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P21339 (MSB1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Morphogenesis-related protein MSB1
Alternative name(s):
Multicopy suppressor of bud emergence 1
Gene names
Name:MSB1
Ordered Locus Names:YOR188W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length1137 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May play a role in polarity establishment and bud formation. The MSB1 gene may be functionally redundant.

Miscellaneous

Present with 172 molecules/cell in log phase SD medium.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11371137Morphogenesis-related protein MSB1
PRO_0000096588

Amino acid modifications

Modified residue5381Phosphoserine Ref.5 Ref.7
Modified residue7761Phosphoserine Ref.7
Modified residue8161Phosphoserine Ref.5

Sequences

Sequence LengthMass (Da)Tools
P21339 [UniParc].

Last modified May 1, 1991. Version 1.
Checksum: 59CDD6E0F1E43F8A

FASTA1,137129,971
        10         20         30         40         50         60 
MNDMAKPLPT PPTAEIRKSR SNSPKKAQKT NLSPNKNQNN EKNVPRSNGR TKNEHNSMDD 

        70         80         90        100        110        120 
EEFEFFHQFS REKVKGVIHV ITAELKEKGP DVEFLMIPFR PEQTNDKLLT LLNQLFPLGN 

       130        140        150        160        170        180 
GQPVNEKKQL RIVSKADVWT LFQCLKYIWC RLPNSEIIGW KSYLEFKFRE EDKKFPRKSF 

       190        200        210        220        230        240 
LEIMPQCLAS PNHASIVYDF FDLIISISSN SRVNKMSARK ISKMCAIWAF SKQIPNSDIQ 

       250        260        270        280        290        300 
DYDFESAAMK SFAPNNSIQD GLDQWIPASD AMFHLLLAFL RSFVPQDLES AKLPRTLKSL 

       310        320        330        340        350        360 
LFNNQYPPRK STAYTSETIL TIPLVTLKTD VFSRKPWQLL ERCNDLLDFS DHDAFEARED 

       370        380        390        400        410        420 
YALLKSLFRK KNTVEGISRK MSQESRRLMK AMSTKHSTFQ PGWAPRECIE NISHLKECIE 

       430        440        450        460        470        480 
VKRLDIDDYF IWTWLSSLSF EQTSEKKKIF GRSIILEFEF DGFKKWVVFQ ECDITLDYNK 

       490        500        510        520        530        540 
KGQLKKKTSA QSPTTEKELP PDDFELEDPP LSKSPTLSQT YKKFQAEVPQ QSTVRRDSAP 

       550        560        570        580        590        600 
DNQGIYHTVI SKNALTKNKH NVNLHSFEHK ISKWNPLNNL RKKSGSNSSS SSFEEKSKDA 

       610        620        630        640        650        660 
PIREEYHTNK NHKSKKEERV LSQFSTLNPD EYQLPVIETG SSNFKIEIPE LMYEHDDDDS 

       670        680        690        700        710        720 
DKLKNSQKRA TDSAIEELNG MVEEMMINEP DDVKISITEA ETFESLTKFD QYKPSNITDD 

       730        740        750        760        770        780 
DLQSSHSSAV HSLKLSTNTN DSCADSSKYT ADRKLAEPRK ISEESKVNDD SSSYYSPNIN 

       790        800        810        820        830        840 
NLPASRMPSQ PTYSNSDSKK AFTNESRLNV LQGAVSPSQQ VTPKPYKNAP GDCVSPVQQK 

       850        860        870        880        890        900 
YYQNDRRNEM SPASAPVPPS AYSPARSPQF STNSAGFKQN TINVPVGYND PAHVLANQPH 

       910        920        930        940        950        960 
MTYRDQHNYP SHQQKQRPFQ NNIVPPELKS RNQRADASPI PQHMVPVKQG VPNLPSNVPL 

       970        980        990       1000       1010       1020 
YQQMERMNPN HQHPVNTYKV TQPPYHNNTT NAYGNSRAGN AHMLDGKWSN NPPQMVPKGV 

      1030       1040       1050       1060       1070       1080 
RPNQYPQQHV NRYSPQAQPV VPAEYYNGPP PMRAPPMMSH MVPAQEPIRY TAGANRRSFP 

      1090       1100       1110       1120       1130 
QGMQQNAYSV PAQPMGAVNS EFYLPEAPQG NKLHGNINKR QERKKLYDNI RSGNFGI 

« Hide

References

« Hide 'large scale' references
[1]"Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae."
Bender A., Pringle J.R.
Mol. Cell. Biol. 11:1295-1305(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-538 AND SER-816, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ADR376.
[6]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[7]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-538 AND SER-776, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M37767 Genomic DNA. Translation: AAA34797.1.
Z75096 Genomic DNA. Translation: CAA99397.1.
BK006948 Genomic DNA. Translation: DAA10960.1.
PIRS13759.
RefSeqNP_014831.3. NM_001183607.3.

3D structure databases

ProteinModelPortalP21339.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34583. 33 interactions.
DIPDIP-2687N.
IntActP21339. 3 interactions.
MINTMINT-582498.
STRING4932.YOR188W.

Proteomic databases

PaxDbP21339.
PeptideAtlasP21339.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR188W; YOR188W; YOR188W.
GeneID854360.
KEGGsce:YOR188W.

Organism-specific databases

CYGDYOR188w.
SGDS000005714. MSB1.

Phylogenomic databases

eggNOGNOG39513.
HOGENOMHOG000113660.
OrthoDBEOG7P8PH5.

Enzyme and pathway databases

BioCycYEAST:G3O-33698-MONOMER.

Gene expression databases

GenevestigatorP21339.

Family and domain databases

InterProIPR012965. DUF1708.
[Graphical view]
PfamPF08101. DUF1708. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio976467.

Entry information

Entry nameMSB1_YEAST
AccessionPrimary (citable) accession number: P21339
Secondary accession number(s): D6W2P4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: March 19, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD