Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein I5

Gene

I5L

Organism
Vaccinia virus (strain Copenhagen) (VACV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Envelope protein.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein I5
Gene namesi
ORF Names:I5L
OrganismiVaccinia virus (strain Copenhagen) (VACV)
Taxonomic identifieri10249 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000008269 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 8IntravirionSequence analysis8
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Topological domaini30 – 47Virion surfaceSequence analysisAdd BLAST18
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 79IntravirionSequence analysisAdd BLAST11

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Viral envelope protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000995751 – 79Protein I5Add BLAST79

Expressioni

Inductioni

Expressed in the late phase of the viral replicative cycle.

Keywords - Developmental stagei

Late protein

Family & Domainsi

Sequence similaritiesi

Belongs to the Chordopoxvirinae I5 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090001P4.

Family and domain databases

InterProiView protein in InterPro
IPR006803. Poxvirus_I5.
PfamiView protein in Pfam
PF04713. Pox_I5. 1 hit.
PIRSFiPIRSF003768. VAC_I5L. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012198. Pox_I5. 1 hit.

Sequencei

Sequence statusi: Complete.

P20500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDAITVLTA IGITVLMLLM VISGAAMIVK ELNPNDIFTM QSLKFNRAVT
60 70
IFKYIGLFIY IPGTIILYAT YVKSLLMKS
Length:79
Mass (Da):8,762
Last modified:February 1, 1991 - v1
Checksum:i76F4826B7009DFAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA. Translation: AAA48061.1.
PIRiA42511.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiI5_VACCC
AccessioniPrimary (citable) accession number: P20500
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: March 15, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families