Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P20971

- PGK_METFV

UniProt

P20971 - PGK_METFV

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Feb 1991)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateBy similarity
    Binding sitei119 – 1191SubstrateBy similarity
    Binding sitei159 – 1591SubstrateBy similarity
    Binding sitei332 – 3321ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi358 – 3614ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMFER523846:GC24-165-MONOMER.
    SABIO-RKP20971.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:pgk
    Ordered Locus Names:Mfer_0156
    OrganismiMethanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)
    Taxonomic identifieri523846 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanothermaceaeMethanothermus
    ProteomesiUP000002315: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 410410Phosphoglycerate kinasePRO_0000146057Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.

    Structurei

    3D structure databases

    ProteinModelPortaliP20971.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni22 – 243Substrate bindingBy similarity
    Regioni62 – 654Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Phylogenomic databases

    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiTEYHANT.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P20971-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFKFYTMDDF DYSGSRVLVR VDINSPVDPH TGRILDDTRM RLHSKTLKEL    50
    VDENAKVAIL AHQSRPGKRD FTTMEEHSKV LSNILDMPVT YVEDIFGCAA 100
    RESIRNMENG DIILLENVRF YSEEVLKRDP KVQAETHLVR KLSSVVDYYI 150
    NDAFAAAHRS QPSLVGFPLK LPSAAGRLME REVKTLYKII KNVEKPCVYI 200
    LGGVKIDDSI MIMKNILKNG SADYILTSGL VANVFLEASG IDIKEKNRKI 250
    LYRKNYKKFI KMAKKLKDKY GEKILTPVDV AINKNGKRID VPIDDIPNFP 300
    IYDIGMETIK IYAEKIREAK TIFANGPAGV FEEQQFSIGT EDLLNAIASS 350
    NAFSVIAGGH LAAAAEKMGI SNKINHISSG GGACIAFLSG EELPAIKVLE 400
    EARKRSDKYI 410
    Length:410
    Mass (Da):45,871
    Last modified:February 1, 1991 - v1
    Checksum:i6AA54EB65C292EFA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M55529 Genomic DNA. Translation: AAA72936.1.
    CP002278 Genomic DNA. Translation: ADP76959.1.
    PIRiPN0008.
    RefSeqiWP_013413237.1. NC_014658.1.
    YP_004003721.1. NC_014658.1.

    Genome annotation databases

    EnsemblBacteriaiADP76959; ADP76959; Mfer_0156.
    GeneIDi9961867.
    KEGGimfv:Mfer_0156.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M55529 Genomic DNA. Translation: AAA72936.1 .
    CP002278 Genomic DNA. Translation: ADP76959.1 .
    PIRi PN0008.
    RefSeqi WP_013413237.1. NC_014658.1.
    YP_004003721.1. NC_014658.1.

    3D structure databases

    ProteinModelPortali P20971.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADP76959 ; ADP76959 ; Mfer_0156 .
    GeneIDi 9961867.
    KEGGi mfv:Mfer_0156.

    Phylogenomic databases

    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi TEYHANT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci MFER523846:GC24-165-MONOMER.
    SABIO-RK P20971.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and sequencing the gene encoding 3-phosphoglycerate kinase from mesophilic Methanobacterium bryantii and thermophilic Methanothermus fervidus."
      Fabry S., Heppner P., Dietmaier W., Hensel R.
      Gene 91:19-25(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 43054 / DSM 2088 / JCM 10308 / V24 S.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43054 / DSM 2088 / JCM 10308 / V24 S.

    Entry informationi

    Entry nameiPGK_METFV
    AccessioniPrimary (citable) accession number: P20971
    Secondary accession number(s): E3GXC7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3