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P21154

- GLNA_METVO

UniProt

P21154 - GLNA_METVO

Protein

Glutamine synthetase

Gene

glnA

Organism
Methanococcus voltae
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 May 1991)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro
    2. nitrogen fixation Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine synthetase (EC:6.3.1.2)
    Short name:
    GS
    Alternative name(s):
    Glutamate--ammonia ligase
    Gene namesi
    Name:glnA
    OrganismiMethanococcus voltae
    Taxonomic identifieri2188 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 446446Glutamine synthetasePRO_0000153207Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP21154.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Family and domain databases

    Gene3Di3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR004809. Gln_synth_I.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    TIGRFAMsiTIGR00653. GlnA. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P21154-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSLEMALEY IKINNVKFLR FQFVDIHGEP KNIAYPVKLG TADGEEELMG    50
    VLENGLFFDG SSIEGFVEIE DSDMVLKPDL STLSVLPWRP SEKSVARIIC 100
    DVYRKNGKPF EGDPRGCLKR VLAEFKEEFK GEYFVGPEPE FFILKNENGK 150
    WVPGDDAGYF ELEPLDEGND LRRNIVFALE NLGFHVEASH HEVAPGQHEV 200
    DFKYDNAVKT ADSVITFKTT IKTLAKQSGV LATFMPKPFF GMNGSGMHCN 250
    QSIWLDGKPS FYDENNAHQL SDICLSYIGG ILEHTKALVS VTNPTVNSYK 300
    RLVPGYEAPV NIAWANSNRT SIIRVPAARG KGTRVEFRAP DPACNPYLAF 350
    TVMLAAGLDG VRRKLIAPEP VEKNIFAMSE AEKREANIDS VPSNLYDAIE 400
    ELRQDKVLKK ALGDHIFNKF IEIKTKEYDA YRTAVTDWEF NKYVRI 446
    Length:446
    Mass (Da):50,199
    Last modified:May 1, 1991 - v1
    Checksum:i95449E4DE8542690
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X53509 Genomic DNA. Translation: CAA37585.1.
    PIRiA43995.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X53509 Genomic DNA. Translation: CAA37585.1 .
    PIRi A43995.

    3D structure databases

    ProteinModelPortali P21154.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR004809. Gln_synth_I.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    TIGRFAMsi TIGR00653. GlnA. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence and expression of the glutamine synthetase structural gene, glnA, of the archaebacterium Methanococcus voltae."
      Possot O., Sibold L., Aubert J.-P.
      Res. Microbiol. 140:355-371(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS.

    Entry informationi

    Entry nameiGLNA_METVO
    AccessioniPrimary (citable) accession number: P21154
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 1991
    Last sequence update: May 1, 1991
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Lacks the tyrosine conserved in bacteria and other archaea, involved in feedback inhibition.Curated

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3