##gff-version 3
P20712	UniProtKB	Chain	1	583	.	.	.	ID=PRO_0000186348;Note=Bifunctional dihydrofolate reductase-thymidylate synthase	
P20712	UniProtKB	Domain	9	229	.	.	.	Note=DHFR	
P20712	UniProtKB	Region	298	583	.	.	.	Note=Thymidylate synthase	
P20712	UniProtKB	Active site	465	465	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	36	42	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	51	51	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	104	106	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	125	128	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	165	165	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	166	173	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	171	171	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	186	186	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	320	320	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	466	466	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	484	488	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	496	496	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Binding site	526	528	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P20712	UniProtKB	Natural variant	106	106	.	.	.	Note=In pyrimethamine resistance. S->I	
P20712	UniProtKB	Sequence conflict	27	27	.	.	.	Note=G->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P20712	UniProtKB	Sequence conflict	156	156	.	.	.	Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P20712	UniProtKB	Sequence conflict	164	164	.	.	.	Note=I->V;Ontology_term=ECO:0000305;evidence=ECO:0000305