P21270 (LY_BPSF6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Putative lysozyme EC=3.2.1.17
Organism	Bacillus phage SF6 (Bacteriophage SF6)
Taxonomic identifier	10773 [NCBI]
Taxonomic lineage	Viruses › dsDNA viruses, no RNA stage › Caudovirales › Siphoviridae › unclassified Siphoviridae
Virus host	Bacillus subtilis [TaxID: 1423]

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Sequence similarities	Belongs to the reoviridae sigma-1 protein family.
Caution	There is an almost complete sequence identity between the two-thirds of reovirus type 3 sigma-1 protein and the reported sequence of phage SF6 lysozyme. In the absence of further study on SF6, it is impossible to rule out the possibility that the displayed sequence might come from a contaminant. This might therefore not represent the real SF6 lysozyme sequence.

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW viral attachment to host cell Inferred from electronic annotation. Source: InterPro viral infectious cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Putative lysozyme		PRO_0000106626

Sequences

	Sequence		Length	Mass (Da)
	P21270 [UniParc]. Last modified May 1, 1991. Version 1. Checksum: 10DF518D4C7DB6A9	FASTA	316	34,124
	10 20 30 40 50 60 MDPRLREEVV RLIIALTSDN GASLSKRLQS RVSALEKTSQ IHSDTILRIT QGLDDANKRI 70 80 90 100 110 120 IALEQSRDDL VASVSDAQLA ISRLESSIGA LQTVVNGLDS SVTQLGARVG QLETGLADVR 130 140 150 160 170 180 VDHDNLVARV DTAERNIGSL TTELSTLTLR VTSIQADFES RISTLERTAV TSAGAPLSIR 190 200 210 220 230 240 NNRITMGLND GLTLSGNNLA IRLPGNTGLN IQNGGLQFRF NTDQFQIVNN NLTLKTTVFD 250 260 270 280 290 300 SINSRIGATE QSYVASAVTP LRLNSSTKVL DMLIDMSTLE INSSGQLTVR STSPNLRYPI 310 ADVSGGIGMS PNYRFR

References

[1]	"Molecular cloning and sequencing of lysozyme gene of bacteriophage SF6 of Bacillus subtilis." Verma M. Curr. Microbiol. 13:299-301(1986) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M35825 Genomic DNA. Translation: AAA32595.1.
PIR	S25234.
3D structure databases
ProteinModelPortal	P21270.
SMR	P21270. Positions 250-316.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.10.25.20. 1 hit.
InterPro	IPR009013. Attachment_protein_shaft_dom. IPR002592. Vir_attach_sigma1_reovir. [Graphical view]
Pfam	PF01664. Reo_sigma1. 1 hit. [Graphical view]
SUPFAM	SSF51225. Viral_att_shaft. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LY_BPSF6

Accession

Primary (citable) accession number: P21270

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 1991
Last sequence update:	May 1, 1991
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program