Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphate-repressible acid phosphatase

Gene

pacA

Organism
Aspergillus niger
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
  2. metal ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate-repressible acid phosphatase (EC:3.1.3.2)
Alternative name(s):
Acid phosphatase PII
Gene namesi
Name:pacA
Synonyms:aphA
OrganismiAspergillus niger
Taxonomic identifieri5061 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 436416Phosphate-repressible acid phosphatasePRO_0000023980Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi227 – 2271N-linked (GlcNAc...)Sequence Analysis
Glycosylationi283 – 2831N-linked (GlcNAc...)Sequence Analysis
Glycosylationi304 – 3041N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliP20584.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
[Graphical view]
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P20584-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGTAASALL IALSATAAQA RPVVDERFPY TGPAVPIGDW VDPTINGNGK
60 70 80 90 100
GFPRLVEPPA VKPATANPRN NVNVISLSYI PKGMHIHYQT PFGLGQLPAV
110 120 130 140 150
RWGKDPRNLK QHGAGLLSHF QDWSSGRSPG IVQRRRAERH GLHQRSRNTQ
160 170 180 190 200
AAGQGCPMRE LPFAWPTEVT ISYADELGII LVPTTGRSAT TAPVLLFRVA
210 220 230 240 250
YSGRVQEALA RGEIPDQGEV VANRRRNFTA YQHPFRMPGP ETGGVGNFWY
260 270 280 290 300
SFDYGLAHFV SIDGETDFAN SPEWNFAEDV TGNETLPSEA ETFITDSGPF
310 320 330 340 350
GNVNGSVHET KSYEQWHLAE AGSGEGRPQQ DPVGLRHEPP PYVQFRLFLY
360 370 380 390 400
QLHVREAFEG LLLSMAWMLT SLGDVCPFFK LVHHPLTLSS ATSTGTSSLS
410 420 430
SRATAPSILP PCEQQHLLCP QRQVHHPHHQ RHGRQH
Length:436
Mass (Da):47,995
Last modified:January 31, 1991 - v1
Checksum:i852E98ADD2859E15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23540 Genomic DNA. Translation: AAA32700.1.
PIRiJT0386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23540 Genomic DNA. Translation: AAA32700.1.
PIRiJT0386.

3D structure databases

ProteinModelPortaliP20584.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR029052. Metallo-depent_PP-like.
IPR008963. Purple_acid_Pase-like_N.
[Graphical view]
SUPFAMiSSF49363. SSF49363. 1 hit.
SSF56300. SSF56300. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A phosphate-repressible acid phosphatase gene from Aspergillus niger: its cloning, sequencing and transcriptional analysis."
    Macrae W.D., Buxton F.P., Sibley S., Garven S., Gwynne D.I., Davies R.W., Arst H.N. Jr.
    Gene 71:339-348(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 46951.

Entry informationi

Entry nameiPPA1_ASPNG
AccessioniPrimary (citable) accession number: P20584
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 1991
Last sequence update: January 31, 1991
Last modified: March 31, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.