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Protein

Uncharacterized protein YcaC

Gene

ycaC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei118 – 1181Sequence analysis

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciEcoCyc:EG11241-MONOMER.
ECOL316407:JW0880-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YcaC
Gene namesi
Name:ycaC
Ordered Locus Names:b0897, JW0880
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11241. ycaC.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: UniProtKB
  • membrane Source: UniProtKB
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208Uncharacterized protein YcaCPRO_0000168753Add
BLAST

Proteomic databases

EPDiP21367.
PaxDbiP21367.
PRIDEiP21367.

Interactioni

Subunit structurei

Homooctamer composed of two tetrameric rings.

Protein-protein interaction databases

BioGridi4259587. 14 interactions.
DIPiDIP-11462N.
IntActiP21367. 3 interactions.
STRINGi511145.b0897.

Structurei

Secondary structure

1
208
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi12 – 187Combined sources
Helixi24 – 274Combined sources
Helixi33 – 4917Combined sources
Beta strandi54 – 607Combined sources
Turni61 – 655Combined sources
Helixi70 – 756Combined sources
Beta strandi81 – 866Combined sources
Helixi90 – 923Combined sources
Helixi94 – 1029Combined sources
Beta strandi106 – 1149Combined sources
Helixi115 – 1195Combined sources
Helixi120 – 1289Combined sources
Beta strandi132 – 1365Combined sources
Helixi145 – 15814Combined sources
Beta strandi161 – 1633Combined sources
Helixi165 – 1739Combined sources
Helixi176 – 1783Combined sources
Helixi180 – 19011Combined sources
Helixi192 – 20413Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YACX-ray1.80A/B1-208[»]
ProteinModelPortaliP21367.
SMRiP21367. Positions 2-205.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP21367.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105CHJ. Bacteria.
COG1335. LUCA.
HOGENOMiHOG000167093.
InParanoidiP21367.
OMAiMYPDAPL.
OrthoDBiEOG632D6N.
PhylomeDBiP21367.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
InterProiIPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.

Sequencei

Sequence statusi: Complete.

P21367-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPYVRLDK NDAAVLLVDH QAGLLSLVRD IEPDKFKNNV LALGDLAKYF
60 70 80 90 100
NLPTILTTSF ETGPNGPLVP ELKAQFPDTP YIARPGNINA WDNEDFVKAV
110 120 130 140 150
KATGKKQLII AGVVTEVCVA FPALSAIEEG FDVFVVTDAS GTFNEITRHS
160 170 180 190 200
AWDRLSQAGA QLMTWFGVAC ELHRDWRNDI EGLATLFSNH IPDYRNLMTS

YDTLTKQK
Length:208
Mass (Da):23,100
Last modified:May 1, 1991 - v1
Checksum:i5FB5A4F0CC049BEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03412 Genomic DNA. Translation: AAA83846.1.
U00096 Genomic DNA. Translation: AAC73983.1.
AP009048 Genomic DNA. Translation: BAA35629.1.
PIRiS09671.
RefSeqiNP_415417.1. NC_000913.3.
WP_000165879.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73983; AAC73983; b0897.
BAA35629; BAA35629; BAA35629.
GeneIDi945512.
KEGGiecj:JW0880.
eco:b0897.
PATRICi32117005. VBIEscCol129921_0927.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03412 Genomic DNA. Translation: AAA83846.1.
U00096 Genomic DNA. Translation: AAC73983.1.
AP009048 Genomic DNA. Translation: BAA35629.1.
PIRiS09671.
RefSeqiNP_415417.1. NC_000913.3.
WP_000165879.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YACX-ray1.80A/B1-208[»]
ProteinModelPortaliP21367.
SMRiP21367. Positions 2-205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259587. 14 interactions.
DIPiDIP-11462N.
IntActiP21367. 3 interactions.
STRINGi511145.b0897.

Proteomic databases

EPDiP21367.
PaxDbiP21367.
PRIDEiP21367.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73983; AAC73983; b0897.
BAA35629; BAA35629; BAA35629.
GeneIDi945512.
KEGGiecj:JW0880.
eco:b0897.
PATRICi32117005. VBIEscCol129921_0927.

Organism-specific databases

EchoBASEiEB1223.
EcoGeneiEG11241. ycaC.

Phylogenomic databases

eggNOGiENOG4105CHJ. Bacteria.
COG1335. LUCA.
HOGENOMiHOG000167093.
InParanoidiP21367.
OMAiMYPDAPL.
OrthoDBiEOG632D6N.
PhylomeDBiP21367.

Enzyme and pathway databases

BioCyciEcoCyc:EG11241-MONOMER.
ECOL316407:JW0880-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP21367.
PROiP21367.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
InterProiIPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the dmsABC operon encoding the anaerobic dimethylsulphoxide reductase of Escherichia coli."
    Bilous P.T., Cole S.T., Anderson W.F., Weiner J.H.
    Mol. Microbiol. 2:785-795(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / C600 / ATCC 23724 / DSM 3925 / LMG 3041 / NCIB 10222.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "The 1.8-A crystal structure of the ycaC gene product from Escherichia coli reveals an octameric hydrolase of unknown specificity."
    Colovos C., Cascio D., Yeates T.O.
    Structure 6:1329-1337(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).

Entry informationi

Entry nameiYCAC_ECOLI
AccessioniPrimary (citable) accession number: P21367
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: March 16, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.