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P20609

- COXE_DICDI

UniProt

P20609 - COXE_DICDI

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Protein

Cytochrome c oxidase subunit 7e

Gene
cxgE, cox7e, DDB_G0277837
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7e (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide VIIe
Gene namesi
Name:cxgE
Synonyms:cox7e
ORF Names:DDB_G0277837
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 3, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0277837. cxgE.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 5352Cytochrome c oxidase subunit 7ePRO_0000183908Add
BLAST

Proteomic databases

PRIDEiP20609.

Expressioni

Developmental stagei

When cells enter the stationary phase of growth, during the vegetative state, subunit VIIe is replaced by VIIs. The switching depends on the oxygen tension.

Interactioni

Subunit structurei

Slime mold cytochrome c oxidase consists of at least seven different polypeptides species, subunits I, II, III, IV, V, VI, and VIIe/s in order of MW.

Family & Domainsi

Phylogenomic databases

OMAiIHITMAR.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P20609-1 [UniParc]FASTAAdd to Basket

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MSHALPALIK MHITKDIGYG LLLGIIPGVW FKYQIGQSIQ KREDFYAAYD   50
KRN 53
Length:53
Mass (Da):6,110
Last modified:January 23, 2007 - v3
Checksum:i1A365C9587D9CE76
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X55673 mRNA. Translation: CAA39208.1.
X99344 Genomic DNA. Translation: CAA67724.1.
AAFI02000023 Genomic DNA. Translation: EAL68091.1.
PIRiS13105.
RefSeqiXP_642042.1. XM_636950.1.

Genome annotation databases

EnsemblProtistsiDDB0216179; DDB0216179; DDB_G0277837.
GeneIDi8621254.
KEGGiddi:DDB_G0277837.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X55673 mRNA. Translation: CAA39208.1 .
X99344 Genomic DNA. Translation: CAA67724.1 .
AAFI02000023 Genomic DNA. Translation: EAL68091.1 .
PIRi S13105.
RefSeqi XP_642042.1. XM_636950.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P20609.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0216179 ; DDB0216179 ; DDB_G0277837 .
GeneIDi 8621254.
KEGGi ddi:DDB_G0277837.

Organism-specific databases

dictyBasei DDB_G0277837. cxgE.

Phylogenomic databases

OMAi IHITMAR.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the cDNA encoding subunit VIIe of cytochrome c oxidase from the slime mold Dictyostelium discoideum."
    Rizzuto R., Sandona D., Capaldi R.A., Bisson R.
    Nucleic Acids Res. 18:6711-6711(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: AX3.
  2. "Subunit change in cytochrome c oxidase: identification of the oxygen switch in Dictyostelium."
    Bisson R., Vettore S., Aratri E., Sandona D.
    EMBO J. 16:739-749(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: AX3.
  3. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.
  4. "The two oxygen-regulated subunits of cytochrome c oxidase in Dictyostelium discoideum derive from a common ancestor."
    Capaldi R.A., Zhang Y.-Z., Rizzuto R., Sandona D., Schiavo G., Bisson R.
    FEBS Lett. 261:158-160(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-35.

Entry informationi

Entry nameiCOXE_DICDI
AccessioniPrimary (citable) accession number: P20609
Secondary accession number(s): Q54Z10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

External Data

Dasty 3