ID   A34_VACCC               Reviewed;         168 AA.
AC   P21057;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   19-OCT-2011, entry version 58.
DE   RecName: Full=Protein A34;
GN   ORFNames=A34R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae;
OC   Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=91021027; PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Required for the envelopment of intracellular viral
CC       particles and egress of enveloped virions from the infected cell
CC       (By similarity).
CC   -!- SUBUNIT: Interacts with proteins A36 AND B5 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Virion membrane; Single-pass type II
CC       membrane protein (Potential). Note=Present in the enveloped virion
CC       (EV) membrane (By similarity).
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A34 protein family.
CC   -!- SIMILARITY: Contains 1 C-type lectin domain.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; M35027; AAA48161.1; -; Genomic_DNA.
DR   PIR; I42520; I42520.
DR   ProteinModelPortal; P21057; -.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   InterPro; IPR001304; C-type_lectin.
DR   InterPro; IPR016186; C-type_lectin-like.
DR   InterPro; IPR016187; C-type_lectin_fold.
DR   Gene3D; G3DSA:3.10.100.10; C-type_lectin-like; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; C-type_lectin_fold; 1.
DR   PROSITE; PS00615; C_TYPE_LECTIN_1; FALSE_NEG.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Disulfide bond; Membrane; Signal-anchor;
KW   Transmembrane; Transmembrane helix; Virion.
FT   CHAIN         1    168       Protein A34.
FT                                /FTId=PRO_0000099319.
FT   TOPO_DOM      1     14       Cytoplasmic.
FT   TRANSMEM     15     37       Helical; (Potential).
FT   TOPO_DOM     38    168       Extracellular (Potential).
FT   DOMAIN       54    163       C-type lectin.
FT   DISULFID     75    162       By similarity.
FT   DISULFID    141    154       By similarity.
SQ   SEQUENCE   168 AA;  19529 MW;  32CCB4B0614D2255 CRC64;
     MKSLNRQTVS MFKKLSVPAA IMMILSTIIS GIGTFLHYKE ELMPSACANG WIQYDKHCYL
     DTNIKMSTDN AVYQCRKLRA RLPRPDTRHL RVLFSIFYKD YWVSLKKTNN KWLDINNDKD
     IDISKLTNFK QLNSTTDAEA CYIYKSGKLV KTVCKSTQSV LCVKKFYK
//