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P20167 (TRPF_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:BSU22650
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length215 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 215215N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154347

Experimental info

Sequence conflict151K → Q in AAA20864. Ref.1
Sequence conflict151K → Q in AAA22868. Ref.1
Sequence conflict221E → D in AAA20864. Ref.1
Sequence conflict221E → D in AAA22868. Ref.1
Sequence conflict361K → Y in AAA20864. Ref.1
Sequence conflict361K → Y in AAA22868. Ref.1
Sequence conflict421E → Q in AAA20864. Ref.1
Sequence conflict421E → Q in AAA22868. Ref.1
Sequence conflict491N → S in AAA20864. Ref.1
Sequence conflict491N → S in AAA22868. Ref.1
Sequence conflict521R → C in AAA20864. Ref.1
Sequence conflict521R → C in AAA22868. Ref.1
Sequence conflict74 – 774KSLK → EDLN in AAA20864. Ref.1
Sequence conflict74 – 774KSLK → EDLN in AAA22868. Ref.1
Sequence conflict881K → E in AAA20864. Ref.1
Sequence conflict881K → E in AAA22868. Ref.1
Sequence conflict931A → D in AAA20864. Ref.1
Sequence conflict931A → D in AAA22868. Ref.1
Sequence conflict971K → M in AAA20864. Ref.1
Sequence conflict971K → M in AAA22868. Ref.1
Sequence conflict1001G → D in AAA20864. Ref.1
Sequence conflict1001G → D in AAA22868. Ref.1
Sequence conflict110 – 1112QD → HE in AAA20864. Ref.1
Sequence conflict110 – 1112QD → HE in AAA22868. Ref.1
Sequence conflict1231N → D in AAA20864. Ref.1
Sequence conflict1231N → D in AAA22868. Ref.1
Sequence conflict1361S → A in AAA20864. Ref.1
Sequence conflict1361S → A in AAA22868. Ref.1
Sequence conflict1471E → D in AAA20864. Ref.1
Sequence conflict1471E → D in AAA22868. Ref.1
Sequence conflict1711S → T in AAA20864. Ref.1
Sequence conflict1711S → T in AAA22868. Ref.1
Sequence conflict174 – 1785RLLKW → DLMKY in AAA20864. Ref.1
Sequence conflict174 – 1785RLLKW → DLMKY in AAA22868. Ref.1
Sequence conflict1811E → A in AAA20864. Ref.1
Sequence conflict1811E → A in AAA22868. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P20167 [UniParc].

Last modified July 28, 2009. Version 3.
Checksum: 0153C28BA53DC9ED

FASTA21524,041
        10         20         30         40         50         60 
MKKPALKYCG IRSLKDLQLA AESQADYLGF IFAESKRKVS PEDVKKWLNQ VRVEKQVAGV 

        70         80         90        100        110        120 
FVNESIETMS RIAKSLKLDV IQLHGDEKPA DAAALRKLTG CEIWKALHHQ DNTTQEIARF 

       130        140        150        160        170        180 
KDNVDGFVID SSVKGSRGGT GVAFSWECVP EYQQAAIGKR CFIAGGVNPD SITRLLKWQP 

       190        200        210 
EGIDLASGIE KNGQKDQNLM RLLEERMNRY VSISE 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence of the Bacillus subtilis tryptophan operon."
Henner D.J., Band L., Shimotsu H.
Gene 34:169-177(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[3]"Detecting and analyzing DNA sequencing errors: toward a higher quality of the Bacillus subtilis genome sequence."
Medigue C., Rose M., Viari A., Danchin A.
Genome Res. 9:1116-1127(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[4]"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION TO 92 AND 147.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M80245 Genomic DNA. Translation: AAA20864.1.
K01391 Genomic DNA. Translation: AAA22868.1.
AL009126 Genomic DNA. Translation: CAB14181.3.
PIRD22794.
RefSeqNP_390146.3. NC_000964.3.

3D structure databases

ProteinModelPortalP20167.
SMRP20167. Positions 5-210.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224308.BSU22650.

Protocols and materials databases

DNASU939006.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB14181; CAB14181; BSU22650.
GeneID939006.
KEGGbsu:BSU22650.
PATRIC18976339. VBIBacSub10457_2360.

Organism-specific databases

GenoListBSU22650. [Micado]

Phylogenomic databases

HOGENOMHOG000161598.
KOK01817.
OrthoDBEOG6N94DF.
ProtClustDBPRK01222.

Enzyme and pathway databases

BioCycBSUB:BSU22650-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_BACSU
AccessionPrimary (citable) accession number: P20167
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList