ID   RASH_RAT       STANDARD;      PRT;   189 AA.
AC   P20171;
DT   01-FEB-1991 (Rel. 17, Created)
DT   01-FEB-1991 (Rel. 17, Last sequence update)
DT   30-MAY-2000 (Rel. 39, Last annotation update)
DE   Transforming protein P21/H-RAS-1 (C-H-RAS).
GN   HRAS1 OR HRAS.
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=87064453; PubMed=3023901;
RA   Ruta M., Wolford R., Dhar R., Defeo-Jones D., Ellis R.W.,
RA   Scolnick E.M.;
RT   "Nucleotide sequence of the two rat cellular rasH genes.";
RL   Mol. Cell. Biol. 6:1706-1710(1986).
CC   -!- FUNCTION: RAS PROTEINS BIND GDP/GTP AND POSSESS INTRINSIC GTPASE
CC       ACTIVITY.
CC   -!- ENZYME REGULATION: ALTERNATE BETWEEN AN INACTIVE FORM BOUND TO GDP
CC       AND AN ACTIVE FORM BOUND TO GTP. ACTIVATED BY A GUANINE
CC       NUCLEOTIDE-EXCHANGE FACTOR (GEF) AND INACTIVATED BY A GTPASE-
CC       ACTIVATING PROTEIN (GAP).
CC   -!- SIMILARITY: BELONGS TO THE SMALL GTPASE SUPERFAMILY. RAS FAMILY.
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DR   EMBL; M13011; AAA42009.1; -.
DR   PIR; A25229; A25229.
DR   HSSP; P01112; 2GDP.
DR   InterPro; IPR003577; Ras.
DR   InterPro; IPR001806; Ras_trnsfrmng.
DR   Pfam; PF00071; ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00173; RAS; 1.
KW   Proto-oncogene; GTP-binding; Prenylation; Palmitate; Lipoprotein.
FT   NP_BIND      10     17       GTP.
FT   NP_BIND      57     61       GTP.
FT   NP_BIND     116    119       GTP.
FT   DOMAIN       32     40       EFFECTOR REGION.
FT   DOMAIN      166    185       HYPERVARIABLE REGION.
FT   LIPID       184    184       PALMITATE.
FT   LIPID       186    186       FARNESYL.
SQ   SEQUENCE   189 AA;  21314 MW;  EE6DD9B533E2856A CRC64;
     MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG
     QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI KRVKDSDDVP MVLVGNKCDL
     AARTVESRQA QDLARSYGIP YIETSAKTRQ GVEDAFYTLV REIRQHKLRK LNPPDESGLG
     CMSCKCVLS
//