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Protein

Oligogalacturonate lyase

Gene

ogl

Organism
Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in degradation of pectin, which causes soft-rod disease in plants.

Catalytic activityi

4-(4-deoxy-beta-D-galact-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.

Pathwayi: pectin degradation

This protein is involved in step 3 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase A (pemA), Pectinesterase B (pemB)
  2. Pectate lyase L (pelL), Pectate lyase E (pelE), Pectate lyase A (pelA)
  3. Oligogalacturonate lyase (ogl)
  4. 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (kduI)
  5. 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (kduD)
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciDDAD198628:GHFQ-2489-MONOMER.
MetaCyc:MONOMER-15657.
UniPathwayiUPA00545; UER00825.

Protein family/group databases

CAZyiPL22. Polysaccharide Lyase Family 22.

Names & Taxonomyi

Protein namesi
Recommended name:
Oligogalacturonate lyase (EC:4.2.2.6)
Gene namesi
Name:ogl
Ordered Locus Names:Dda3937_03686
OrganismiDickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Taxonomic identifieri198628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
Proteomesi
  • UP000006859 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 388388Oligogalacturonate lyasePRO_0000058034Add
BLAST

Expressioni

Inductioni

By galacturonate and polygalacturonate, and subjected to catabolite repression.

Interactioni

Protein-protein interaction databases

STRINGi198628.Dda3937_03686.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105CAZ. Bacteria.
COG0823. LUCA.
HOGENOMiHOG000219311.
KOiK01730.
OMAiHLMSNFD.
OrthoDBiPOG091H0XA8.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR027946. Ogl_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF14583. Pectate_lyase22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P21258-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGKKLSFS FHTYQDSVTG TEVVRLTPPD VICHRNYFYQ KCFSNDGSKL
60 70 80 90 100
LFGGAFDGPW NYYLLDLKTQ QATQLTEGTG DNTFGGFLSP DDDALYYVKN
110 120 130 140 150
VRNLMRVDLN TLEETNIYQV PDDWVGYGTW VANSDCTKMV GIEIKKEDWK
160 170 180 190 200
PLTDWKKFQE FYFTNPCCRL IRIDLKTGEA TTILKENQWL GHPIYRPGDD
210 220 230 240 250
NTVAFCHEGP HDLVDARMWF INEDGSNMRK VKEHAPGESC THEFWVPNGS
260 270 280 290 300
ALAYVSYLKG STNRFICSVD PVTLENRQLT EMPPCSHLMS NYDGTLMVGD
310 320 330 340 350
GCNAPVDVKD DGGYKIENDP FLYVFNMKTG KHFQVAQHNT SWEVLEGDRQ
360 370 380
VTHPHPSFTP DDKHILFTSD VDGKPALYLA KVPDSVWQ
Length:388
Mass (Da):44,186
Last modified:November 30, 2010 - v2
Checksum:i6E0C73737E32A089
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti316 – 3161I → T in AAA24825 (PubMed:2695393).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33583 Genomic DNA. Translation: AAA24825.1.
CP002038 Genomic DNA. Translation: ADM98639.1.
PIRiJQ0189.
RefSeqiWP_013318086.1. NC_014500.1.

Genome annotation databases

EnsemblBacteriaiADM98639; ADM98639; Dda3937_03686.
GeneIDi9733874.
KEGGiddd:Dda3937_03686.
PATRICi42317192. VBIDicDad25310_2418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33583 Genomic DNA. Translation: AAA24825.1.
CP002038 Genomic DNA. Translation: ADM98639.1.
PIRiJQ0189.
RefSeqiWP_013318086.1. NC_014500.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198628.Dda3937_03686.

Protein family/group databases

CAZyiPL22. Polysaccharide Lyase Family 22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADM98639; ADM98639; Dda3937_03686.
GeneIDi9733874.
KEGGiddd:Dda3937_03686.
PATRICi42317192. VBIDicDad25310_2418.

Phylogenomic databases

eggNOGiENOG4105CAZ. Bacteria.
COG0823. LUCA.
HOGENOMiHOG000219311.
KOiK01730.
OMAiHLMSNFD.
OrthoDBiPOG091H0XA8.

Enzyme and pathway databases

UniPathwayiUPA00545; UER00825.
BioCyciDDAD198628:GHFQ-2489-MONOMER.
MetaCyc:MONOMER-15657.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR027946. Ogl_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF14583. Pectate_lyase22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOGL_DICD3
AccessioniPrimary (citable) accession number: P21258
Secondary accession number(s): E0SDE7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: November 30, 2010
Last modified: September 7, 2016
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.