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Protein

Uncharacterized MFS-type transporter YcaD

Gene

ycaD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:YCAD-MONOMER

Protein family/group databases

TCDBi2.A.1.26.1 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized MFS-type transporter YcaD
Gene namesi
Name:ycaD
Ordered Locus Names:b0898, JW0881
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11242 ycaD

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 13CytoplasmicSequence analysisAdd BLAST13
Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Topological domaini35 – 44PeriplasmicSequence analysis10
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Topological domaini66 – 78CytoplasmicSequence analysisAdd BLAST13
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 101PeriplasmicSequence analysis2
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Topological domaini123 – 130CytoplasmicSequence analysis8
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Topological domaini152 – 156PeriplasmicSequence analysis5
Transmembranei157 – 177HelicalSequence analysisAdd BLAST21
Topological domaini178 – 203CytoplasmicSequence analysisAdd BLAST26
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21
Topological domaini225 – 234PeriplasmicSequence analysis10
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Topological domaini256 – 269CytoplasmicSequence analysisAdd BLAST14
Transmembranei270 – 290HelicalSequence analysisAdd BLAST21
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Topological domaini312 – 324CytoplasmicSequence analysisAdd BLAST13
Transmembranei325 – 345HelicalSequence analysisAdd BLAST21
Topological domaini346 – 347PeriplasmicSequence analysis2
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21
Topological domaini369 – 382CytoplasmicSequence analysisAdd BLAST14

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000848891 – 382Uncharacterized MFS-type transporter YcaDAdd BLAST382

Proteomic databases

PaxDbiP21503
PRIDEiP21503

Interactioni

Protein-protein interaction databases

BioGridi4261691, 135 interactors
STRINGi316385.ECDH10B_0968

Structurei

3D structure databases

ProteinModelPortaliP21503
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108ISG Bacteria
ENOG410Y0GE LUCA
HOGENOMiHOG000280030
InParanoidiP21503
KOiK08219
OMAiIGIGDHM
PhylomeDBiP21503

Family and domain databases

CDDicd06174 MFS, 1 hit
HAMAPiMF_01149 MFS_YcaD, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR023745 MFS_YcaD
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

P21503-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYTQPVML LLSGLLLLTL AIAVLNTLVP LWLAQEHMST WQVGVVSSSY
60 70 80 90 100
FTGNLVGTLL TGYVIKRIGF NRSYYLASFI FAAGCAGLGL MIGFWSWLAW
110 120 130 140 150
RFVAGVGCAM IWVVVESALM CSGTSRNRGR LLAAYMMVYY VGTFLGQLLV
160 170 180 190 200
SKVSTELMSV LPWVTGLTLA GILPLLFTRV LNQQAENHDS TSITSMLKLR
210 220 230 240 250
QARLGVNGCI ISGIVLGSLY GLMPLYLNHK GVSNASIGFW MAVLVSAGIL
260 270 280 290 300
GQWPIGRLAD KFGRLLVLRV QVFVVILGSI AMLSQAAMAP ALFILGAAGF
310 320 330 340 350
TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF TAMLMQNFSD
360 370 380
NLLFIMIASV SFIYLLMLLR NAGHTPKPVA HV
Length:382
Mass (Da):41,432
Last modified:November 1, 1997 - v2
Checksum:i9C0F47A928B7C949
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73984.1
AP009048 Genomic DNA Translation: BAA35630.1
J03412 Genomic DNA Translation: AAA83847.1
PIRiA64829
RefSeqiNP_415418.1, NC_000913.3
WP_000109259.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73984; AAC73984; b0898
BAA35630; BAA35630; BAA35630
GeneIDi945515
KEGGiecj:JW0881
eco:b0898
PATRICifig|1411691.4.peg.1378

Similar proteinsi

Entry informationi

Entry nameiYCAD_ECOLI
AccessioniPrimary (citable) accession number: P21503
Secondary accession number(s): P75834
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health