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Protein

Probable hydrolase YcaC

Gene

ycaC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei118Sequence analysis1

GO - Molecular functioni

  • hydrolase activity Source: UniProtKB-KW
  • identical protein binding Source: EcoCyc
  • lyase activity Source: UniProtKB-KW

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Lyase

Enzyme and pathway databases

BioCyciEcoCyc:EG11241-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable hydrolase YcaC (EC:4.-.-.-)
Gene namesi
Name:ycaC
Ordered Locus Names:b0897, JW0880
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11241. ycaC.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: UniProtKB
  • membrane Source: UniProtKB

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001687531 – 208Probable hydrolase YcaCAdd BLAST208

Proteomic databases

PaxDbiP21367.
PRIDEiP21367.

Interactioni

Subunit structurei

Homooctamer composed of two tetrameric rings.1 Publication

GO - Molecular functioni

  • identical protein binding Source: EcoCyc

Protein-protein interaction databases

BioGridi4259587. 14 interactors.
DIPiDIP-11462N.
IntActiP21367. 3 interactors.
STRINGi316385.ECDH10B_0967.

Structurei

Secondary structure

1208
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi12 – 18Combined sources7
Helixi24 – 27Combined sources4
Helixi33 – 49Combined sources17
Beta strandi54 – 60Combined sources7
Turni61 – 65Combined sources5
Helixi70 – 75Combined sources6
Beta strandi81 – 86Combined sources6
Helixi90 – 92Combined sources3
Helixi94 – 102Combined sources9
Beta strandi106 – 114Combined sources9
Helixi115 – 119Combined sources5
Helixi120 – 128Combined sources9
Beta strandi132 – 136Combined sources5
Helixi145 – 158Combined sources14
Beta strandi161 – 163Combined sources3
Helixi165 – 173Combined sources9
Helixi176 – 178Combined sources3
Helixi180 – 190Combined sources11
Helixi192 – 204Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YACX-ray1.80A/B1-208[»]
ProteinModelPortaliP21367.
SMRiP21367.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP21367.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105CHJ. Bacteria.
COG1335. LUCA.
HOGENOMiHOG000167093.
InParanoidiP21367.
PhylomeDBiP21367.

Family and domain databases

InterProiView protein in InterPro
IPR000868. Isochorismatase-like.
PfamiView protein in Pfam
PF00857. Isochorismatase. 1 hit.
SUPFAMiSSF52499. SSF52499. 1 hit.

Sequencei

Sequence statusi: Complete.

P21367-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPYVRLDK NDAAVLLVDH QAGLLSLVRD IEPDKFKNNV LALGDLAKYF
60 70 80 90 100
NLPTILTTSF ETGPNGPLVP ELKAQFPDTP YIARPGNINA WDNEDFVKAV
110 120 130 140 150
KATGKKQLII AGVVTEVCVA FPALSAIEEG FDVFVVTDAS GTFNEITRHS
160 170 180 190 200
AWDRLSQAGA QLMTWFGVAC ELHRDWRNDI EGLATLFSNH IPDYRNLMTS

YDTLTKQK
Length:208
Mass (Da):23,100
Last modified:May 1, 1991 - v1
Checksum:i5FB5A4F0CC049BEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J03412 Genomic DNA. Translation: AAA83846.1.
U00096 Genomic DNA. Translation: AAC73983.1.
AP009048 Genomic DNA. Translation: BAA35629.1.
PIRiS09671.
RefSeqiNP_415417.1. NC_000913.3.
WP_000165879.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73983; AAC73983; b0897.
BAA35629; BAA35629; BAA35629.
GeneIDi945512.
KEGGiecj:JW0880.
eco:b0897.
PATRICifig|1411691.4.peg.1380.

Similar proteinsi

Entry informationi

Entry nameiYCAC_ECOLI
AccessioniPrimary (citable) accession number: P21367
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: August 30, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references