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Protein

Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein

Gene

braC

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the high-affinity leucine, isoleucine, valine transport system I (LIV-I), which is operative without Na+ and is specific for alanine and threonine, in addition to branched-chain amino acids.1 Publication

GO - Biological processi

  • branched-chain amino acid transport Source: PseudoCAP
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Protein family/group databases

TCDBi3.A.1.4.8. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein
Short name:
LIVAT-BP
Short name:
Leu/Ile/Val/Thr/Ala-binding protein
Gene namesi
Name:braC
Ordered Locus Names:PA1074
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA1074.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 26261 PublicationAdd
BLAST
Chaini27 – 373347Leucine-, isoleucine-, valine-, threonine-, and alanine-binding proteinPRO_0000017698Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi80 ↔ 105

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP21175.
PRIDEiP21175.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA1074.

Structurei

3D structure databases

ProteinModelPortaliP21175.
SMRiP21175. Positions 28-371.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the leucine-binding protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105CP9. Bacteria.
COG0683. LUCA.
HOGENOMiHOG000130989.
InParanoidiP21175.
KOiK01999.
OMAiVYDDACD.
PhylomeDBiP21175.

Family and domain databases

InterProiIPR028081. Leu-bd.
IPR000709. Leu_Ile_Val-bd.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF13458. Peripla_BP_6. 1 hit.
[Graphical view]
PRINTSiPR00337. LEUILEVALBP.
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P21175-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKGTQRLSR LFAAMAIAGF ASYSMAADTI KIALAGPVTG PVAQYGDMQR
60 70 80 90 100
AGALMAIEQI NKAGGVNGAQ LEGVIYDDAC DPKQAVAVAN KVVNDGVKFV
110 120 130 140 150
VGHVCSSSTQ PATDIYEDEG VLMITPSATA PEITSRGYKL IFRTIGLDNM
160 170 180 190 200
QGPVAGKFIA ERYKDKTIAV LHDKQQYGEG IATEVKKTVE DAGIKVAVFE
210 220 230 240 250
GLNAGDKDFN ALISKLKKAG VQFVYFGGYH PEMGLLLRQA KQAGLDARFM
260 270 280 290 300
GPEGVGNSEI TAIAGDASEG MLATLPRAFE QDPKNKALID AFKAKNQDPS
310 320 330 340 350
GIFVLPAYSA VTVIAKGIEK AGEADPEKVA EALRANTFET PTGNLGFDEK
360 370
GDLKNFDFTV YEWHKDATRT EVK
Length:373
Mass (Da):39,769
Last modified:December 8, 2000 - v2
Checksum:i105188ADDEDEE63B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti165 – 1651D → V in AAA88430 (PubMed:2509433).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31071 Genomic DNA. Translation: AAA88430.1.
D90223 Genomic DNA. Translation: BAA14254.1.
AE004091 Genomic DNA. Translation: AAG04463.1.
PIRiA36125.
RefSeqiNP_249765.1. NC_002516.2.
WP_003082136.1. NZ_ASJY01000142.1.

Genome annotation databases

EnsemblBacteriaiAAG04463; AAG04463; PA1074.
GeneIDi878501.
KEGGipae:PA1074.
PATRICi19836452. VBIPseAer58763_1112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31071 Genomic DNA. Translation: AAA88430.1.
D90223 Genomic DNA. Translation: BAA14254.1.
AE004091 Genomic DNA. Translation: AAG04463.1.
PIRiA36125.
RefSeqiNP_249765.1. NC_002516.2.
WP_003082136.1. NZ_ASJY01000142.1.

3D structure databases

ProteinModelPortaliP21175.
SMRiP21175. Positions 28-371.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA1074.

Protein family/group databases

TCDBi3.A.1.4.8. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP21175.
PRIDEiP21175.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG04463; AAG04463; PA1074.
GeneIDi878501.
KEGGipae:PA1074.
PATRICi19836452. VBIPseAer58763_1112.

Organism-specific databases

PseudoCAPiPA1074.

Phylogenomic databases

eggNOGiENOG4105CP9. Bacteria.
COG0683. LUCA.
HOGENOMiHOG000130989.
InParanoidiP21175.
KOiK01999.
OMAiVYDDACD.
PhylomeDBiP21175.

Family and domain databases

InterProiIPR028081. Leu-bd.
IPR000709. Leu_Ile_Val-bd.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF13458. Peripla_BP_6. 1 hit.
[Graphical view]
PRINTSiPR00337. LEUILEVALBP.
SUPFAMiSSF53822. SSF53822. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiBRAC_PSEAE
AccessioniPrimary (citable) accession number: P21175
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: December 8, 2000
Last modified: September 7, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.