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P20609

- COXE_DICDI

UniProt

P20609 - COXE_DICDI

Protein

Cytochrome c oxidase subunit 7e

Gene

cxgE

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 7e (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide VIIe
    Gene namesi
    Name:cxgE
    Synonyms:cox7e
    ORF Names:DDB_G0277837
    OrganismiDictyostelium discoideum (Slime mold)
    Taxonomic identifieri44689 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
    ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

    Organism-specific databases

    dictyBaseiDDB_G0277837. cxgE.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 5352Cytochrome c oxidase subunit 7ePRO_0000183908Add
    BLAST

    Proteomic databases

    PRIDEiP20609.

    Expressioni

    Developmental stagei

    When cells enter the stationary phase of growth, during the vegetative state, subunit VIIe is replaced by VIIs. The switching depends on the oxygen tension.

    Interactioni

    Subunit structurei

    Slime mold cytochrome c oxidase consists of at least seven different polypeptides species, subunits I, II, III, IV, V, VI, and VIIe/s in order of MW.

    Family & Domainsi

    Phylogenomic databases

    OMAiIHITMAR.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P20609-1 [UniParc]FASTAAdd to Basket

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    MSHALPALIK MHITKDIGYG LLLGIIPGVW FKYQIGQSIQ KREDFYAAYD   50
    KRN 53
    Length:53
    Mass (Da):6,110
    Last modified:January 23, 2007 - v3
    Checksum:i1A365C9587D9CE76
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X55673 mRNA. Translation: CAA39208.1.
    X99344 Genomic DNA. Translation: CAA67724.1.
    AAFI02000023 Genomic DNA. Translation: EAL68091.1.
    PIRiS13105.
    RefSeqiXP_642042.1. XM_636950.1.

    Genome annotation databases

    EnsemblProtistsiDDB0216179; DDB0216179; DDB_G0277837.
    GeneIDi8621254.
    KEGGiddi:DDB_G0277837.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X55673 mRNA. Translation: CAA39208.1 .
    X99344 Genomic DNA. Translation: CAA67724.1 .
    AAFI02000023 Genomic DNA. Translation: EAL68091.1 .
    PIRi S13105.
    RefSeqi XP_642042.1. XM_636950.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P20609.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi DDB0216179 ; DDB0216179 ; DDB_G0277837 .
    GeneIDi 8621254.
    KEGGi ddi:DDB_G0277837.

    Organism-specific databases

    dictyBasei DDB_G0277837. cxgE.

    Phylogenomic databases

    OMAi IHITMAR.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the cDNA encoding subunit VIIe of cytochrome c oxidase from the slime mold Dictyostelium discoideum."
      Rizzuto R., Sandona D., Capaldi R.A., Bisson R.
      Nucleic Acids Res. 18:6711-6711(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: AX3.
    2. "Subunit change in cytochrome c oxidase: identification of the oxygen switch in Dictyostelium."
      Bisson R., Vettore S., Aratri E., Sandona D.
      EMBO J. 16:739-749(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: AX3.
    3. "The genome of the social amoeba Dictyostelium discoideum."
      Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
      , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
      Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AX4.
    4. "The two oxygen-regulated subunits of cytochrome c oxidase in Dictyostelium discoideum derive from a common ancestor."
      Capaldi R.A., Zhang Y.-Z., Rizzuto R., Sandona D., Schiavo G., Bisson R.
      FEBS Lett. 261:158-160(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-35.

    Entry informationi

    Entry nameiCOXE_DICDI
    AccessioniPrimary (citable) accession number: P20609
    Secondary accession number(s): Q54Z10
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 76 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Dictyostelium discoideum
      Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

    External Data

    Dasty 3