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Protein

P3 protein

Gene

Slc10a3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions.

GO - Molecular functioni

GO - Biological processi

  • response to organic substance Source: MGI
  • response to retinoic acid Source: MGI

Keywordsi

Biological processSymport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
P3 protein
Alternative name(s):
Solute carrier family 10 member 3
Gene namesi
Name:Slc10a3
Synonyms:P3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:95048 Slc10a3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21
Transmembranei249 – 269HelicalSequence analysisAdd BLAST21
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Transmembranei356 – 376HelicalSequence analysisAdd BLAST21
Transmembranei381 – 401HelicalSequence analysisAdd BLAST21
Transmembranei413 – 433HelicalSequence analysisAdd BLAST21
Transmembranei446 – 466HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000523441 – 473P3 proteinAdd BLAST473

Proteomic databases

PaxDbiP21129
PRIDEiP21129

PTM databases

PhosphoSitePlusiP21129

Expressioni

Gene expression databases

BgeeiENSMUSG00000032806
ExpressionAtlasiP21129 baseline and differential
GenevisibleiP21129 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045150

Structurei

3D structure databases

ProteinModelPortaliP21129
SMRiP21129
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2718 Eukaryota
COG0385 LUCA
GeneTreeiENSGT00550000074505
HOGENOMiHOG000037944
HOVERGENiHBG002872
InParanoidiP21129
KOiK14343
OMAiYASQAPF
OrthoDBiEOG091G0BJW
PhylomeDBiP21129
TreeFamiTF315811

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR002657 BilAc:Na_symport/Acr3
IPR004710 Bilac:Na_transpt
IPR038770 Na+/solute_symporter_sf
IPR030210 SLC10A3
PANTHERiPTHR10361 PTHR10361, 1 hit
PTHR10361:SF3 PTHR10361:SF3, 1 hit
PfamiView protein in Pfam
PF01758 SBF, 1 hit

Sequencei

Sequence statusi: Complete.

P21129-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVKKSRGSS QQLPGLGGQG GCTGFVGMLG TALLFISLPW GAQVMASANI
60 70 80 90 100
STALGHTSGH YLSIGDGSVT EFDFPEKSEG IIVISSQYTG QTNGTGPSPI
110 120 130 140 150
LKVISLDTEV LTIKNVSAIT WSSGGGFVVG IHSGLAGLAP LHLQLMDFYE
160 170 180 190 200
APPLLIEERR DFCIRVSPAE DLPSALNTNL GHFSENPILY LLLPLIFVNK
210 220 230 240 250
CSFGCKVELE VLKELLQSPQ PMLLGLLGQF LVMPFYAFLM AKVFMLPKAL
260 270 280 290 300
ALGLIITCSS PGGGGSYLFS LLLGGDVTLA ISMTFISTVA ATGFLPLSSA
310 320 330 340 350
IYSYLLSIHE TLHVPISKIL GTLLFIAIPI AAGVVIKSKL PKFSELLLQV
360 370 380 390 400
IKPFSFILLL GGLFLAYHMG VFILVGVRLP IVLVGFTVPL VGLLVGYSLA
410 420 430 440 450
ICLKLPVAQR RTVSIEVGVQ NSLLALAMLQ LSLRRLQADY ASQAPFIVAL
460 470
SGTSEMLALV IGQFIYSILF PVP
Length:473
Mass (Da):50,255
Last modified:August 30, 2005 - v2
Checksum:i9A2AD0A005DD1805
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK041958 mRNA Translation: BAC31110.1
BC023050 mRNA Translation: AAH23050.1
BC027440 mRNA Translation: AAH27440.1
J04761 Genomic DNA Translation: AAA40519.1
CCDSiCCDS30231.1
PIRiI54222
RefSeqiNP_001243033.1, NM_001256104.1
NP_663381.1, NM_145406.2
UniGeneiMm.19931

Genome annotation databases

EnsembliENSMUST00000037967; ENSMUSP00000045150; ENSMUSG00000032806
ENSMUST00000073067; ENSMUSP00000072818; ENSMUSG00000032806
ENSMUST00000114146; ENSMUSP00000109783; ENSMUSG00000032806
GeneIDi214601
KEGGimmu:214601
UCSCiuc009tou.2 mouse

Similar proteinsi

Entry informationi

Entry nameiP3_MOUSE
AccessioniPrimary (citable) accession number: P21129
Secondary accession number(s): Q8QZR2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: August 30, 2005
Last modified: May 23, 2018
This is version 129 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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