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P20805

- GLNA2_FRAAL

UniProt

P20805 - GLNA2_FRAAL

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Protein

Glutamine synthetase 2

Gene

glnII

Organism
Frankia alni
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Assimilates ammonia during nitrogen limitation. May also have a role in plant symbioses.

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: UniProtKB-KW
  3. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Nitrogen fixation, Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase 2 (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase II
Glutamine synthetase II
Short name:
GSII
Gene namesi
Name:glnII
OrganismiFrankia alni
Taxonomic identifieri1859 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 352352Glutamine synthetase 2PRO_0000153222Add
BLAST

Expressioni

Inductioni

By nitrogen starvation.

Interactioni

Subunit structurei

Homooctamer.

Structurei

3D structure databases

ProteinModelPortaliP20805.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P20805-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYQAEYIWI DGTEPEPLMR SKTRIIKDGK EPEIWGFDGS STNQAPGSNS
60 70 80 90 100
DCVLRPVFET PDPIRGGDNR LVLCEVQLTD FTPPTNTRAA ALGVAERYAD
110 120 130 140 150
MSPMFGIEQE YTFFKDGRPY GWPEVGYPAP QGPYYCGVGG SKMPGRQIVE
160 170 180 190 200
RHTQACLDAG LAIEGTNAEV MMGQWEFQIG VLPAPAIGDQ IWLGRWLLHR
210 220 230 240 250
IAEDYGVEVS FAAKPIPGDW NGAGAHTNFS TKQTMEGWDA IVTCCEALGT
260 270 280 290 300
RVTEHVTHYG KGIEDRLTGK HETAPWNKYS WGASDRGASV RIPWAVEKAK
310 320 330 340 350
KGWLEDRRPN ANMDPYLVTA LMIDTCCSAL AGDKPTLFVP SQTTPAPAEA

SV
Length:352
Mass (Da):38,666
Last modified:February 1, 1991 - v1
Checksum:i2BFCC8B8A87C3340
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M58415 Genomic DNA. Translation: AAA62803.1.
L10632 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M58415 Genomic DNA. Translation: AAA62803.1 .
L10632 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali P20805.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
PROSITEi PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning, sequencing, and expression of the glutamine synthetase II (glnII) gene from the actinomycete root nodule symbiont Frankia sp. strain CpI1."
    Rochefort D.A., Benson D.R.
    J. Bacteriol. 172:5335-5342(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: CpI1.
  2. "Close linkage of genes encoding glutamine synthetases I and II in Frankia alni CpI1."
    Hosted T.J., Rochefort D.A., Benson D.R.
    J. Bacteriol. 175:3679-3684(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-9.
    Strain: CpI1.

Entry informationi

Entry nameiGLNA2_FRAAL
AccessioniPrimary (citable) accession number: P20805
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Two forms of glutamine synthetase (GSI and GSII) can be found in this nitrogen fixing bacteria, GSI is a typical prokaryotic glutamine synthetase whereas GSII is similar to the eukaryotic enzyme.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3