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Protein

DNA-directed RNA polymerases I, II, and III subunit RPABC1

Gene

RPB5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. RNA polymerase complexes are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.3 Publications

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • RNA polymerase I activity Source: UniProtKB

GO - Biological processi

  • ribosome biogenesis Source: UniProtKB-KW
  • termination of RNA polymerase III transcription Source: Reactome
  • transcription, RNA-templated Source: GOC
  • transcription elongation from RNA polymerase III promoter Source: Reactome
  • transcription from RNA polymerase III promoter Source: SGD
  • transcription from RNA polymerase II promoter Source: SGD
  • transcription from RNA polymerase I promoter Source: UniProtKB
  • tRNA transcription from RNA polymerase III promoter Source: SGD
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis, Transcription

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-29104-MONOMER.
ReactomeiR-SCE-113418. Formation of the Early Elongation Complex.
R-SCE-674695. RNA Polymerase II Pre-transcription Events.
R-SCE-6781823. Formation of TC-NER Pre-Incision Complex.
R-SCE-6782135. Dual incision in TC-NER.
R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes.
R-SCE-72086. mRNA Capping.
R-SCE-72165. mRNA Splicing - Minor Pathway.
R-SCE-73776. RNA Polymerase II Promoter Escape.
R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-SCE-73780. RNA Polymerase III Chain Elongation.
R-SCE-73980. RNA Polymerase III Transcription Termination.
R-SCE-749476. RNA Polymerase III Abortive And Retractive Initiation.
R-SCE-75953. RNA Polymerase II Transcription Initiation.
R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-SCE-76061. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
R-SCE-76066. RNA Polymerase III Transcription Initiation From Type 2 Promoter.
R-SCE-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.
R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Short name:
RNA polymerases I, II, and III subunit ABC1
Alternative name(s):
ABC27
DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide
Gene namesi
Name:RPB5
Synonyms:RPA7, RPC9
Ordered Locus Names:YBR154C
ORF Names:YBR1204
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:YBR154C.
SGDiS000000358. RPB5.

Subcellular locationi

GO - Cellular componenti

  • DNA-directed RNA polymerase I complex Source: UniProtKB
  • DNA-directed RNA polymerase II, core complex Source: SGD
  • DNA-directed RNA polymerase III complex Source: SGD
  • nucleoplasm Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

DNA-directed RNA polymerase, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215DNA-directed RNA polymerases I, II, and III subunit RPABC1PRO_0000146086Add
BLAST

Proteomic databases

MaxQBiP20434.

Interactioni

Subunit structurei

Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes. Component of the RNA polymerase I (Pol I) complex consisting of 14 subunits: RPA135, RPA190, RPC40, RPA14, RPB5, RPO26, RPA43, RPB8, RPA12, RPB10, RPC19, RPC10, RPA49 and RPA34. The complex is composed of a horseshoe-shaped core containing ten subunits (RPA135, RPA190, RPB5, RPO26, RPB8, RPB10, RPC10, RPA12, RPC19 and RPC40) where RPA135 and RPA190 form the DNA-binding cleft. Outside of the core, RPA14 and RPA43 form the stalk that mediates interactions with transcription initiation factors and newly synthesized RNA. Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits: RPO21, RPB2, RPB3, RPB4, RPB5, RPO26, RPB7, RPB8, RPB9, RPB10 and RPC10. Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.9 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
RPB2P085188EBI-15781,EBI-15767

Protein-protein interaction databases

BioGridi32853. 89 interactions.
DIPiDIP-71N.
IntActiP20434. 50 interactions.
MINTiMINT-530046.

Structurei

Secondary structure

1
215
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni3 – 53Combined sources
Helixi7 – 2519Combined sources
Helixi32 – 354Combined sources
Helixi39 – 468Combined sources
Beta strandi49 – 513Combined sources
Helixi55 – 573Combined sources
Beta strandi60 – 623Combined sources
Helixi66 – 716Combined sources
Beta strandi72 – 743Combined sources
Beta strandi78 – 825Combined sources
Beta strandi84 – 885Combined sources
Helixi90 – 10213Combined sources
Beta strandi106 – 11611Combined sources
Helixi118 – 1214Combined sources
Turni122 – 1254Combined sources
Beta strandi127 – 1293Combined sources
Beta strandi131 – 1366Combined sources
Helixi137 – 1404Combined sources
Helixi144 – 1463Combined sources
Beta strandi147 – 1493Combined sources
Beta strandi152 – 1554Combined sources
Helixi158 – 16710Combined sources
Helixi172 – 1743Combined sources
Beta strandi177 – 1793Combined sources
Beta strandi180 – 1823Combined sources
Helixi183 – 1886Combined sources
Beta strandi195 – 1995Combined sources
Beta strandi204 – 2063Combined sources
Beta strandi210 – 2145Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DZFX-ray1.90A1-215[»]
1I3QX-ray3.10E1-215[»]
1I50X-ray2.80E1-215[»]
1I6HX-ray3.30E1-215[»]
1K83X-ray2.80E1-215[»]
1NIKX-ray4.10E1-215[»]
1NT9X-ray4.20E1-215[»]
1PQVX-ray3.80E1-215[»]
1R5UX-ray4.50E1-215[»]
1R9SX-ray4.25E1-215[»]
1R9TX-ray3.50E1-215[»]
1SFOX-ray3.61E1-215[»]
1TWAX-ray3.20E1-215[»]
1TWCX-ray3.00E1-215[»]
1TWFX-ray2.30E1-215[»]
1TWGX-ray3.30E1-215[»]
1TWHX-ray3.40E1-215[»]
1WCMX-ray3.80E1-215[»]
1Y1VX-ray3.80E1-215[»]
1Y1WX-ray4.00E1-215[»]
1Y1YX-ray4.00E1-215[»]
1Y77X-ray4.50E1-215[»]
2B63X-ray3.80E1-215[»]
2B8KX-ray4.15E1-215[»]
2E2HX-ray3.95E1-215[»]
2E2IX-ray3.41E1-215[»]
2E2JX-ray3.50E1-215[»]
2JA5X-ray3.80E1-215[»]
2JA6X-ray4.00E1-215[»]
2JA7X-ray3.80E/Q1-215[»]
2JA8X-ray3.80E1-215[»]
2NVQX-ray2.90E1-215[»]
2NVTX-ray3.36E1-215[»]
2NVXX-ray3.60E1-215[»]
2NVYX-ray3.40E1-215[»]
2NVZX-ray4.30E1-215[»]
2R7ZX-ray3.80E1-215[»]
2R92X-ray3.80E1-215[»]
2R93X-ray4.00E1-215[»]
2VUMX-ray3.40E1-215[»]
2YU9X-ray3.40E1-215[»]
3CQZX-ray2.80E1-215[»]
3FKIX-ray3.88E1-215[»]
3GTGX-ray3.78E1-215[»]
3GTJX-ray3.42E1-215[»]
3GTKX-ray3.80E1-215[»]
3GTLX-ray3.38E1-215[»]
3GTMX-ray3.80E1-215[»]
3GTOX-ray4.00E1-215[»]
3GTPX-ray3.90E1-215[»]
3GTQX-ray3.80E1-215[»]
3H3VX-ray4.00F1-215[»]
3HOUX-ray3.20E/Q1-215[»]
3HOVX-ray3.50E1-215[»]
3HOWX-ray3.60E1-215[»]
3HOXX-ray3.65E1-215[»]
3HOYX-ray3.40E1-215[»]
3HOZX-ray3.65E1-215[»]
3I4MX-ray3.70E1-215[»]
3I4NX-ray3.90E1-215[»]
3J0Kelectron microscopy36.00E1-215[»]
3J1Nelectron microscopy16.00E1-215[»]
3K1FX-ray4.30E1-215[»]
3K7AX-ray3.80E1-215[»]
3M3YX-ray3.18E1-215[»]
3M4OX-ray3.57E1-215[»]
3PO2X-ray3.30E1-215[»]
3PO3X-ray3.30E1-215[»]
3QT1X-ray4.30E1-215[»]
3RZDX-ray3.30E1-215[»]
3RZOX-ray3.00E1-215[»]
3S14X-ray2.85E1-215[»]
3S15X-ray3.30E1-215[»]
3S16X-ray3.24E1-215[»]
3S17X-ray3.20E1-215[»]
3S1MX-ray3.13E1-215[»]
3S1NX-ray3.10E1-215[»]
3S1QX-ray3.30E1-215[»]
3S1RX-ray3.20E1-215[»]
3S2DX-ray3.20E1-215[»]
3S2HX-ray3.30E1-215[»]
4A3BX-ray3.50E1-215[»]
4A3CX-ray3.50E1-215[»]
4A3DX-ray3.40E1-215[»]
4A3EX-ray3.40E1-215[»]
4A3FX-ray3.50E1-215[»]
4A3GX-ray3.50E1-215[»]
4A3IX-ray3.80E1-215[»]
4A3JX-ray3.70E1-215[»]
4A3KX-ray3.50E1-215[»]
4A3LX-ray3.50E1-215[»]
4A3MX-ray3.90E1-215[»]
4A93X-ray3.40E1-215[»]
4BBRX-ray3.40E1-215[»]
4BBSX-ray3.60E1-215[»]
4BXXX-ray3.28E1-215[»]
4BXZX-ray4.80E1-215[»]
4BY1X-ray3.60E1-215[»]
4BY7X-ray3.15E1-215[»]
4C2MX-ray2.80E/T1-215[»]
4C3HX-ray3.27E1-215[»]
4C3IX-ray3.0E1-215[»]
4C3JX-ray3.35E1-215[»]
4V1Melectron microscopy6.60E1-215[»]
4V1Nelectron microscopy7.80E1-215[»]
4V1Oelectron microscopy9.70E1-215[»]
4X67X-ray4.10E1-215[»]
4X6AX-ray3.96E1-215[»]
4Y52X-ray3.50E1-215[»]
4Y7NX-ray3.30E1-215[»]
4YM7X-ray5.50AE/BE/CE/DE/EE/FE1-215[»]
5C3EX-ray3.70E1-215[»]
5C44X-ray3.95E1-215[»]
5C4AX-ray4.20E1-215[»]
5C4JX-ray4.00E1-215[»]
5C4XX-ray4.00E1-215[»]
5FJ8electron microscopy3.90E1-215[»]
5FJ9electron microscopy4.60E1-215[»]
5FJAelectron microscopy4.65E1-215[»]
5FMFelectron microscopy6.00E2-215[»]
5FYWelectron microscopy4.35E1-215[»]
5FZ5electron microscopy8.80E1-215[»]
5IP7X-ray3.52E2-215[»]
5IP9X-ray3.90E2-215[»]
ProteinModelPortaliP20434.
SMRiP20434. Positions 1-215.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP20434.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000013841.
HOGENOMiHOG000205213.
InParanoidiP20434.
KOiK03013.
OMAiYFITQEE.
OrthoDBiEOG092C4CGV.

Family and domain databases

Gene3Di3.40.1340.10. 1 hit.
3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR014381. DNA_RNA_pol_RPB5_euk/virus.
IPR005571. RNA_pol_Rpb5_N.
IPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
PF03871. RNA_pol_Rpb5_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000747. RPB5. 1 hit.
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF53036. SSF53036. 1 hit.
SSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P20434-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDQENERNIS RLWRAFRTVK EMVKDRGYFI TQEEVELPLE DFKAKYCDSM
60 70 80 90 100
GRPQRKMMSF QANPTEESIS KFPDMGSLWV EFCDEPSVGV KTMKTFVIHI
110 120 130 140 150
QEKNFQTGIF VYQNNITPSA MKLVPSIPPA TIETFNEAAL VVNITHHELV
160 170 180 190 200
PKHIRLSSDE KRELLKRYRL KESQLPRIQR ADPVALYLGL KRGEVVKIIR
210
KSETSGRYAS YRICM
Length:215
Mass (Da):25,079
Last modified:February 1, 1991 - v1
Checksum:i2A15F7114D69D829
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti37 – 371L → W in AAC60556 (PubMed:8488729).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53287 Genomic DNA. Translation: CAA37381.1.
X71329 Genomic DNA. Translation: CAA50472.1.
S59774 Genomic DNA. Translation: AAC60556.1.
Z36023 Genomic DNA. Translation: CAA85113.1.
BK006936 Genomic DNA. Translation: DAA07269.1.
PIRiA34588.
RefSeqiNP_009712.1. NM_001178502.1.

Genome annotation databases

EnsemblFungiiYBR154C; YBR154C; YBR154C.
GeneIDi852451.
KEGGisce:YBR154C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53287 Genomic DNA. Translation: CAA37381.1.
X71329 Genomic DNA. Translation: CAA50472.1.
S59774 Genomic DNA. Translation: AAC60556.1.
Z36023 Genomic DNA. Translation: CAA85113.1.
BK006936 Genomic DNA. Translation: DAA07269.1.
PIRiA34588.
RefSeqiNP_009712.1. NM_001178502.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1DZFX-ray1.90A1-215[»]
1I3QX-ray3.10E1-215[»]
1I50X-ray2.80E1-215[»]
1I6HX-ray3.30E1-215[»]
1K83X-ray2.80E1-215[»]
1NIKX-ray4.10E1-215[»]
1NT9X-ray4.20E1-215[»]
1PQVX-ray3.80E1-215[»]
1R5UX-ray4.50E1-215[»]
1R9SX-ray4.25E1-215[»]
1R9TX-ray3.50E1-215[»]
1SFOX-ray3.61E1-215[»]
1TWAX-ray3.20E1-215[»]
1TWCX-ray3.00E1-215[»]
1TWFX-ray2.30E1-215[»]
1TWGX-ray3.30E1-215[»]
1TWHX-ray3.40E1-215[»]
1WCMX-ray3.80E1-215[»]
1Y1VX-ray3.80E1-215[»]
1Y1WX-ray4.00E1-215[»]
1Y1YX-ray4.00E1-215[»]
1Y77X-ray4.50E1-215[»]
2B63X-ray3.80E1-215[»]
2B8KX-ray4.15E1-215[»]
2E2HX-ray3.95E1-215[»]
2E2IX-ray3.41E1-215[»]
2E2JX-ray3.50E1-215[»]
2JA5X-ray3.80E1-215[»]
2JA6X-ray4.00E1-215[»]
2JA7X-ray3.80E/Q1-215[»]
2JA8X-ray3.80E1-215[»]
2NVQX-ray2.90E1-215[»]
2NVTX-ray3.36E1-215[»]
2NVXX-ray3.60E1-215[»]
2NVYX-ray3.40E1-215[»]
2NVZX-ray4.30E1-215[»]
2R7ZX-ray3.80E1-215[»]
2R92X-ray3.80E1-215[»]
2R93X-ray4.00E1-215[»]
2VUMX-ray3.40E1-215[»]
2YU9X-ray3.40E1-215[»]
3CQZX-ray2.80E1-215[»]
3FKIX-ray3.88E1-215[»]
3GTGX-ray3.78E1-215[»]
3GTJX-ray3.42E1-215[»]
3GTKX-ray3.80E1-215[»]
3GTLX-ray3.38E1-215[»]
3GTMX-ray3.80E1-215[»]
3GTOX-ray4.00E1-215[»]
3GTPX-ray3.90E1-215[»]
3GTQX-ray3.80E1-215[»]
3H3VX-ray4.00F1-215[»]
3HOUX-ray3.20E/Q1-215[»]
3HOVX-ray3.50E1-215[»]
3HOWX-ray3.60E1-215[»]
3HOXX-ray3.65E1-215[»]
3HOYX-ray3.40E1-215[»]
3HOZX-ray3.65E1-215[»]
3I4MX-ray3.70E1-215[»]
3I4NX-ray3.90E1-215[»]
3J0Kelectron microscopy36.00E1-215[»]
3J1Nelectron microscopy16.00E1-215[»]
3K1FX-ray4.30E1-215[»]
3K7AX-ray3.80E1-215[»]
3M3YX-ray3.18E1-215[»]
3M4OX-ray3.57E1-215[»]
3PO2X-ray3.30E1-215[»]
3PO3X-ray3.30E1-215[»]
3QT1X-ray4.30E1-215[»]
3RZDX-ray3.30E1-215[»]
3RZOX-ray3.00E1-215[»]
3S14X-ray2.85E1-215[»]
3S15X-ray3.30E1-215[»]
3S16X-ray3.24E1-215[»]
3S17X-ray3.20E1-215[»]
3S1MX-ray3.13E1-215[»]
3S1NX-ray3.10E1-215[»]
3S1QX-ray3.30E1-215[»]
3S1RX-ray3.20E1-215[»]
3S2DX-ray3.20E1-215[»]
3S2HX-ray3.30E1-215[»]
4A3BX-ray3.50E1-215[»]
4A3CX-ray3.50E1-215[»]
4A3DX-ray3.40E1-215[»]
4A3EX-ray3.40E1-215[»]
4A3FX-ray3.50E1-215[»]
4A3GX-ray3.50E1-215[»]
4A3IX-ray3.80E1-215[»]
4A3JX-ray3.70E1-215[»]
4A3KX-ray3.50E1-215[»]
4A3LX-ray3.50E1-215[»]
4A3MX-ray3.90E1-215[»]
4A93X-ray3.40E1-215[»]
4BBRX-ray3.40E1-215[»]
4BBSX-ray3.60E1-215[»]
4BXXX-ray3.28E1-215[»]
4BXZX-ray4.80E1-215[»]
4BY1X-ray3.60E1-215[»]
4BY7X-ray3.15E1-215[»]
4C2MX-ray2.80E/T1-215[»]
4C3HX-ray3.27E1-215[»]
4C3IX-ray3.0E1-215[»]
4C3JX-ray3.35E1-215[»]
4V1Melectron microscopy6.60E1-215[»]
4V1Nelectron microscopy7.80E1-215[»]
4V1Oelectron microscopy9.70E1-215[»]
4X67X-ray4.10E1-215[»]
4X6AX-ray3.96E1-215[»]
4Y52X-ray3.50E1-215[»]
4Y7NX-ray3.30E1-215[»]
4YM7X-ray5.50AE/BE/CE/DE/EE/FE1-215[»]
5C3EX-ray3.70E1-215[»]
5C44X-ray3.95E1-215[»]
5C4AX-ray4.20E1-215[»]
5C4JX-ray4.00E1-215[»]
5C4XX-ray4.00E1-215[»]
5FJ8electron microscopy3.90E1-215[»]
5FJ9electron microscopy4.60E1-215[»]
5FJAelectron microscopy4.65E1-215[»]
5FMFelectron microscopy6.00E2-215[»]
5FYWelectron microscopy4.35E1-215[»]
5FZ5electron microscopy8.80E1-215[»]
5IP7X-ray3.52E2-215[»]
5IP9X-ray3.90E2-215[»]
ProteinModelPortaliP20434.
SMRiP20434. Positions 1-215.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32853. 89 interactions.
DIPiDIP-71N.
IntActiP20434. 50 interactions.
MINTiMINT-530046.

Proteomic databases

MaxQBiP20434.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYBR154C; YBR154C; YBR154C.
GeneIDi852451.
KEGGisce:YBR154C.

Organism-specific databases

EuPathDBiFungiDB:YBR154C.
SGDiS000000358. RPB5.

Phylogenomic databases

GeneTreeiENSGT00390000013841.
HOGENOMiHOG000205213.
InParanoidiP20434.
KOiK03013.
OMAiYFITQEE.
OrthoDBiEOG092C4CGV.

Enzyme and pathway databases

BioCyciYEAST:G3O-29104-MONOMER.
ReactomeiR-SCE-113418. Formation of the Early Elongation Complex.
R-SCE-674695. RNA Polymerase II Pre-transcription Events.
R-SCE-6781823. Formation of TC-NER Pre-Incision Complex.
R-SCE-6782135. Dual incision in TC-NER.
R-SCE-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-SCE-6796648. TP53 Regulates Transcription of DNA Repair Genes.
R-SCE-72086. mRNA Capping.
R-SCE-72165. mRNA Splicing - Minor Pathway.
R-SCE-73776. RNA Polymerase II Promoter Escape.
R-SCE-73779. RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
R-SCE-73780. RNA Polymerase III Chain Elongation.
R-SCE-73980. RNA Polymerase III Transcription Termination.
R-SCE-749476. RNA Polymerase III Abortive And Retractive Initiation.
R-SCE-75953. RNA Polymerase II Transcription Initiation.
R-SCE-76042. RNA Polymerase II Transcription Initiation And Promoter Clearance.
R-SCE-76061. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
R-SCE-76066. RNA Polymerase III Transcription Initiation From Type 2 Promoter.
R-SCE-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.
R-SCE-77075. RNA Pol II CTD phosphorylation and interaction with CE.

Miscellaneous databases

EvolutionaryTraceiP20434.
PROiP20434.

Family and domain databases

Gene3Di3.40.1340.10. 1 hit.
3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR014381. DNA_RNA_pol_RPB5_euk/virus.
IPR005571. RNA_pol_Rpb5_N.
IPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
PF03871. RNA_pol_Rpb5_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000747. RPB5. 1 hit.
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF53036. SSF53036. 1 hit.
SSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPAB1_YEAST
AccessioniPrimary (citable) accession number: P20434
Secondary accession number(s): D6VQE9, Q02121
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 7, 2016
This is version 171 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.