Ordered Locus Names:YIR023W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IX

Organism-specific databases

EuPathDBiFungiDB:YIR023W
SGDiS000001462 DAL81

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001149471 – 970Transcriptional activator protein DAL81Add BLAST970

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei833PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP21657
PaxDbiP21657
PRIDEiP21657

PTM databases

iPTMnetiP21657

Interactioni

Protein-protein interaction databases

BioGridi35014, 574 interactors
DIPiDIP-5733N
IntActiP21657, 8 interactors
MINTiP21657
STRINGi4932.YIR023W

Structurei

3D structure databases

ProteinModelPortaliP21657
SMRiP21657
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi24 – 50Asn-richAdd BLAST27
Compositional biasi73 – 88Poly-GlnAdd BLAST16
Compositional biasi127 – 139Asn-richAdd BLAST13
Compositional biasi227 – 237Poly-GlnAdd BLAST11

Phylogenomic databases

HOGENOMiHOG000094358
InParanoidiP21657
OMAiLREWYHS
OrthoDBiEOG092C0PA0

Family and domain databases

CDDicd00067 GAL4, 1 hit
InterProiView protein in InterPro
IPR007219 Transcription_factor_dom_fun
IPR001138 Zn2-C6_fun-type_DNA-bd
IPR036864 Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF04082 Fungal_trans, 1 hit
PF00172 Zn_clus, 1 hit
SMARTiView protein in SMART
SM00906 Fungal_trans, 1 hit
SM00066 GAL4, 1 hit
SUPFAMiSSF57701 SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463 ZN2_CY6_FUNGAL_1, 1 hit
PS50048 ZN2_CY6_FUNGAL_2, 1 hit

Sequencei

Sequence statusi: Complete.

P21657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPHQSPADN AASPTKSVKA TTKNSSTNNN VNSNNSNNNS NHDILNFNDN
60 70 80 90 100
YTTILQHLAN DHPNILREKG GSQQQQHQQQ QQQQQQQQQQ QQQQSLDTLL
110 120 130 140 150
HHYQSLLSKS DNAIAFDDNV SNSADHNGSN SNNNNNNNDI SSPGNLMGSC
160 170 180 190 200
NQCRLKKTKC NYFPDLGNCL ECETSRTKCT FSIAPNYLKR TSSGANNNMP
210 220 230 240 250
TSSNSKRMKN FEDYSNRLPS SMLYRHQQQQ QQQQQQQRIQ YPRSSFFVGP
260 270 280 290 300
ASVFDLNLTK HVRLDNVDQI QLSKTLSLRK VSPTAQFILQ DDFDTTLHSK
310 320 330 340 350
QEYEVDLVEN LVHPHGHLLV EIFFKLIHPF LPILHERVFL EKYSRSYREL
360 370 380 390 400
TAPLLASIYS LALQYWDFHP ALLGFPKPDV TAQLNNIALE TFYARVGRPK
410 420 430 440 450
LSIIQTGLLI LQCRSECHNN WVLCSSVVAL AEELGLGVEC NDWKLPKWEK
460 470 480 490 500
DLRKRLAWAV WLMDKWCALN EGRQSHLILG RNWMIKLLNF DDFPLNSPTI
510 520 530 540 550
LNSLQNDQSG SSPSSSNDVK NHQIAFGNLP IFNINPTLED FKNGTLMFQQ
560 570 580 590 600
MVSLSIILGE IMDTFYTQGS MTINKSIEQV LKLAKPLQLK LREWYHSLPK
610 620 630 640 650
NLSMSYATPQ KLNSNSTLTL AYFATEITLH RKIICALNPQ TPKELVQVCR
660 670 680 690 700
TAARTRLVAA IEFIRDLKNE HINAFWYNCS TGNLMLIGTF AALLYVTSAT
710 720 730 740 750
KEEAMIFRDY VRNYTWVLKI GSKYFDKLSN ALNNMHLLFA QIPGLLTDEP
760 770 780 790 800
VVVSPNSNIN SVNPQRSGVQ SQIPIQFNVG SPAMTEQGSP LNQWKNLPQE
810 820 830 840 850
ILQQLNSFPN GTTSTTTPVN PTSRQTQLES QGSPAINSAN NNSNNTPLPF
860 870 880 890 900
APNKSSKKTS QSSPNVTPSH MSRHPPSNTS SPRVNSSTNV NSNTQMNASP
910 920 930 940 950
LTSINETRQE SGDAADEKTA GRERTANEES STELKDDNPN SNQETSATGN
960 970
QTIKMNDDKN VTINTRETPL
Length:970
Mass (Da):109,174
Last modified:February 1, 1995 - v3
Checksum:i9FEBD271A18AFC38
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti77 – 82Missing in AAA35192 (PubMed:1999281).Curated6
Sequence conflicti465K → R in AAA35192 (PubMed:1999281).Curated1
Sequence conflicti497S → L in AAA35192 (PubMed:1999281).Curated1
Sequence conflicti507D → G in AAA35192 (PubMed:1999281).Curated1
Sequence conflicti760N → S in AAA35192 (PubMed:1999281).Curated1
Sequence conflicti785T → A in AAA34557 (PubMed:1990272).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63498 Genomic DNA Translation: AAA35192.1
M60415 Genomic DNA Translation: AAA34557.1
Z38061 Genomic DNA Translation: CAA86183.1
BK006942 Genomic DNA Translation: DAA08570.1
PIRiS48485
RefSeqiNP_012289.3, NM_001179545.3

Genome annotation databases

EnsemblFungiiYIR023W; YIR023W; YIR023W
GeneIDi854841
KEGGisce:YIR023W

Similar proteinsi

Entry informationi

Entry nameiDAL81_YEAST
AccessioniPrimary (citable) accession number: P21657
Secondary accession number(s): D6VVV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: February 1, 1995
Last modified: March 28, 2018
This is version 156 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health