Reviewed, UniProtKB/Swiss-Prot P21057 (VA34_VACCC)

Names and origin

Protein names

Recommended name:
Protein A34

Gene names

ORF Names:

A34R

Organism

Vaccinia virus (strain Copenhagen) (VACV) [Complete proteome]

Taxonomic identifier

10249 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus › Vaccinia virus

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Function	Required for the envelopment of intracellular naked virus and egress of extracellular enveloped virus from the cell.
Subcellular location	Membrane; Single-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 168	168	Protein A34		PRO_0000099319
Regions
	Transmembrane	1 – 20	20	Signal-anchor Potential
	Topological domain	21 – 168	148	Extracellular Potential

Sequences

	Sequence		Length	Mass (Da)
	P21057-1 [UniParc]. Last modified February 1, 1991. Version 1. Checksum: 32CCB4B0614D2255	FASTA	168	19,529
	10 20 30 40 50 60 MKSLNRQTVS MFKKLSVPAA IMMILSTIIS GIGTFLHYKE ELMPSACANG WIQYDKHCYL 70 80 90 100 110 120 DTNIKMSTDN AVYQCRKLRA RLPRPDTRHL RVLFSIFYKD YWVSLKKTNN KWLDINNDKD 130 140 150 160 IDISKLTNFK QLNSTTDAEA CYIYKSGKLV KTVCKSTQSV LCVKKFYK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete DNA sequence of vaccinia virus." Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P., Paoletti E. Virology 179:247-266(1990) [PubMed: 2219722] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Appendix to 'The complete DNA sequence of vaccinia virus'." Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P., Paoletti E. Virology 179:517-563(1990) Cited for: COMPLETE GENOME.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M35027 Genomic DNA. Translation: AAA48161.1.
PIR	I42520.
3D structure databases
SMR	P21057. Positions 45-165.
ModBase	Search...
Family and domain databases
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR016187. C-type_lectin_fold. [Graphical view]
Gene3D	G3DSA:3.10.100.10. C-type_lectin-like. 1 hit.
SMART	SM00034. CLECT. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit.
PROSITE	PS50041. C_TYPE_LECTIN_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VA34_VACCC

Accession

Primary (citable) accession number: P21057

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1991
Last sequence update:	February 1, 1991
Last modified:	March 2, 2010
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Virus (Virus annotation project)