Reviewed,
UniProtKB/Swiss-Prot P21079 (PAP1_VACCC)
Last modified
June 16, 2009.
Version 48.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Poly(A) polymerase catalytic subunit EC=2.7.7.19 Alternative name(s): Poly(A) polymerase large subunit Short name=PAP-L VP55 | ||||
| Gene names |
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| Organism | Vaccinia virus (strain Copenhagen) (VACV) [Complete proteome] | ||||
| Taxonomic identifier | 10249 [NCBI] | ||||
| Taxonomic lineage | Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus | ||||
| Virus host | Homo sapiens (Human) [TaxID: 9606] |
Protein attributes
| Sequence length | 479 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Polymerase that creates the 3'-poly(A) tail of mRNA's. |
| Catalytic activity | ATP + RNA(n) = diphosphate + RNA(n+1). |
| Subunit structure | Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit. |
| Sequence similarities | Belongs to the poxviridae poly(A) polymerase catalytic subunit family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription mRNA processing |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW transcriptionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW polynucleotide adenylyltransferase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The complete DNA sequence of vaccinia virus." Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P., Paoletti E. Virology 179:247-266(1990) [PubMed: 2219722] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [2] | "Appendix to 'The complete DNA sequence of vaccinia virus'." Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P., Paoletti E. Virology 179:517-563(1990) Cited for: COMPLETE GENOME. |
Cross-references
Sequence databases | |
|---|---|
| M35027 Genomic DNA. Translation: AAA48038.1. | |
| PIR | E42508. |
3D structure databases | |
| SMR | P21079. Positions 12-479. |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR004976. PolyA_pol_cat_poxviral. [Graphical view] |
| Pfam | PF03296. Pox_polyA_pol. 1 hit. [Graphical view] |
| PIRSF | PIRSF015693. VAC-48L_nuct. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PAP1_VACCC | ||||||||
| Accession | Primary (citable) accession number: P21079 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Virus (Virus annotation project) | ||||||||

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