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P21154

- GLNA_METVO

UniProt

P21154 - GLNA_METVO

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Protein
Glutamine synthetase
Gene
glnA
Organism
Methanococcus voltae
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
OrganismiMethanococcus voltae
Taxonomic identifieri2188 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 446446Glutamine synthetase
PRO_0000153207Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP21154.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
TIGRFAMsiTIGR00653. GlnA. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P21154-1 [UniParc]FASTAAdd to Basket

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MTSLEMALEY IKINNVKFLR FQFVDIHGEP KNIAYPVKLG TADGEEELMG    50
VLENGLFFDG SSIEGFVEIE DSDMVLKPDL STLSVLPWRP SEKSVARIIC 100
DVYRKNGKPF EGDPRGCLKR VLAEFKEEFK GEYFVGPEPE FFILKNENGK 150
WVPGDDAGYF ELEPLDEGND LRRNIVFALE NLGFHVEASH HEVAPGQHEV 200
DFKYDNAVKT ADSVITFKTT IKTLAKQSGV LATFMPKPFF GMNGSGMHCN 250
QSIWLDGKPS FYDENNAHQL SDICLSYIGG ILEHTKALVS VTNPTVNSYK 300
RLVPGYEAPV NIAWANSNRT SIIRVPAARG KGTRVEFRAP DPACNPYLAF 350
TVMLAAGLDG VRRKLIAPEP VEKNIFAMSE AEKREANIDS VPSNLYDAIE 400
ELRQDKVLKK ALGDHIFNKF IEIKTKEYDA YRTAVTDWEF NKYVRI 446
Length:446
Mass (Da):50,199
Last modified:May 1, 1991 - v1
Checksum:i95449E4DE8542690
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X53509 Genomic DNA. Translation: CAA37585.1.
PIRiA43995.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X53509 Genomic DNA. Translation: CAA37585.1 .
PIRi A43995.

3D structure databases

ProteinModelPortali P21154.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
TIGRFAMsi TIGR00653. GlnA. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence and expression of the glutamine synthetase structural gene, glnA, of the archaebacterium Methanococcus voltae."
    Possot O., Sibold L., Aubert J.-P.
    Res. Microbiol. 140:355-371(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS.

Entry informationi

Entry nameiGLNA_METVO
AccessioniPrimary (citable) accession number: P21154
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 1991
Last sequence update: May 1, 1991
Last modified: October 16, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Lacks the tyrosine conserved in bacteria and other archaea, involved in feedback inhibition.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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