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Protein

Exodeoxyribonuclease

Gene

6

Organism
Enterobacteria phage T3 (Bacteriophage T3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

This enzyme is essential for phage DNA replication; it is believed to function in the removal of DNA-linked RNA primers. It is also necessary for host DNA degradation and phage genetic recombination.

Catalytic activityi

Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.

GO - Molecular functioni

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease (EC:3.1.11.3)
Short name:
Exonuclease
Gene namesi
Name:6
OrganismiEnterobacteria phage T3 (Bacteriophage T3)
Taxonomic identifieri10759 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065041 – 302ExodeoxyribonucleaseAdd BLAST302

Structurei

3D structure databases

ProteinModelPortaliP20321.
SMRiP20321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.1010. 1 hit.
InterProiView protein in InterPro
IPR020046. 5-3_exonucl_a-hlix_arch_N.
IPR029060. PIN_domain-like.
PfamiView protein in Pfam
PF02739. 5_3_exonuc_N. 1 hit.
SUPFAMiSSF88723. SSF88723. 1 hit.

Sequencei

Sequence statusi: Complete.

P20321-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLDLKQFY ELREGCDDKG ILVMDGDWLV FQAMSAAEFD ASWEEEIWHR
60 70 80 90 100
CCDHAKARQI LEDSIKSYET RKKAWVGAPI VLAFTDSVNW RKELVDPNYK
110 120 130 140 150
ANRKATKKPV GYFEFLEALF EREEFYCIRE PMLEGDDVMG VIASNPSAFG
160 170 180 190 200
ARKAVIISCD KDFKTIPNCD FLWCTTGNIL TQTKETADWW HLFQTIKGDM
210 220 230 240 250
TDGYSGIPGW GDTAEGFLND PFIVEPVESV LKSGKNKGQT VTKWVKRAPD
260 270 280 290 300
ATETLWDCIK SIGAKAGMTE QEIIKQGQMA RILRFEEYNY IDKEIYLWTP

RS
Length:302
Mass (Da):34,627
Last modified:February 1, 1991 - v1
Checksum:iD89C9CE2CC5D4773
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17255 Genomic DNA. Translation: CAA35147.1.
PIRiS07503.
RefSeqiNP_523327.1. NC_003298.1.

Genome annotation databases

GeneIDi927425.
KEGGivg:927425.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiEXRN_BPT3
AccessioniPrimary (citable) accession number: P20321
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: July 5, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program