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P20847 (GUN1_BUTFI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 1

EC=3.2.1.4
Alternative name(s):
Cellulase 1
Endo-1,4-beta-glucanase 1
Gene names
Name:end1
OrganismButyrivibrio fibrisolvens
Taxonomic identifier831 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeButyrivibrio

Protein attributes

Sequence length547 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Contains 1 CBM2 (carbohydrate binding type-2) domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 547547Endoglucanase 1
PRO_0000184046

Regions

Domain448 – 547100CBM2

Sites

Active site1891Proton donor By similarity
Active site3211Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P20847 [UniParc].

Last modified February 1, 1991. Version 1.
Checksum: C62EE40E6442ECF9

FASTA54761,078
        10         20         30         40         50         60 
MHKSKCIKRV FTFLLALFVF VMAIPATKVS AAGGTDRSAT QVVSDMRVGW NIGNSLDSFG 

        70         80         90        100        110        120 
QSYNFPYTSL NETYWGNPAT TKALIDEVAK AGFNTIRIPV SWGQYTTGSD YQIPDFVMNR 

       130        140        150        160        170        180 
VKEVVDYCIV NDMYVILNSH HDINSDYCFY VPNNANKDRS EKYFKSIWTQ IAKEFKNYDY 

       190        200        210        220        230        240 
HLVFETMNEP RLVGHGEEWW FPRNNPSNDI REAVACINDY NQVALDAIRA TGGNNATRCV 

       250        260        270        280        290        300 
MVPGYDASIE GCMTDGFKMP NDTASGRLIL SVHAYIPYYF ALASDTYVTR FDDNLKYDID 

       310        320        330        340        350        360 
SFFNDLNSKF LSRNIPVVVG ETSATNRNNT AERVKWADYY WGRAARYSNV AMVLWDNNIY 

       370        380        390        400        410        420 
QNNSAGSDGE CHMYIDRNSL QWKDPEIIST IMKHVDGTPA TINGKEIPST EQPDPTPVDP 

       430        440        450        460        470        480 
DPTPVDPDPT PVDPDPTPVD PDPQPVDPTP VSGALKAEYT INNWGSGYQV LIKVKNDSAS 

       490        500        510        520        530        540 
RVDGWTLKIS KSEVKIDSSW CVNIAEEGGY YVITPMSWNS SLEPSASVDF GIQGSGSIGT 


SVNISVQ 

« Hide

References

[1]"Cloning and sequencing of an endoglucanase (end1) gene from Butyrivibrio fibrisolvens H17c."
Berger E., Jones W.A., Jones D.T., Woods D.R.
Mol. Gen. Genet. 219:193-198(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: H17C.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X17538 Genomic DNA. Translation: CAA35574.1.
PIRJQ0356.

3D structure databases

ProteinModelPortalP20847.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM2. Carbohydrate-Binding Module Family 2.
GH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.40.290. 1 hit.
3.20.20.80. 1 hit.
InterProIPR008965. Carb-bd_dom.
IPR012291. CBD_carb-bd_dom.
IPR018366. CBM2_CS.
IPR001919. Cellulose-bd_dom_fam2_bac.
IPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00553. CBM_2. 1 hit.
PF00150. Cellulase. 1 hit.
[Graphical view]
SMARTSM00637. CBD_II. 1 hit.
[Graphical view]
SUPFAMSSF49384. SSF49384. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEPS51173. CBM2. 1 hit.
PS00561. CBM2_A. 1 hit.
PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN1_BUTFI
AccessionPrimary (citable) accession number: P20847
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: October 16, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries