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P21447

- MDR1A_MOUSE

UniProt

P21447 - MDR1A_MOUSE

Protein

Multidrug resistance protein 1A

Gene

Abcb1a

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 131 (01 Oct 2014)
      Sequence version 3 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.1 Publication

    Catalytic activityi

    ATP + H2O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi423 – 4308ATP 1PROSITE-ProRule annotation
    Nucleotide bindingi1066 – 10738ATP 2PROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATPase activity, coupled Source: MGI
    2. ATPase activity, coupled to transmembrane movement of substances Source: RefGenome
    3. ATP binding Source: UniProtKB-KW
    4. xenobiotic-transporting ATPase activity Source: UniProtKB-EC

    GO - Biological processi

    1. ATP catabolic process Source: GOC
    2. circadian rhythm Source: Ensembl
    3. drug transport Source: MGI
    4. lactation Source: Ensembl
    5. negative regulation of cell death Source: Ensembl
    6. response to cadmium ion Source: Ensembl
    7. response to hypoxia Source: Ensembl
    8. response to vitamin D Source: Ensembl
    9. transmembrane transport Source: RefGenome

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_196555. Abacavir transmembrane transport.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Multidrug resistance protein 1A (EC:3.6.3.44)
    Alternative name(s):
    ATP-binding cassette sub-family B member 1A
    MDR1A
    Multidrug resistance protein 3
    P-glycoprotein 3
    Gene namesi
    Name:Abcb1a
    Synonyms:Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:97570. Abcb1a.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: RefGenome
    2. intercellular canaliculus Source: MGI
    3. plasma membrane Source: Reactome

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12761276Multidrug resistance protein 1APRO_0000093336Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi83 – 831N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi87 – 871N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi90 – 901N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiP21447.
    PaxDbiP21447.
    PRIDEiP21447.

    PTM databases

    PhosphoSiteiP21447.

    Expressioni

    Gene expression databases

    ArrayExpressiP21447.
    BgeeiP21447.
    GenevestigatoriP21447.

    Interactioni

    Subunit structurei

    Interacts with PSMB5.By similarity

    Protein-protein interaction databases

    IntActiP21447. 1 interaction.
    MINTiMINT-4101695.

    Structurei

    Secondary structure

    1
    1276
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi36 – 394
    Helixi45 – 517
    Helixi55 – 595
    Helixi63 – 708
    Helixi74 – 807
    Helixi84 – 874
    Helixi93 – 11422
    Helixi122 – 13514
    Helixi139 – 15113
    Helixi167 – 17913
    Helixi189 – 1968
    Helixi211 – 22010
    Helixi228 – 24518
    Turni249 – 2513
    Helixi257 – 2615
    Helixi269 – 28214
    Helixi289 – 2935
    Helixi298 – 31114
    Helixi316 – 3194
    Beta strandi320 – 3223
    Helixi327 – 3359
    Helixi344 – 35411
    Helixi360 – 3634
    Beta strandi388 – 3958
    Beta strandi411 – 4133
    Beta strandi418 – 4214
    Helixi432 – 4354
    Turni436 – 4383
    Beta strandi446 – 4483
    Helixi454 – 4563
    Helixi459 – 4657
    Helixi480 – 4867
    Helixi493 – 50210
    Helixi506 – 5116
    Helixi515 – 5173
    Helixi532 – 54312
    Beta strandi546 – 5527
    Helixi559 – 57315
    Beta strandi577 – 5815
    Helixi585 – 5884
    Beta strandi592 – 5954
    Helixi608 – 6136
    Helixi618 – 6247
    Helixi695 – 7028
    Helixi712 – 7165
    Helixi721 – 73111
    Helixi743 – 75715
    Helixi761 – 7688
    Helixi779 – 79416
    Helixi798 – 8014
    Helixi810 – 82112
    Helixi828 – 83811
    Helixi844 – 8474
    Helixi854 – 86613
    Helixi870 – 8756
    Helixi879 – 8868
    Helixi892 – 8976
    Turni901 – 9055
    Helixi909 – 93325
    Helixi937 – 95418
    Beta strandi961 – 9633
    Helixi970 – 9778
    Beta strandi989 – 9913
    Helixi996 – 100914
    Beta strandi1013 – 10164
    Turni1024 – 10274
    Beta strandi1031 – 10344
    Beta strandi1036 – 10383
    Helixi1043 – 10453
    Beta strandi1054 – 10563
    Beta strandi1061 – 10655
    Helixi1073 – 10797
    Beta strandi1089 – 10913
    Helixi1102 – 11054
    Beta strandi1112 – 11154
    Beta strandi1120 – 11223
    Helixi1123 – 11275
    Helixi1138 – 114811
    Helixi1151 – 11544
    Turni1157 – 11593
    Helixi1160 – 11623
    Helixi1177 – 118812
    Beta strandi1194 – 11974
    Beta strandi1199 – 12013
    Helixi1204 – 121714
    Beta strandi1223 – 12264
    Helixi1232 – 12343
    Beta strandi1237 – 12426
    Beta strandi1247 – 12493
    Helixi1253 – 12586
    Helixi1263 – 12708

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3G5UX-ray3.80A/B1-1276[»]
    3G60X-ray4.40A/B1-1276[»]
    3G61X-ray4.35A/B1-1276[»]
    4KSBX-ray3.80A1-1276[»]
    4KSCX-ray4.00A1-1276[»]
    4KSDX-ray4.10A1-1276[»]
    4LSGX-ray3.80A/B1-1276[»]
    4M1MX-ray3.80A/B1-1276[»]
    4M2SX-ray4.40A/B1-1276[»]
    4M2TX-ray4.35A/B1-1276[»]
    ProteinModelPortaliP21447.
    SMRiP21447. Positions 31-626.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP21447.

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 4343CytoplasmicBy similarityAdd
    BLAST
    Topological domaini67 – 11246ExtracellularBy similarityAdd
    BLAST
    Topological domaini134 – 18249CytoplasmicBy similarityAdd
    BLAST
    Topological domaini205 – 2117ExtracellularBy similarity
    Topological domaini233 – 29058CytoplasmicBy similarityAdd
    BLAST
    Topological domaini313 – 32614ExtracellularBy similarityAdd
    BLAST
    Topological domaini349 – 707359CytoplasmicBy similarityAdd
    BLAST
    Topological domaini729 – 75224ExtracellularBy similarityAdd
    BLAST
    Topological domaini774 – 82855CytoplasmicBy similarityAdd
    BLAST
    Topological domaini850 – 8501ExtracellularBy similarity
    Topological domaini871 – 93060CytoplasmicBy similarityAdd
    BLAST
    Topological domaini954 – 96916ExtracellularBy similarityAdd
    BLAST
    Topological domaini992 – 1276285CytoplasmicBy similarityAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei44 – 6623HelicalAdd
    BLAST
    Transmembranei113 – 13321HelicalAdd
    BLAST
    Transmembranei183 – 20422HelicalAdd
    BLAST
    Transmembranei212 – 23221HelicalAdd
    BLAST
    Transmembranei291 – 31222HelicalAdd
    BLAST
    Transmembranei327 – 34822HelicalAdd
    BLAST
    Transmembranei708 – 72821HelicalAdd
    BLAST
    Transmembranei753 – 77321HelicalAdd
    BLAST
    Transmembranei829 – 84921HelicalAdd
    BLAST
    Transmembranei851 – 87020HelicalAdd
    BLAST
    Transmembranei931 – 95323HelicalAdd
    BLAST
    Transmembranei970 – 99122HelicalAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini50 – 353304ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini388 – 624237ABC transporter 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini707 – 996290ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini1031 – 1269239ABC transporter 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation
    Contains 2 ABC transporter domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1132.
    GeneTreeiENSGT00530000062896.
    HOVERGENiHBG080809.
    InParanoidiQ5I1Y5.
    KOiK05658.
    OMAiFWALISV.
    OrthoDBiEOG7Z3F4H.
    PhylomeDBiP21447.
    TreeFamiTF105193.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR003593. AAA+_ATPase.
    IPR011527. ABC1_TM_dom.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR001140. ABC_transptr_TM_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00664. ABC_membrane. 2 hits.
    PF00005. ABC_tran. 2 hits.
    [Graphical view]
    SMARTiSM00382. AAA. 2 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    SSF90123. SSF90123. 2 hits.
    PROSITEiPS50929. ABC_TM1F. 2 hits.
    PS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P21447-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELEEDLKGR ADKNFSKMGK KSKKEKKEKK PAVSVLTMFR YAGWLDRLYM     50
    LVGTLAAIIH GVALPLMMLI FGDMTDSFAS VGNVSKNSTN MSEADKRAMF 100
    AKLEEEMTTY AYYYTGIGAG VLIVAYIQVS FWCLAAGRQI HKIRQKFFHA 150
    IMNQEIGWFD VHDVGELNTR LTDDVSKINE GIGDKIGMFF QAMATFFGGF 200
    IIGFTRGWKL TLVILAISPV LGLSAGIWAK ILSSFTDKEL HAYAKAGAVA 250
    EEVLAAIRTV IAFGGQKKEL ERYNNNLEEA KRLGIKKAIT ANISMGAAFL 300
    LIYASYALAF WYGTSLVISK EYSIGQVLTV FFSVLIGAFS VGQASPNIEA 350
    FANARGAAYE VFKIIDNKPS IDSFSKSGHK PDNIQGNLEF KNIHFSYPSR 400
    KEVQILKGLN LKVKSGQTVA LVGNSGCGKS TTVQLMQRLY DPLDGMVSID 450
    GQDIRTINVR YLREIIGVVS QEPVLFATTI AENIRYGRED VTMDEIEKAV 500
    KEANAYDFIM KLPHQFDTLV GERGAQLSGG QKQRIAIARA LVRNPKILLL 550
    DEATSALDTE SEAVVQAALD KAREGRTTIV IAHRLSTVRN ADVIAGFDGG 600
    VIVEQGNHDE LMREKGIYFK LVMTQTAGNE IELGNEACKS KDEIDNLDMS 650
    SKDSGSSLIR RRSTRKSICG PHDQDRKLST KEALDEDVPP ASFWRILKLN 700
    STEWPYFVVG IFCAIINGGL QPAFSVIFSK VVGVFTNGGP PETQRQNSNL 750
    FSLLFLILGI ISFITFFLQG FTFGKAGEIL TKRLRYMVFK SMLRQDVSWF 800
    DDPKNTTGAL TTRLANDAAQ VKGATGSRLA VIFQNIANLG TGIIISLIYG 850
    WQLTLLLLAI VPIIAIAGVV EMKMLSGQAL KDKKELEGSG KIATEAIENF 900
    RTVVSLTREQ KFETMYAQSL QIPYRNAMKK AHVFGITFSF TQAMMYFSYA 950
    ACFRFGAYLV TQQLMTFENV LLVFSAIVFG AMAVGQVSSF APDYAKATVS 1000
    ASHIIRIIEK TPEIDSYSTQ GLKPNMLEGN VQFSGVVFNY PTRPSIPVLQ 1050
    GLSLEVKKGQ TLALVGSSGC GKSTVVQLLE RFYDPMAGSV FLDGKEIKQL 1100
    NVQWLRAQLG IVSQEPILFD CSIAENIAYG DNSRVVSYEE IVRAAKEANI 1150
    HQFIDSLPDK YNTRVGDKGT QLSGGQKQRI AIARALVRQP HILLLDEATS 1200
    ALDTESEKVV QEALDKAREG RTCIVIAHRL STIQNADLIV VIQNGKVKEH 1250
    GTHQQLLAQK GIYFSMVSVQ AGAKRS 1276
    Length:1,276
    Mass (Da):140,647
    Last modified:June 16, 2009 - v3
    Checksum:i542E101DF18DDC52
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti526 – 5272QL → HV in AAA39514. (PubMed:1972547)Curated
    Sequence conflicti526 – 5272QL → HV in AAA03243. (PubMed:2473069)Curated
    Sequence conflicti939 – 9391S → F in AAA39517. (PubMed:1969610)Curated
    Sequence conflicti1036 – 10361V → F in AAA39517. (PubMed:1969610)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M30697 mRNA. Translation: AAA39517.1.
    M33581 mRNA. Translation: AAA39514.1.
    M33580 Genomic DNA. Translation: AAA39518.1.
    AY864315 mRNA. Translation: AAW56448.1.
    CH466600 Genomic DNA. Translation: EDL14677.1.
    M24417 mRNA. Translation: AAA03243.1.
    CCDSiCCDS19084.1.
    PIRiA34175. DVMS1A.
    A34786.
    RefSeqiNP_035206.2. NM_011076.2.
    XP_006503618.1. XM_006503555.1.
    XP_006503619.1. XM_006503556.1.
    UniGeneiMm.207354.

    Genome annotation databases

    EnsembliENSMUST00000047753; ENSMUSP00000041204; ENSMUSG00000040584.
    GeneIDi18671.
    KEGGimmu:18671.
    UCSCiuc008wkl.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M30697 mRNA. Translation: AAA39517.1 .
    M33581 mRNA. Translation: AAA39514.1 .
    M33580 Genomic DNA. Translation: AAA39518.1 .
    AY864315 mRNA. Translation: AAW56448.1 .
    CH466600 Genomic DNA. Translation: EDL14677.1 .
    M24417 mRNA. Translation: AAA03243.1 .
    CCDSi CCDS19084.1.
    PIRi A34175. DVMS1A.
    A34786.
    RefSeqi NP_035206.2. NM_011076.2.
    XP_006503618.1. XM_006503555.1.
    XP_006503619.1. XM_006503556.1.
    UniGenei Mm.207354.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3G5U X-ray 3.80 A/B 1-1276 [» ]
    3G60 X-ray 4.40 A/B 1-1276 [» ]
    3G61 X-ray 4.35 A/B 1-1276 [» ]
    4KSB X-ray 3.80 A 1-1276 [» ]
    4KSC X-ray 4.00 A 1-1276 [» ]
    4KSD X-ray 4.10 A 1-1276 [» ]
    4LSG X-ray 3.80 A/B 1-1276 [» ]
    4M1M X-ray 3.80 A/B 1-1276 [» ]
    4M2S X-ray 4.40 A/B 1-1276 [» ]
    4M2T X-ray 4.35 A/B 1-1276 [» ]
    ProteinModelPortali P21447.
    SMRi P21447. Positions 31-626.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P21447. 1 interaction.
    MINTi MINT-4101695.

    Chemistry

    BindingDBi P21447.
    ChEMBLi CHEMBL2573.

    PTM databases

    PhosphoSitei P21447.

    Proteomic databases

    MaxQBi P21447.
    PaxDbi P21447.
    PRIDEi P21447.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000047753 ; ENSMUSP00000041204 ; ENSMUSG00000040584 .
    GeneIDi 18671.
    KEGGi mmu:18671.
    UCSCi uc008wkl.1. mouse.

    Organism-specific databases

    CTDi 18671.
    MGIi MGI:97570. Abcb1a.

    Phylogenomic databases

    eggNOGi COG1132.
    GeneTreei ENSGT00530000062896.
    HOVERGENi HBG080809.
    InParanoidi Q5I1Y5.
    KOi K05658.
    OMAi FWALISV.
    OrthoDBi EOG7Z3F4H.
    PhylomeDBi P21447.
    TreeFami TF105193.

    Enzyme and pathway databases

    Reactomei REACT_196555. Abacavir transmembrane transport.

    Miscellaneous databases

    EvolutionaryTracei P21447.
    NextBioi 294686.
    PROi P21447.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P21447.
    Bgeei P21447.
    Genevestigatori P21447.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR003593. AAA+_ATPase.
    IPR011527. ABC1_TM_dom.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR001140. ABC_transptr_TM_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00664. ABC_membrane. 2 hits.
    PF00005. ABC_tran. 2 hits.
    [Graphical view ]
    SMARTi SM00382. AAA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    SSF90123. SSF90123. 2 hits.
    PROSITEi PS50929. ABC_TM1F. 2 hits.
    PS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities."
      Devault A., Gros P.
      Mol. Cell. Biol. 10:1652-1663(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells."
      Hsu S.I.H., Cohen D., Kirschner L.S., Lothstein L., Hartstein M., Horwitz S.B.
      Mol. Cell. Biol. 10:3596-3606(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
    3. "Heterologus expression of mouse mdr1a (Abcb1a), (P-glycoprotein), using the insect cell baculovirus expression system."
      Pimprale S.S., Xiao G., Patten C., Crespi C.
      Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: BALB/c.
    4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes."
      Hsu S.I.H., Lothstein L., Horwitz S.B.
      J. Biol. Chem. 264:12053-12062(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 173-1276.
      Strain: BALB/c.
    6. Lubec G., Sunyer B., Chen W.-Q.
      Submitted (JAN-2009) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 273-282, IDENTIFICATION BY MASS SPECTROMETRY.
      Strain: OF1.
      Tissue: Hippocampus.
    7. "Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding."
      Aller S.G., Yu J., Ward A., Weng Y., Chittaboina S., Zhuo R., Harrell P.M., Trinh Y.T., Zhang Q., Urbatsch I.L., Chang G.
      Science 323:1718-1722(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.8 ANGSTROMS) IN COMPLEXES WITH INHIBITORS, FUNCTION, TOPOLOGY.

    Entry informationi

    Entry nameiMDR1A_MOUSE
    AccessioniPrimary (citable) accession number: P21447
    Secondary accession number(s): Q5I1Y5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1991
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 131 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    In mouse the MDR gene family includes three or more related but distinct cellular genes.

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3