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Reviewed, UniProtKB/Swiss-Prot P20655 (RIPS_MOMCO)

Last modified June 16, 2009. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ribosome-inactivating protein momorcochin-S
    EC=3.2.2.22
Alternative name(s):
    rRNA N-glycosidase
OrganismMomordica cochinchinensis (Spiny bitter cucumber)
Taxonomic identifier3674 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids ICucurbitalesCucurbitaceaeMomordica

Protein attributes

Sequence length30 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Inactivates eukaryotic 60S ribosomal subunits.

Catalytic activity

Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.

Post-translational modification

Glycosylated. Ref.1

Sequence similarities

Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›30›30Ribosome-inactivating protein momorcochin-S
PRO_0000221410

Experimental info

Non-terminal residue301

Sequences

Sequence LengthMass (Da)Tools
P20655-1 [UniParc].

Last modified February 1, 1991. Version 1.
Checksum: 5B93CE73B9E3E221

FASTA303,323
        10         20         30 
DVTFSLLGAN TKSYAAFITN FRKDVASEKK 

« Hide

References

[1]"Purification and properties of a new ribosome-inactivating protein with RNA N-glycosidase activity suitable for immunotoxin preparation from the seeds of Momordica cochinchinensis."
Bolognesi A., Barbieri L., Carnicelli D., Abbondanza A., Cenini P., Falasca A.I., Dinota A., Stirpe F.
Biochim. Biophys. Acta 993:287-292(1989) [PubMed: 2597699] [Abstract]
Cited for: PROTEIN SEQUENCE, GLYCOSYLATION.
Tissue: Seed.

Cross-references

Sequence databases

PIRS07065.

3D structure databases

ModBaseSearch...

Enzyme and pathway databases

BRENDA3.2.2.22. 273564.

Family and domain databases

InterProIPR001574. Ribosome_inactivat_prot.
IPR017988. Ribosome_inactivat_prot_CS.
[Graphical view]
PfamPF00161. RIP. 1 hit.
[Graphical view]
PROSITEPS00275. SHIGA_RICIN. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRIPS_MOMCO
AccessionPrimary (citable) accession number: P20655
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: June 16, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents