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Protein

Endodeoxyribonuclease 1

Gene

3

Organism
Enterobacteria phage T3 (Bacteriophage T3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Endodeoxyribonuclease I, which is expressed in the late stage, is necessary for T3 genetic recombination and the breakdown of host DNA. In the early stage of infection, T3 DNA replicates as a linear monomer. In the late stage, the T3 DNA replicates via linear concatemers several genomes in length. The gene 3 product has also been implicated in the maturation of these concatemers.

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Endodeoxyribonuclease 1 (EC:3.1.21.2)
Alternative name(s):
Endodeoxyribonuclease I
Short name:
Endonuclease
Gene namesi
Name:3
OrganismiEnterobacteria phage T3 (Bacteriophage T3)
Taxonomic identifieri10759 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001064851 – 152Endodeoxyribonuclease 1Add BLAST152

Structurei

3D structure databases

ProteinModelPortaliP20314.
SMRiP20314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK21525.

Family and domain databases

InterProiView protein in InterPro
IPR008029. Phage_T7_Gp3_endoDNaseI.
IPR011335. Restrct_endonuc-II-like.
PfamiView protein in Pfam
PF05367. Phage_endo_I. 1 hit.
SUPFAMiSSF52980. SSF52980. 1 hit.

Sequencei

Sequence statusi: Complete.

P20314-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGAYAARCT QGRAFRSGLE DKVSKQLESK GIKFDYELWR IPYVIPESDH
60 70 80 90 100
LYTPDFLLPN GIFIETKGLW DSDDRKKHLL IREQHPELDI RLVFSSSRSK
110 120 130 140 150
LYKGSPTSYG EWCEKHGILF ADKLIPVAGV KEPKKEVPFD KFKTKKGVKK

NG
Length:152
Mass (Da):17,432
Last modified:February 1, 1991 - v1
Checksum:iBFCDE82A4C0D611B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17255 Genomic DNA. Translation: CAA35132.1.
PIRiS07505.
RefSeqiNP_523312.1. NC_003298.1.

Genome annotation databases

GeneIDi927412.
KEGGivg:927412.

Similar proteinsi

Entry informationi

Entry nameiENRN_BPT3
AccessioniPrimary (citable) accession number: P20314
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 27, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program