Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Enterotoxin type D

Gene

entD

Organism
Staphylococcus aureus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi212Zinc1
Metal bindingi250Zinc1
Metal bindingi252Zinc1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEnterotoxin, Superantigen, Toxin
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Enterotoxin type D
Alternative name(s):
SED
Gene namesi
Name:entD
OrganismiStaphylococcus aureus
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Protein family/group databases

Allergomei2142. Sta a SED.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Add BLAST25
ChainiPRO_000003561226 – 258Enterotoxin type DAdd BLAST233

Interactioni

Subunit structurei

Homodimer; zinc-dependent.

Structurei

3D structure databases

ProteinModelPortaliP20723.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008992. Enterotoxin.
IPR006126. Staph/Strept_toxin_CS.
IPR006173. Staph_tox_OB.
IPR016091. SuperAg_toxin_C.
IPR013307. Superantigen_bac.
IPR006123. Toxin_b-grasp_Staph/Strep.
IPR006177. Toxin_bac.
PfamiView protein in Pfam
PF02876. Stap_Strp_tox_C. 1 hit.
PF01123. Stap_Strp_toxin. 1 hit.
PRINTSiPR00279. BACTRLTOXIN.
PR01898. SAGSUPRFAMLY.
SUPFAMiSSF50203. SSF50203. 1 hit.
SSF54334. SSF54334. 1 hit.
PROSITEiView protein in PROSITE
PS00277. STAPH_STREP_TOXIN_1. 1 hit.
PS00278. STAPH_STREP_TOXIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P20723-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFNILIAL LFFTSLVISP LNVKANENID SVKEKELHKK SELSSTALNN
60 70 80 90 100
MKHSYADKNP IIGENKSTGD QFLENTLLYK KFFTDLINFE DLLINFNSKE
110 120 130 140 150
MAQHFKSKNV DVYPIRYSIN CYGGEIDRTA CTYGGVTPHE GNKLKERKKI
160 170 180 190 200
PINLWINGVQ KEVSLDKVQT DKKNVTVQEL DAQARRYLQK DLKLYNNDTL
210 220 230 240 250
GGKIQRGKIE FDSSDGSKVS YDLFDVKGDF PEKQLRIYSD NKTLSTEHLH

IDIYLYEK
Length:258
Mass (Da):29,746
Last modified:February 1, 1991 - v1
Checksum:i4F7C6A28D42597FD
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti114P → A in strain: ATCC 23235. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M28521 Genomic DNA. Translation: AAB06195.1.
PIRiA33953.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiETXD_STAAU
AccessioniPrimary (citable) accession number: P20723
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: April 12, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families