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Protein

Integrase

Gene

d335

Organism
Sulfolobus spindle-shape virus 1 (SSV1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei314O-(3'-phospho-DNA)-tyrosine intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Transferase
Biological processDNA integration, DNA recombination, Viral genome integration, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Integrase (EC:2.7.7.-1 Publication, EC:3.1.-.-1 Publication)
Gene namesi
ORF Names:d335
OrganismiSulfolobus spindle-shape virus 1 (SSV1)
Taxonomic identifieri244589 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageFuselloviridaeAlphafusellovirus
Virus hostiSulfolobus solfataricus [TaxID: 2287]
Proteomesi
  • UP000000854 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001975091 – 335IntegraseAdd BLAST335

Proteomic databases

PRIDEiP20214

Structurei

Secondary structure

1335
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi181 – 192Combined sources12
Helixi196 – 208Combined sources13
Helixi212 – 220Combined sources9
Helixi222 – 224Combined sources3
Beta strandi226 – 228Combined sources3
Beta strandi231 – 237Combined sources7
Beta strandi240 – 242Combined sources3
Beta strandi245 – 252Combined sources8
Helixi261 – 269Combined sources9
Helixi278 – 290Combined sources13
Helixi295 – 301Combined sources7
Beta strandi307 – 310Combined sources4
Helixi317 – 334Combined sources18

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3UXUX-ray2.71A173-335[»]
3VCFX-ray2.70A/B174-335[»]
4DKSX-ray2.70A174-335[»]
ProteinModelPortaliP20214
SMRiP20214
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family.Curated

Phylogenomic databases

OrthoDBiVOG090002KM

Family and domain databases

Gene3Di1.10.443.10, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR031857 Integrase_SSV1_C
IPR012922 ORF_D-335
PfamiView protein in Pfam
PF16795 Phage_integr_3, 1 hit
PF07935 SSV1_ORF_D-335, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit

Sequencei

Sequence statusi: Complete.

P20214-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKDKTRYKY GDYILRERKG RYYVYKLEYE NGEVKERYVG PLADVVESYL
60 70 80 90 100
KMKLGVVGDT PLQADPPGFE PGTSGSGGGK EGTERRKIAL VANLRQYATD
110 120 130 140 150
GNIKAFYDYL MNERGISEKT AKDYINAISK PYKETRDAQK AYRLFARFLA
160 170 180 190 200
SRNIIHDEFA DKILKAVKVK KANADIYIPT LEEIKRTLQL AKDYSENVYF
210 220 230 240 250
IYRIALESGV RLSEILKVLK EPERDICGND VCYYPLSWTR GYKGVFYVFH
260 270 280 290 300
ITPLKRVEVT KWAIADFERR HKDAIAIKYF RKFVASKMAE LSVPLDIIDF
310 320 330
IQGRKPTRVL TQHYVSLFGI AKEQYKKYAE WLKGV
Length:335
Mass (Da):38,860
Last modified:February 1, 1991 - v1
Checksum:i5C7217C516A5112D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07234 Genomic DNA Translation: CAA30211.1
PIRiS03212
RefSeqiNP_039778.1, NC_001338.1

Genome annotation databases

GeneIDi2559644
KEGGivg:2559644

Similar proteinsi

Entry informationi

Entry nameiVINT_SSV1
AccessioniPrimary (citable) accession number: P20214
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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